ES8404329A1 - Procedimiento de preparacion de derivados de fenetil-1-alfa-fenil-piperidin-3-propanonitrilo - Google Patents
Procedimiento de preparacion de derivados de fenetil-1-alfa-fenil-piperidin-3-propanonitriloInfo
- Publication number
- ES8404329A1 ES8404329A1 ES524907A ES524907A ES8404329A1 ES 8404329 A1 ES8404329 A1 ES 8404329A1 ES 524907 A ES524907 A ES 524907A ES 524907 A ES524907 A ES 524907A ES 8404329 A1 ES8404329 A1 ES 8404329A1
- Authority
- ES
- Spain
- Prior art keywords
- phenyl
- radical
- alpha
- preparation
- phenethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8214154A FR2531702A1 (fr) | 1982-08-16 | 1982-08-16 | Derives de phenethyl-1a-phenylperidine-3-propanenitrile, leur preparation et leur application en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
ES524907A0 ES524907A0 (es) | 1984-05-01 |
ES8404329A1 true ES8404329A1 (es) | 1984-05-01 |
Family
ID=9276888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES524907A Expired ES8404329A1 (es) | 1982-08-16 | 1983-08-12 | Procedimiento de preparacion de derivados de fenetil-1-alfa-fenil-piperidin-3-propanonitrilo |
Country Status (19)
Country | Link |
---|---|
US (1) | US4481207A (en, 2012) |
EP (1) | EP0103500B1 (en, 2012) |
JP (1) | JPS5953467A (en, 2012) |
AT (1) | ATE31924T1 (en, 2012) |
AU (1) | AU559173B2 (en, 2012) |
CA (1) | CA1239406A (en, 2012) |
DE (1) | DE3375299D1 (en, 2012) |
DK (1) | DK367983D0 (en, 2012) |
ES (1) | ES8404329A1 (en, 2012) |
FI (1) | FI832922A7 (en, 2012) |
FR (1) | FR2531702A1 (en, 2012) |
GR (1) | GR78689B (en, 2012) |
HU (1) | HU190729B (en, 2012) |
IL (1) | IL69490A (en, 2012) |
MX (1) | MX155971A (en, 2012) |
NO (1) | NO832897L (en, 2012) |
NZ (1) | NZ205250A (en, 2012) |
PT (1) | PT77194B (en, 2012) |
ZA (1) | ZA835970B (en, 2012) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8825505D0 (en) * | 1988-11-01 | 1988-12-07 | Pfizer Ltd | Therapeutic agents |
US5932594A (en) * | 1988-11-01 | 1999-08-03 | Pfizer, Inc. | Muscarinic receptor antagonists |
FR2676053B1 (fr) * | 1991-05-03 | 1993-08-27 | Sanofi Elf | Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB930459A (en) * | 1963-09-26 | 1963-07-03 | Aspro Nicholas Ltd | Diphenyl methane derivatives and methods for the preparation thereof |
GB1057145A (en) * | 1963-08-16 | 1967-02-01 | Bellon Labor Sa Roger | Phenylcyclohexylacetonitrile derivatives |
FR2302739A1 (fr) * | 1975-03-03 | 1976-10-01 | Synthelabo | Nouveaux derives du phenyl-2(piperidinyl-4)-2 acetonitrile, leurs sels, leur preparation et les medicaments qui en contiennent |
US4399286A (en) * | 1981-07-16 | 1983-08-16 | Mead Johnson & Company | Antiarrhythmic phenethylpiperidine compounds |
-
1982
- 1982-08-16 FR FR8214154A patent/FR2531702A1/fr active Granted
-
1983
- 1983-08-04 DE DE8383401613T patent/DE3375299D1/de not_active Expired
- 1983-08-04 AT AT83401613T patent/ATE31924T1/de not_active IP Right Cessation
- 1983-08-04 EP EP83401613A patent/EP0103500B1/fr not_active Expired
- 1983-08-11 HU HU832825A patent/HU190729B/hu unknown
- 1983-08-12 DK DK3679/83A patent/DK367983D0/da not_active Application Discontinuation
- 1983-08-12 CA CA000434495A patent/CA1239406A/en not_active Expired
- 1983-08-12 IL IL69490A patent/IL69490A/xx unknown
- 1983-08-12 NZ NZ205250A patent/NZ205250A/xx unknown
- 1983-08-12 ES ES524907A patent/ES8404329A1/es not_active Expired
- 1983-08-12 MX MX198372A patent/MX155971A/es unknown
- 1983-08-12 FI FI832922A patent/FI832922A7/fi not_active Application Discontinuation
- 1983-08-12 AU AU17934/83A patent/AU559173B2/en not_active Ceased
- 1983-08-12 GR GR72211A patent/GR78689B/el unknown
- 1983-08-12 JP JP58148690A patent/JPS5953467A/ja active Granted
- 1983-08-12 NO NO832897A patent/NO832897L/no unknown
- 1983-08-12 ZA ZA835970A patent/ZA835970B/xx unknown
- 1983-08-12 PT PT77194A patent/PT77194B/pt unknown
- 1983-08-15 US US06/523,349 patent/US4481207A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US4481207A (en) | 1984-11-06 |
ES524907A0 (es) | 1984-05-01 |
MX155971A (es) | 1988-06-03 |
ZA835970B (en) | 1984-04-25 |
DK367983D0 (da) | 1983-08-12 |
GR78689B (en, 2012) | 1984-09-27 |
NZ205250A (en) | 1985-07-31 |
NO832897L (no) | 1984-02-17 |
HU190729B (en) | 1986-10-28 |
FR2531702B1 (en, 2012) | 1984-12-07 |
FI832922L (fi) | 1984-02-17 |
CA1239406A (en) | 1988-07-19 |
ATE31924T1 (de) | 1988-01-15 |
JPS6125708B2 (en, 2012) | 1986-06-17 |
IL69490A (en) | 1986-11-30 |
PT77194B (fr) | 1986-03-21 |
DE3375299D1 (en) | 1988-02-18 |
EP0103500A3 (en) | 1984-11-28 |
FR2531702A1 (fr) | 1984-02-17 |
AU559173B2 (en) | 1987-02-26 |
FI832922A0 (fi) | 1983-08-12 |
FI832922A7 (fi) | 1984-02-17 |
EP0103500A2 (fr) | 1984-03-21 |
JPS5953467A (ja) | 1984-03-28 |
AU1793483A (en) | 1984-02-23 |
PT77194A (fr) | 1983-09-01 |
EP0103500B1 (fr) | 1988-01-13 |
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