ES8305770A1 - Un procedimiento para la preparacion de bis-esteres de metanodiol. - Google Patents
Un procedimiento para la preparacion de bis-esteres de metanodiol.Info
- Publication number
- ES8305770A1 ES8305770A1 ES510657A ES510657A ES8305770A1 ES 8305770 A1 ES8305770 A1 ES 8305770A1 ES 510657 A ES510657 A ES 510657A ES 510657 A ES510657 A ES 510657A ES 8305770 A1 ES8305770 A1 ES 8305770A1
- Authority
- ES
- Spain
- Prior art keywords
- bis
- esters
- reaction
- formula
- methanediol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- CKFGINPQOCXMAZ-UHFFFAOYSA-N methanediol Chemical compound OCO CKFGINPQOCXMAZ-UHFFFAOYSA-N 0.000 title 2
- QWOJMRHUQHTCJG-UHFFFAOYSA-N CC([CH2-])=O Chemical class CC([CH2-])=O QWOJMRHUQHTCJG-UHFFFAOYSA-N 0.000 title 1
- 229960003022 amoxicillin Drugs 0.000 title 1
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 title 1
- 229960000723 ampicillin Drugs 0.000 title 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 title 1
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 title 1
- FKENQMMABCRJMK-RITPCOANSA-N sulbactam Chemical compound O=S1(=O)C(C)(C)[C@H](C(O)=O)N2C(=O)C[C@H]21 FKENQMMABCRJMK-RITPCOANSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical group [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
- C07D499/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/80—Compounds with a nitrogen-containing hetero ring, attached with the ring nitrogen atom in position 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24650381A | 1981-03-23 | 1981-03-23 | |
| US06/246,504 US4321196A (en) | 1981-03-23 | 1981-03-23 | Bis-esters of methanediol with acetonides of ampicillin or amoxicillin and penicillanic acid 1,1-dioxide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES510657A0 ES510657A0 (es) | 1983-04-16 |
| ES8305770A1 true ES8305770A1 (es) | 1983-04-16 |
Family
ID=26938034
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES510657A Expired ES8305770A1 (es) | 1981-03-23 | 1982-03-22 | Un procedimiento para la preparacion de bis-esteres de metanodiol. |
| ES518997A Granted ES518997A0 (es) | 1981-03-23 | 1983-01-14 | Un procedimiento para la preparacion de bis-esteres de metanodiol. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES518997A Granted ES518997A0 (es) | 1981-03-23 | 1983-01-14 | Un procedimiento para la preparacion de bis-esteres de metanodiol. |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0061281B1 (en, 2012) |
| KR (1) | KR850001630B1 (en, 2012) |
| AR (1) | AR231297A1 (en, 2012) |
| AU (1) | AU527916B2 (en, 2012) |
| BG (2) | BG39297A3 (en, 2012) |
| CA (1) | CA1178575A (en, 2012) |
| CS (1) | CS228537B2 (en, 2012) |
| DD (1) | DD202578A5 (en, 2012) |
| DE (1) | DE3261166D1 (en, 2012) |
| DK (1) | DK159159C (en, 2012) |
| EG (1) | EG15802A (en, 2012) |
| ES (2) | ES8305770A1 (en, 2012) |
| FI (1) | FI74018C (en, 2012) |
| GB (1) | GB2095249A (en, 2012) |
| GR (1) | GR76479B (en, 2012) |
| IE (1) | IE52653B1 (en, 2012) |
| IL (1) | IL65305A (en, 2012) |
| IN (1) | IN157669B (en, 2012) |
| NO (1) | NO159660C (en, 2012) |
| PL (2) | PL131262B1 (en, 2012) |
| PT (1) | PT74623B (en, 2012) |
| RO (2) | RO83699B (en, 2012) |
| SU (1) | SU1122229A3 (en, 2012) |
| YU (1) | YU42760B (en, 2012) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR910009271B1 (ko) * | 1989-06-20 | 1991-11-08 | 김영설 | 1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염 |
| US7838708B2 (en) | 2001-06-20 | 2010-11-23 | Grt, Inc. | Hydrocarbon conversion process improvements |
| MXPA06000470A (es) | 2003-07-15 | 2006-08-23 | Grt Inc | Sintesis de hidrocarburos. |
| US20050171393A1 (en) | 2003-07-15 | 2005-08-04 | Lorkovic Ivan M. | Hydrocarbon synthesis |
| US7674941B2 (en) | 2004-04-16 | 2010-03-09 | Marathon Gtf Technology, Ltd. | Processes for converting gaseous alkanes to liquid hydrocarbons |
| US8642822B2 (en) | 2004-04-16 | 2014-02-04 | Marathon Gtf Technology, Ltd. | Processes for converting gaseous alkanes to liquid hydrocarbons using microchannel reactor |
| US20060100469A1 (en) | 2004-04-16 | 2006-05-11 | Waycuilis John J | Process for converting gaseous alkanes to olefins and liquid hydrocarbons |
| US8173851B2 (en) | 2004-04-16 | 2012-05-08 | Marathon Gtf Technology, Ltd. | Processes for converting gaseous alkanes to liquid hydrocarbons |
