ES8307777A1 - Procedimiento de preparacion de nuevas 2-(4-fenilpiperaziniletil) anilinas, asi como de sus sales de adicion no toxicas. - Google Patents

Procedimiento de preparacion de nuevas 2-(4-fenilpiperaziniletil) anilinas, asi como de sus sales de adicion no toxicas.

Info

Publication number
ES8307777A1
ES8307777A1 ES517096A ES517096A ES8307777A1 ES 8307777 A1 ES8307777 A1 ES 8307777A1 ES 517096 A ES517096 A ES 517096A ES 517096 A ES517096 A ES 517096A ES 8307777 A1 ES8307777 A1 ES 8307777A1
Authority
ES
Spain
Prior art keywords
anilines
group
piperazinylethyl
medicine
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES517096A
Other languages
English (en)
Other versions
ES517096A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortial SA
Original Assignee
Cortial SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortial SA filed Critical Cortial SA
Publication of ES8307777A1 publication Critical patent/ES8307777A1/es
Publication of ES517096A0 publication Critical patent/ES517096A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 2-(4-FENILPIPERAZINILETIL) ANILINAS, DE FORMULA GENERAL (I), EN LA QUE R<1 SIGNIFICA H O SUSTITUYENTES SITUADOS EN ORTO, META O PARA, TALES COMO CH<3, CF<3, F, CL O OCH<3; Y R<2 Y R<3 IGUALES O DIFERENTES, REPRESENTAN H O ALCOXI INFERIOR DE CL, PUDIENDO R<2 Y R<3 CONSTITUIR CONJUNTAMENTE UNA CADENA -O-CH<2-O-CH<2, Y SUS SALES FARMACOLOGICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN 2-(2-HALOGENO-ETIL) 1-NITROBENCENO Y UNA N-FENILPIPERAZINA, Y A CONTINUACION SE REDUCE EL DERIVADO NITROGENADO ASI OBTENIDO. DE APLICACION EN TRATAMIENTOS TERAPEUTICOS.
ES517096A 1981-11-03 1982-11-03 Procedimiento de preparacion de nuevas 2-(4-fenilpiperaziniletil) anilinas, asi como de sus sales de adicion no toxicas. Granted ES517096A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8120564A FR2515648A1 (fr) 1981-11-03 1981-11-03 Nouvelles (phenyl-4 piperazinylethyl)-2 anilines, leur methode de preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
ES8307777A1 true ES8307777A1 (es) 1983-08-01
ES517096A0 ES517096A0 (es) 1983-08-01

Family

ID=9263640

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517096A Granted ES517096A0 (es) 1981-11-03 1982-11-03 Procedimiento de preparacion de nuevas 2-(4-fenilpiperaziniletil) anilinas, asi como de sus sales de adicion no toxicas.

Country Status (11)

Country Link
US (1) US4668681A (es)
EP (1) EP0078756B1 (es)
JP (1) JPS58126878A (es)
CA (1) CA1210006A (es)
DE (1) DE3269872D1 (es)
ES (1) ES517096A0 (es)
FR (1) FR2515648A1 (es)
MA (1) MA19634A1 (es)
OA (1) OA07244A (es)
PT (1) PT75775B (es)
ZA (1) ZA828044B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8619472D0 (en) * 1986-08-09 1986-09-17 Pfizer Ltd Anti-arrhythmia agents
US5219855A (en) * 1988-01-29 1993-06-15 Mitsubishi Kasei Corporation Anxiolytic drug
FR2632641B1 (fr) * 1988-06-13 1990-10-12 Irceba ((aryl-4-piperazinyl-1)-2 ethoxy)-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR78756E (fr) * 1957-11-22 1962-09-07 Système de sécurité incorporé pour charrue
NL251385A (es) * 1959-12-21
GB971041A (en) * 1960-02-02 1964-09-30 May & Baker Ltd New phenylpiperazine compounds
GB953005A (en) * 1961-02-24 1964-03-18 Soc Ind Fab Antibiotiques Sifa Substituted n-phenylethyl-n-phenyl-piperazines
BE620235R (fr) * 1961-07-14 1963-01-14 May & Baker Ltd Nouvelles pipérazines N-N disubstituéer
US3562277A (en) * 1967-09-06 1971-02-09 Shulton Inc Ketonic derivatives of phenyl piperazines
DE2325633A1 (de) * 1973-05-21 1974-12-12 Boehringer Sohn Ingelheim Piperazinderivate
US3981864A (en) * 1973-09-08 1976-09-21 Eisai Co., Ltd. 1,3-Benzodioxol derivatives
US4094980A (en) * 1974-09-03 1978-06-13 Boehringer Ingelheim Gmbh N-[1-(3',4'-methylenedioxy-phenyl)-propyl-(2)]-N'-phenyl-piperazines and salts thereof
FR2476644A1 (fr) * 1980-02-21 1981-08-28 Sarget Lab Orthoarylydeneaminophenethylamine, leur preparation et leur utilisation therapeutique

