ATE31924T1 - Phenethyl-1-alpha-phenyl-piperidin-3-propannitr l-derivate, ihre herstellung und therapeutische verwendung. - Google Patents
Phenethyl-1-alpha-phenyl-piperidin-3-propannitr l-derivate, ihre herstellung und therapeutische verwendung.Info
- Publication number
- ATE31924T1 ATE31924T1 AT83401613T AT83401613T ATE31924T1 AT E31924 T1 ATE31924 T1 AT E31924T1 AT 83401613 T AT83401613 T AT 83401613T AT 83401613 T AT83401613 T AT 83401613T AT E31924 T1 ATE31924 T1 AT E31924T1
- Authority
- AT
- Austria
- Prior art keywords
- radical
- propanitr
- phenethyl
- piperidine
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8214154A FR2531702A1 (fr) | 1982-08-16 | 1982-08-16 | Derives de phenethyl-1a-phenylperidine-3-propanenitrile, leur preparation et leur application en therapeutique |
| EP83401613A EP0103500B1 (de) | 1982-08-16 | 1983-08-04 | Phenethyl-1-alpha-phenyl-piperidin-3-propannitril-Derivate, ihre Herstellung und therapeutische Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE31924T1 true ATE31924T1 (de) | 1988-01-15 |
Family
ID=9276888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83401613T ATE31924T1 (de) | 1982-08-16 | 1983-08-04 | Phenethyl-1-alpha-phenyl-piperidin-3-propannitr l-derivate, ihre herstellung und therapeutische verwendung. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4481207A (de) |
| EP (1) | EP0103500B1 (de) |
| JP (1) | JPS5953467A (de) |
| AT (1) | ATE31924T1 (de) |
| AU (1) | AU559173B2 (de) |
| CA (1) | CA1239406A (de) |
| DE (1) | DE3375299D1 (de) |
| DK (1) | DK367983D0 (de) |
| ES (1) | ES8404329A1 (de) |
| FI (1) | FI832922A (de) |
| FR (1) | FR2531702A1 (de) |
| GR (1) | GR78689B (de) |
| HU (1) | HU190729B (de) |
| IL (1) | IL69490A (de) |
| MX (1) | MX155971A (de) |
| NO (1) | NO832897L (de) |
| NZ (1) | NZ205250A (de) |
| PT (1) | PT77194B (de) |
| ZA (1) | ZA835970B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5932594A (en) * | 1988-11-01 | 1999-08-03 | Pfizer, Inc. | Muscarinic receptor antagonists |
| GB8825505D0 (en) * | 1988-11-01 | 1988-12-07 | Pfizer Ltd | Therapeutic agents |
| FR2676053B1 (fr) * | 1991-05-03 | 1993-08-27 | Sanofi Elf | Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB930459A (en) * | 1963-09-26 | 1963-07-03 | Aspro Nicholas Ltd | Diphenyl methane derivatives and methods for the preparation thereof |
| GB1057145A (en) * | 1963-08-16 | 1967-02-01 | Bellon Labor Sa Roger | Phenylcyclohexylacetonitrile derivatives |
| FR2302739A1 (fr) * | 1975-03-03 | 1976-10-01 | Synthelabo | Nouveaux derives du phenyl-2(piperidinyl-4)-2 acetonitrile, leurs sels, leur preparation et les medicaments qui en contiennent |
| US4399286A (en) * | 1981-07-16 | 1983-08-16 | Mead Johnson & Company | Antiarrhythmic phenethylpiperidine compounds |
-
1982
- 1982-08-16 FR FR8214154A patent/FR2531702A1/fr active Granted
-
1983
- 1983-08-04 AT AT83401613T patent/ATE31924T1/de not_active IP Right Cessation
- 1983-08-04 EP EP83401613A patent/EP0103500B1/de not_active Expired
- 1983-08-04 DE DE8383401613T patent/DE3375299D1/de not_active Expired
- 1983-08-11 HU HU832825A patent/HU190729B/hu unknown
- 1983-08-12 FI FI832922A patent/FI832922A/fi not_active Application Discontinuation
- 1983-08-12 CA CA000434495A patent/CA1239406A/en not_active Expired
- 1983-08-12 NO NO832897A patent/NO832897L/no unknown
- 1983-08-12 GR GR72211A patent/GR78689B/el unknown
- 1983-08-12 MX MX198372A patent/MX155971A/es unknown
- 1983-08-12 AU AU17934/83A patent/AU559173B2/en not_active Ceased
- 1983-08-12 IL IL69490A patent/IL69490A/xx unknown
- 1983-08-12 DK DK3679/83A patent/DK367983D0/da not_active Application Discontinuation
- 1983-08-12 ZA ZA835970A patent/ZA835970B/xx unknown
- 1983-08-12 NZ NZ205250A patent/NZ205250A/xx unknown
- 1983-08-12 ES ES524907A patent/ES8404329A1/es not_active Expired
- 1983-08-12 JP JP58148690A patent/JPS5953467A/ja active Granted
- 1983-08-12 PT PT77194A patent/PT77194B/pt unknown
- 1983-08-15 US US06/523,349 patent/US4481207A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI832922A (fi) | 1984-02-17 |
| GR78689B (de) | 1984-09-27 |
| JPS5953467A (ja) | 1984-03-28 |
| AU559173B2 (en) | 1987-02-26 |
| MX155971A (es) | 1988-06-03 |
| PT77194B (fr) | 1986-03-21 |
| ZA835970B (en) | 1984-04-25 |
| ES524907A0 (es) | 1984-05-01 |
| US4481207A (en) | 1984-11-06 |
| DE3375299D1 (en) | 1988-02-18 |
| FI832922A0 (fi) | 1983-08-12 |
| NZ205250A (en) | 1985-07-31 |
| HU190729B (en) | 1986-10-28 |
| CA1239406A (en) | 1988-07-19 |
| EP0103500A2 (de) | 1984-03-21 |
| PT77194A (fr) | 1983-09-01 |
| FR2531702A1 (fr) | 1984-02-17 |
| NO832897L (no) | 1984-02-17 |
| EP0103500A3 (en) | 1984-11-28 |
| AU1793483A (en) | 1984-02-23 |
| FR2531702B1 (de) | 1984-12-07 |
| DK367983D0 (da) | 1983-08-12 |
| JPS6125708B2 (de) | 1986-06-17 |
| EP0103500B1 (de) | 1988-01-13 |
| IL69490A (en) | 1986-11-30 |
| ES8404329A1 (es) | 1984-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |