ES8403494A1 - "un procedimiento para la preparacion de derivados de s-adenosilmetionina". - Google Patents

"un procedimiento para la preparacion de derivados de s-adenosilmetionina".

Info

Publication number
ES8403494A1
ES8403494A1 ES515613A ES515613A ES8403494A1 ES 8403494 A1 ES8403494 A1 ES 8403494A1 ES 515613 A ES515613 A ES 515613A ES 515613 A ES515613 A ES 515613A ES 8403494 A1 ES8403494 A1 ES 8403494A1
Authority
ES
Spain
Prior art keywords
contain
preparation
active principle
therapeutic compositions
adenosylmethionine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515613A
Other languages
English (en)
Other versions
ES515613A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch SRL filed Critical Bioresearch SRL
Publication of ES515613A0 publication Critical patent/ES515613A0/es
Publication of ES8403494A1 publication Critical patent/ES8403494A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE PARTE DE UNA SAL DE S-ADENOSILMETIONINA Y SE LA HACE REACCIONAR CON EL ALCOHOL REQUERIDO A REFLUJO, EN PRESENCIA DE UN 1 A UN 3 DE ACIDO SULFURICO, A BAJA TEMPERATURA; SEGUNDA, EL PRODUCTO OBTENIDO SE PURIFICA PASANDOLO A TRAVES DE UNA RESINA INTERCAMBIADORA DE ACIDO DEBIL Y ELUYENDOLO CON UNA SOLUCION DILUIDA DEL ACIDO DE ANION A CORRESPONDIENTE; Y POR ULTIMO, SE ADICIONA A LA SOLUCION OBTENIDA, DESPUES DE SER CONCENTRADA, LA CANTIDAD ESTEQUIOMETRICA DE ACIDO NECESARIA PARA OBTENER EL VALOR ELEGIDODE N.DE APLICACION DE PREPARADOS FARMACEUTICOS UTILIZABLES EN LA TERAPIA HUMANA.
ES515613A 1981-09-11 1982-09-10 "un procedimiento para la preparacion de derivados de s-adenosilmetionina". Expired ES8403494A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23940/81A IT1139974B (it) 1981-09-11 1981-09-11 Derivati della s-adenosilmetionina,processo per la preparazione e composizioni terapeutiche che li contengono come principio attivo

Publications (2)

Publication Number Publication Date
ES515613A0 ES515613A0 (es) 1984-04-01
ES8403494A1 true ES8403494A1 (es) 1984-04-01

Family

ID=11211012

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515613A Expired ES8403494A1 (es) 1981-09-11 1982-09-10 "un procedimiento para la preparacion de derivados de s-adenosilmetionina".

Country Status (25)