Also Published As

Publication number Publication date
EP0078756A1 (fr) 1983-05-11
MA19634A1 (fr) 1983-07-01
EP0078756B1 (fr) 1986-03-12
ZA828044B (en) 1983-08-31
PT75775A (en) 1982-12-01
DE3269872D1 (en) 1986-04-17
FR2515648A1 (fr) 1983-05-06
FR2515648B1 (es) 1984-08-24
PT75775B (en) 1985-07-26
JPS58126878A (ja) 1983-07-28
OA07244A (fr) 1984-04-30
CA1210006A (fr) 1986-08-19
ES517096A0 (es) 1983-08-01
US4668681A (en) 1987-05-26

Similar Documents

Publication Publication Date Title
PH17873A (en) Novel azole compounds,their preparation,their use for crop treatment,and agents for this purpose
ZA911403B (en) Derivatives having a naphthalene structure,process for preparing these and pharmaceutical compositions containing them
MY102087A (en) Phenethanolamine derivatives.
MY132565A (en) Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha (ppar)
ES8706630A1 (es) Procedimiento para la preparacion de derivados n-acilados del-triptofano
RU92016545A (ru) Гетероциклические соединения, способ их получения и фармацевтическая композиция
EP0132764A3 (en) New compounds derived from diphenyl-methylene-ethylamine
ATE2622T1 (de) 2-niedrigalkyl-7-substituierte-2 oder 3-cephem-4- carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
SE8102220L (sv) Anvendning av substituerade derivat av 4-fenyl-4-oxo-2-butensyra sasom lekemedel
ATE173252T1 (de) Arylmorpholine, herstellung und verwendung
ES8307777A1 (es) Procedimiento de preparacion de nuevas 2-(4-fenilpiperaziniletil) anilinas, asi como de sus sales de adicion no toxicas.
ATE99934T1 (de) Heteroaryl-3-oxo-propannitril-derivate, nuetzlich zur behandlung von rheumatoider arthritis und anderen autoimmunkrankheiten.
ZA872693B (en) Thiodiazolylurea-containing agent for defoliating plants
KR927003537A (ko) 4, 5-사이클로알카노-3-벤즈아제핀-7-올 유도체 및 이의 용도
JPS5615283A (en) Tetrahydropyridylindole novel derivatives* their salt* these manufacture* use as drug and composition containing same
DE3750464T2 (de) Pharmazeutisches Präparat zur Behandlung des Katarakts.
SE8904127D0 (sv) New biocyclic amino-substituted compounds
DE3460841D1 (en) Mercaptoacetic acid and 3-mercaptopropionic acid amide derivatives for use in treatment of a human or animal body, some new derivatives and pharmaceutical compositions containing them
ATE19244T1 (de) 2-piperazinyl-4-phenyl-quinazolin-derivate mit antidepressiven eigenschaften, verfahren zu deren herstellung und diese enthaltende arzneimitteln.
KR930703013A (ko) 항당뇨병제로서 유용한 신규한 글루코하이드롤라제 억제제
ES8307778A1 (es) Procedimiento para preparar difenilbutil-1-piperazinocarboxilatos.
ES8201539A1 (es) Procedimiento de preparacion de nuevas ortoarilideneaminofe-netilaminas y de sus sales de adicion con acidos farmacolo- gicamente compatibles
SE8006142L (sv) 1,2,4-triazol-3-tioler
KR940002268A (ko) 21-클로로-프레그난 유도체
HUT53638A (en) Process for producing 15-amino-substituted 20,21-dinoreburnamenie derivatives and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506