| US20080275284A1 (en) | 2004-04-16 | 2008-11-06 | Marathon Oil Company | Process for converting gaseous alkanes to liquid hydrocarbons |
| US7244867B2 (en) | 2004-04-16 | 2007-07-17 | Marathon Oil Company | Process for converting gaseous alkanes to liquid hydrocarbons |
| EA013629B1 (ru) | 2006-02-03 | 2010-06-30 | ДжиАрТи, ИНК. | Способ отделения легких газов от галогенов |
| US7579510B2 (en) | 2006-02-03 | 2009-08-25 | Grt, Inc. | Continuous process for converting natural gas to liquid hydrocarbons |
| US7998438B2 (en) | 2007-05-24 | 2011-08-16 | Grt, Inc. | Zone reactor incorporating reversible hydrogen halide capture and release |
| US8282810B2 (en) | 2008-06-13 | 2012-10-09 | Marathon Gtf Technology, Ltd. | Bromine-based method and system for converting gaseous alkanes to liquid hydrocarbons using electrolysis for bromine recovery |
| SG192538A1 (en) | 2008-07-18 | 2013-08-30 | Grt Inc | Continuous process for converting natural gas to liquid hydrocarbons |
| US8198495B2 (en) | 2010-03-02 | 2012-06-12 | Marathon Gtf Technology, Ltd. | Processes and systems for the staged synthesis of alkyl bromides |
| US8367884B2 (en) | 2010-03-02 | 2013-02-05 | Marathon Gtf Technology, Ltd. | Processes and systems for the staged synthesis of alkyl bromides |
| US8815050B2 (en) | 2011-03-22 | 2014-08-26 | Marathon Gtf Technology, Ltd. | Processes and systems for drying liquid bromine |
| US8436220B2 (en) | 2011-06-10 | 2013-05-07 | Marathon Gtf Technology, Ltd. | Processes and systems for demethanization of brominated hydrocarbons |
| US8829256B2 (en) | 2011-06-30 | 2014-09-09 | Gtc Technology Us, Llc | Processes and systems for fractionation of brominated hydrocarbons in the conversion of natural gas to liquid hydrocarbons |
| US8802908B2 (en) | 2011-10-21 | 2014-08-12 | Marathon Gtf Technology, Ltd. | Processes and systems for separate, parallel methane and higher alkanes' bromination |
| US9193641B2 (en) | 2011-12-16 | 2015-11-24 | Gtc Technology Us, Llc | Processes and systems for conversion of alkyl bromides to higher molecular weight hydrocarbons in circulating catalyst reactor-regenerator systems |
| CN111440194A (zh) * | 2020-04-22 | 2020-07-24 | 华南农业大学 | 一种阿莫西林衍生物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE49880B1 (en) * | 1979-02-13 | 1986-01-08 | Leo Pharm Prod Ltd | Penicillin derivatives |
| US4244951A (en) * | 1979-05-16 | 1981-01-13 | Pfizer Inc. | Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide |
-
1982
- 1982-01-04 IN IN07/DEL/82A patent/IN157669B/en unknown
- 1982-02-19 BG BG058114A patent/BG39297A3/xx unknown
- 1982-02-19 BG BG055479A patent/BG39113A3/xx unknown
- 1982-02-23 CS CS821227A patent/CS228537B2/cs unknown
- 1982-02-24 RO RO106729A patent/RO83699B/ro unknown
- 1982-02-24 RO RO112623A patent/RO86859B/ro unknown
- 1982-02-24 SU SU823394406A patent/SU1122229A3/ru active
- 1982-03-01 PL PL1982239265A patent/PL131262B1/pl unknown
- 1982-03-01 PL PL1982235275A patent/PL130553B1/pl unknown
- 1982-03-16 EP EP82301317A patent/EP0061281B1/en not_active Expired
- 1982-03-16 GB GB8207652A patent/GB2095249A/en not_active Withdrawn
- 1982-03-16 DE DE8282301317T patent/DE3261166D1/de not_active Expired
- 1982-03-18 NO NO820896A patent/NO159660C/no unknown
- 1982-03-18 GR GR67642A patent/GR76479B/el unknown
- 1982-03-19 AR AR288811A patent/AR231297A1/es active
- 1982-03-19 DD DD82238307A patent/DD202578A5/de not_active IP Right Cessation
- 1982-03-21 EG EG145/82A patent/EG15802A/xx active
- 1982-03-22 AU AU81762/82A patent/AU527916B2/en not_active Ceased
- 1982-03-22 FI FI820995A patent/FI74018C/fi not_active IP Right Cessation
- 1982-03-22 ES ES510657A patent/ES8305770A1/es not_active Expired
- 1982-03-22 CA CA000399008A patent/CA1178575A/en not_active Expired
- 1982-03-22 PT PT74623A patent/PT74623B/pt not_active IP Right Cessation
- 1982-03-22 IE IE655/82A patent/IE52653B1/en not_active IP Right Cessation
- 1982-03-22 IL IL65305A patent/IL65305A/xx unknown
- 1982-03-22 KR KR8201219A patent/KR850001630B1/ko not_active Expired
- 1982-03-22 DK DK126882A patent/DK159159C/da not_active IP Right Cessation
- 1982-03-22 YU YU617/82A patent/YU42760B/xx unknown
-
1983
- 1983-01-14 ES ES518997A patent/ES518997A0/es active Granted
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |