DK159159C - Analogifremgangsmaade til fremstilling af bis-estere af methandiol med et acetonid af ampicillin eller amoxicillin og penicillan-syre-1,1-dioxid eller farmaceutiske acceptable syreadditionssalte af disse bis-estere - Google Patents

Analogifremgangsmaade til fremstilling af bis-estere af methandiol med et acetonid af ampicillin eller amoxicillin og penicillan-syre-1,1-dioxid eller farmaceutiske acceptable syreadditionssalte af disse bis-estere

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Publication number
DK159159C
DK159159C DK126882A DK126882A DK159159C DK 159159 C DK159159 C DK 159159C DK 126882 A DK126882 A DK 126882A DK 126882 A DK126882 A DK 126882A DK 159159 C DK159159 C DK 159159C
Authority
DK
Denmark
Prior art keywords
bis
methandiol
amoxicillin
acetonide
ampicillin
Prior art date
Application number
DK126882A
Other languages
English (en)
Other versions
DK159159B (da
DK126882A (da
Inventor
Thomas Charles Crawford
Constantine Sklavounos
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/246,504 external-priority patent/US4321196A/en
Application filed by Pfizer filed Critical Pfizer
Publication of DK126882A publication Critical patent/DK126882A/da
Publication of DK159159B publication Critical patent/DK159159B/da
Application granted granted Critical
Publication of DK159159C publication Critical patent/DK159159C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/28Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
    • C07D499/32Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/80Compounds with a nitrogen-containing hetero ring, attached with the ring nitrogen atom in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
DK126882A 1981-03-23 1982-03-22 Analogifremgangsmaade til fremstilling af bis-estere af methandiol med et acetonid af ampicillin eller amoxicillin og penicillan-syre-1,1-dioxid eller farmaceutiske acceptable syreadditionssalte af disse bis-estere DK159159C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24650381A 1981-03-23 1981-03-23
US06/246,504 US4321196A (en) 1981-03-23 1981-03-23 Bis-esters of methanediol with acetonides of ampicillin or amoxicillin and penicillanic acid 1,1-dioxide
US24650481 1981-03-23
US24650381 1981-03-23

Publications (3)

Publication Number Publication Date
DK126882A DK126882A (da) 1982-09-24
DK159159B DK159159B (da) 1990-09-10
DK159159C true DK159159C (da) 1991-02-11

Family

ID=26938034

Family Applications (1)

Application Number Title Priority Date Filing Date
DK126882A DK159159C (da) 1981-03-23 1982-03-22 Analogifremgangsmaade til fremstilling af bis-estere af methandiol med et acetonid af ampicillin eller amoxicillin og penicillan-syre-1,1-dioxid eller farmaceutiske acceptable syreadditionssalte af disse bis-estere

Country Status (24)