Country Link
US (1) US4558122A (es)
EP (1) EP0074555B1 (es)
JP (1) JPS5857397A (es)
AT (1) ATE14884T1 (es)
AU (1) AU564577B2 (es)
CA (1) CA1213886A (es)
CS (1) CS241123B2 (es)
DE (1) DE3265425D1 (es)
DK (2) DK149957C (es)
ES (1) ES8403494A1 (es)
FI (1) FI74290C (es)
GR (1) GR76720B (es)
HU (1) HU186117B (es)
IL (1) IL66713A (es)
IT (1) IT1139974B (es)
MX (1) MX5670A (es)
NO (1) NO153397C (es)
NZ (1) NZ201824A (es)
PL (1) PL141706B1 (es)
PT (1) PT75516B (es)
RO (1) RO85286B (es)
RU (1) RU2041235C1 (es)
SU (1) SU1340592A3 (es)
YU (1) YU43092B (es)
ZA (1) ZA826408B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1169773B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Processo per la produzione di sali stabili della solfo-adenosil-l-metionina
CA1291092C (en) * 1988-03-11 1991-10-22 Donald A. Poole Easy opening gable top carton
IT1229514B (it) * 1989-01-30 1991-09-03 Farmhispania S A A Montme Glicoconiugati anfifilici sintetici per impiego neurologico.
JPH02290896A (ja) * 1989-04-28 1990-11-30 Fuji Kagaku Kogyo Kk 新規なｓ―アデノシルメチオニン誘導体
US5180714A (en) * 1990-10-31 1993-01-19 Health Research, Inc. Adenosine compounds for the treatment of diseases caused by parasitic protozoa
US8642581B1 (en) 2000-02-11 2014-02-04 Brian D. Halevie-Goldman Compositions and methods for the production of S-adenosylmethionine within the body
US6649753B2 (en) * 2001-06-07 2003-11-18 Orchid Chemicals & Pharmaceuticals Ltd. Stable salts of S-adenosyl-L-methionine (SAMe) and the process for their preparation
US20040116351A1 (en) * 2002-12-06 2004-06-17 Fast Balance, Inc. Method for enhancing the natural reward system for exercise
US20050272687A1 (en) * 2004-06-08 2005-12-08 Hebert Rolland F Stable S-adenosyl-l-methionine
US20090012036A1 (en) * 2005-05-24 2009-01-08 Hebert Rolland F Stable S-adenosyl-L-methionine
ITMI20060629A1 (it) * 2006-03-31 2007-10-01 Daniele Giovannone Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
JP2008013509A (ja) * 2006-07-07 2008-01-24 Fujifilm Corp Ｓ−アデノシルメチオニンの保存方法
ITMI20071374A1 (it) * 2007-07-10 2009-01-11 Gnosis Spa Sali stabili di s-adenosilmetionina e processo per il loro ottenimento.
US20100004191A1 (en) * 2008-07-01 2010-01-07 Rolland F Hebert Compositions of S-adenosyl-L-methionine.
US20130210664A1 (en) 2010-08-05 2013-08-15 Cellzome Ag Methods for the Identification of Methyltransferase Interacting Molecules and for the Purification of Methyltransferase Proteins
ES2824807T3 (es) 2013-01-16 2021-05-13 Hebert Sam E Llc Sales de indol-3-propionato estables de S-adenosil-L-metionina
WO2015028927A1 (en) * 2013-08-25 2015-03-05 Mahesh Kandula Compositions and methods for the treatment of metabolic diseases
TR201807235T4 (tr) 2015-10-05 2018-06-21 Tetra Laval Holdings & Finance Bir kapağın bir konteyner üzerine uygulanmasına yönelik bir uygulama ünitesi.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2969353A (en) * 1957-02-06 1961-01-24 Merck & Co Inc Process for the preparation of "active methionine" and products obtained thereby
DE1803978C2 (de) * 1968-10-18 1985-05-02 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Gewinnung von S-Adenosyl-l-methionin und S-Adenosyl-l-ethionin
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
US4028183A (en) * 1973-06-27 1977-06-07 Bioresearch Limited Process of preparing double salts of S-adenosyl-L-methionine
IE39517B1 (en) * 1973-06-27 1978-10-25 Bioresearch Sas Double salts of s-adenosyl-l-methhionine
JPS5320998B2 (es) * 1974-06-13 1978-06-29
FR2275220A1 (fr) * 1974-06-21 1976-01-16 Merieux Inst Procede d'obtention de sels organiques de la s.adenosyl-l-methionine. nouveaux sels organiques obtenus des medicaments comprenant un ou plusieurs nouveaux sels obtenus
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
GB2001976B (en) * 1977-08-03 1982-03-10 Yamasa Shoyu Kk S-adenosyl-l-methionine compositions and production thereof
GB2064523B (en) * 1979-12-04 1983-06-29 Kanegafuchi Chemical Ind Stable composition of s-adenosyl-l-methionine
JPS5699499A (en) * 1980-01-10 1981-08-10 Kanegafuchi Chem Ind Co Ltd Composition containing s-adenosyl-l-methionine, and its preparation
JPS56145299A (en) * 1980-04-11 1981-11-11 Kanegafuchi Chem Ind Co Ltd Purification of s-adenosyl-l-methionine
JPS57156500A (en) * 1981-03-23 1982-09-27 Kanegafuchi Chem Ind Co Ltd Composition containing s-adenosyl-l-methionine and its preparation

Also Published As

Publication number Publication date
DK149957B (da) 1986-11-03
ES515613A0 (es) 1984-04-01
CS656082A2 (en) 1985-07-16
ZA826408B (en) 1983-07-27
DK349085D0 (da) 1985-08-01
MX5670A (es) 1994-01-31
SU1340592A3 (ru) 1987-09-23
IT1139974B (it) 1986-09-24
FI74290B (fi) 1987-09-30
RU2041235C1 (ru) 1995-08-09
DK155332B (da) 1989-03-28
US4558122A (en) 1985-12-10
NO153397B (no) 1985-12-02
PT75516A (en) 1982-10-01
YU204682A (en) 1985-06-30
YU43092B (en) 1989-02-28
PL238201A1 (en) 1983-05-09
IT8123940A0 (it) 1981-09-11
IL66713A (en) 1987-08-31
RO85286A (ro) 1984-09-29
JPH0149276B2 (es) 1989-10-24
HU186117B (en) 1985-06-28
AU564577B2 (en) 1987-08-20
DK155332C (da) 1989-08-14
FI823142A0 (fi) 1982-09-10
JPS5857397A (ja) 1983-04-05
PL141706B1 (en) 1987-08-31
FI823142L (fi) 1983-03-12
AU8813582A (en) 1983-03-17
NO153397C (no) 1986-03-12
FI74290C (fi) 1988-01-11
EP0074555B1 (en) 1985-08-14
DK149957C (da) 1987-06-15
RO85286B (ro) 1984-10-30
DK349085A (da) 1985-08-01
DE3265425D1 (en) 1985-09-19
CS241123B2 (en) 1986-03-13
ATE14884T1 (de) 1985-08-15
DK405382A (da) 1983-03-12
EP0074555A1 (en) 1983-03-23
GR76720B (es) 1984-08-29
CA1213886A (en) 1986-11-12
NO823088L (no) 1983-03-14
PT75516B (en) 1985-07-26
NZ201824A (en) 1986-05-09
IL66713A0 (en) 1982-12-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201