Country Link
EP (1) EP0061281B1 (da)
KR (1) KR850001630B1 (da)
AR (1) AR231297A1 (da)
AU (1) AU527916B2 (da)
BG (2) BG39113A3 (da)
CA (1) CA1178575A (da)
CS (1) CS228537B2 (da)
DD (1) DD202578A5 (da)
DE (1) DE3261166D1 (da)
DK (1) DK159159C (da)
EG (1) EG15802A (da)
ES (2) ES8305770A1 (da)
FI (1) FI74018C (da)
GB (1) GB2095249A (da)
GR (1) GR76479B (da)
IE (1) IE52653B1 (da)
IL (1) IL65305A (da)
IN (1) IN157669B (da)
NO (1) NO159660C (da)
PL (2) PL130553B1 (da)
PT (1) PT74623B (da)
RO (2) RO86859B (da)
SU (1) SU1122229A3 (da)
YU (1) YU42760B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910009271B1 (ko) * 1989-06-20 1991-11-08 김영설 1,1-디옥소페닐실라노일 옥시메틸 D-6-[α-(메틸렌아미노)페닐-아세트아미도]-페니실라네이트와 그의 파라-톨루엔술폰산염
US7838708B2 (en) 2001-06-20 2010-11-23 Grt, Inc. Hydrocarbon conversion process improvements
US20050171393A1 (en) 2003-07-15 2005-08-04 Lorkovic Ivan M. Hydrocarbon synthesis
RU2366642C2 (ru) 2003-07-15 2009-09-10 Джи Ар Ти, Инк. Синтез углеводородов
US7674941B2 (en) 2004-04-16 2010-03-09 Marathon Gtf Technology, Ltd. Processes for converting gaseous alkanes to liquid hydrocarbons
US20080275284A1 (en) 2004-04-16 2008-11-06 Marathon Oil Company Process for converting gaseous alkanes to liquid hydrocarbons
US8642822B2 (en) 2004-04-16 2014-02-04 Marathon Gtf Technology, Ltd. Processes for converting gaseous alkanes to liquid hydrocarbons using microchannel reactor
US8173851B2 (en) 2004-04-16 2012-05-08 Marathon Gtf Technology, Ltd. Processes for converting gaseous alkanes to liquid hydrocarbons
US20060100469A1 (en) 2004-04-16 2006-05-11 Waycuilis John J Process for converting gaseous alkanes to olefins and liquid hydrocarbons
US7244867B2 (en) 2004-04-16 2007-07-17 Marathon Oil Company Process for converting gaseous alkanes to liquid hydrocarbons
WO2007092410A2 (en) 2006-02-03 2007-08-16 Grt, Inc. Separation of light gases from halogens
EP1993979A4 (en) 2006-02-03 2011-07-06 Grt Inc CONTINUOUS PROCESS FOR CONVERTING NATURAL GAS TO LIQUID HYDROCARBONS
US8921625B2 (en) 2007-02-05 2014-12-30 Reaction35, LLC Continuous process for converting natural gas to liquid hydrocarbons
US7998438B2 (en) 2007-05-24 2011-08-16 Grt, Inc. Zone reactor incorporating reversible hydrogen halide capture and release
US8282810B2 (en) 2008-06-13 2012-10-09 Marathon Gtf Technology, Ltd. Bromine-based method and system for converting gaseous alkanes to liquid hydrocarbons using electrolysis for bromine recovery
US8198495B2 (en) 2010-03-02 2012-06-12 Marathon Gtf Technology, Ltd. Processes and systems for the staged synthesis of alkyl bromides
US8367884B2 (en) 2010-03-02 2013-02-05 Marathon Gtf Technology, Ltd. Processes and systems for the staged synthesis of alkyl bromides
US8815050B2 (en) 2011-03-22 2014-08-26 Marathon Gtf Technology, Ltd. Processes and systems for drying liquid bromine
US8436220B2 (en) 2011-06-10 2013-05-07 Marathon Gtf Technology, Ltd. Processes and systems for demethanization of brominated hydrocarbons
US8829256B2 (en) 2011-06-30 2014-09-09 Gtc Technology Us, Llc Processes and systems for fractionation of brominated hydrocarbons in the conversion of natural gas to liquid hydrocarbons
US8802908B2 (en) 2011-10-21 2014-08-12 Marathon Gtf Technology, Ltd. Processes and systems for separate, parallel methane and higher alkanes' bromination
US9193641B2 (en) 2011-12-16 2015-11-24 Gtc Technology Us, Llc Processes and systems for conversion of alkyl bromides to higher molecular weight hydrocarbons in circulating catalyst reactor-regenerator systems
CN111440194A (zh) * 2020-04-22 2020-07-24 华南农业大学 一种阿莫西林衍生物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE49880B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide

Also Published As

Publication number Publication date
YU61782A (en) 1985-03-20
GB2095249A (en) 1982-09-29
PL131262B1 (en) 1984-10-31
DD202578A5 (de) 1983-09-21
GR76479B (da) 1984-08-10
ES510657A0 (es) 1983-04-16
AR231297A1 (es) 1984-10-31
DK159159B (da) 1990-09-10
DK126882A (da) 1982-09-24
IL65305A0 (en) 1982-05-31
NO159660B (no) 1988-10-17
EP0061281A1 (en) 1982-09-29
KR830009109A (ko) 1983-12-17
CA1178575A (en) 1984-11-27
YU42760B (en) 1988-12-31
NO820896L (no) 1982-09-24
ES8403136A1 (es) 1984-03-01
ES518997A0 (es) 1984-03-01
IL65305A (en) 1985-02-28
RO86859B (ro) 1985-05-31
PL239265A1 (en) 1983-06-06
RO83699A (ro) 1984-03-15
SU1122229A3 (ru) 1984-10-30
FI74018B (fi) 1987-08-31
CS228537B2 (en) 1984-05-14
PL130553B1 (en) 1984-08-31
IE820655L (en) 1982-09-23
KR850001630B1 (ko) 1985-10-31
AU8176282A (en) 1982-11-04
EP0061281B1 (en) 1984-11-07
PT74623A (en) 1982-04-01
NO159660C (no) 1989-01-25
IN157669B (da) 1986-05-17
RO86859A (ro) 1985-05-20
ES8305770A1 (es) 1983-04-16
BG39113A3 (en) 1986-04-15
IE52653B1 (en) 1988-01-06
FI74018C (fi) 1987-12-10
EG15802A (en) 1987-03-30
PT74623B (en) 1984-11-26
FI820995L (fi) 1982-09-24
PL235275A1 (en) 1983-04-11
AU527916B2 (en) 1983-03-31
DE3261166D1 (en) 1984-12-13
BG39297A3 (en) 1986-05-15
RO83699B (ro) 1984-03-30

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