ES8302780A1 - Un procedimiento para la determinacion de enzimas. - Google Patents
Un procedimiento para la determinacion de enzimas.Info
- Publication number
- ES8302780A1 ES8302780A1 ES499343A ES499343A ES8302780A1 ES 8302780 A1 ES8302780 A1 ES 8302780A1 ES 499343 A ES499343 A ES 499343A ES 499343 A ES499343 A ES 499343A ES 8302780 A1 ES8302780 A1 ES 8302780A1
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- tripeptidic
- enzymes
- splitted
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 5
- 108090000790 Enzymes Proteins 0.000 title abstract 5
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010504 bond cleavage reaction Methods 0.000 abstract 1
- 230000005518 electrochemistry Effects 0.000 abstract 1
- 230000007071 enzymatic hydrolysis Effects 0.000 abstract 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000005375 photometry Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 238000002798 spectrophotometry method Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/10—Anilides
- C12Q2337/12—Para-Nitroanilides p-NA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/20—Coumarin derivatives
- C12Q2337/22—7-Amino-4-methylcoumarin, i.e. AMC, MCA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96444—Factor X (3.4.21.6)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/802—Chromogenic or luminescent peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/28—Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/106664—Blood serum or blood plasma standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/109163—Inorganic standards or controls
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Saccharide Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA DETERMINACION DE ENZIMAS, ESPECIALMENTE LA DETERMINACION CUANTITATIVA DEL FACTOR X<033> EN UN MEDIO QUE CONTENGA, EN EL QUE SE PRODUZCA O CONSUMA FACTOR X<033>. CONSISTE EN LA REACCION DE DICHO MEDIO CON UN DERIVADO DE TRIPEPTIDO DE FORMULA (I), EN LA QUE R Y R PUEDEN SER VARIOS TIPOS DE RADICALES; R ES HIDROGENO O ALCOHILO C <003> ; R ES HIDROGENO, METILO O ETILO; Y R ES AMINO SUSTITUIDO CON RADICALES AROMATICOS O HETEROCICLICOS, SEPARABLE POR VIA HIDROLITICA; DE MODO QUE SE FORMA UN COMPUESTO HR COLOREADO O FLUORESCENTE O UNA SAL DEL MISMO, CUYA CANTIDAD LIBERADA POR LA ACCION CATALITICA DEL FACTOR X<033> PUEDE SER DETERMINADA POR ALGUN METODO ESPECTROSCOPICO. ESTE PROCEDIMIENTO TIENE APLICACION PARA LA DETERMINACION DEL FACTOR X<033> EN EL PLASMA SANGUINEO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH113080 | 1980-02-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES499343A0 ES499343A0 (es) | 1983-01-16 |
ES8302780A1 true ES8302780A1 (es) | 1983-01-16 |
Family
ID=4203192
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES499343A Expired ES8302780A1 (es) | 1980-02-12 | 1981-02-11 | Un procedimiento para la determinacion de enzimas. |
Country Status (13)
Country | Link |
---|---|
US (2) | US4440678A (es) |
EP (1) | EP0034122B1 (es) |
JP (2) | JPH032879B2 (es) |
AT (1) | ATE4702T1 (es) |
AU (1) | AU581050B2 (es) |
CA (1) | CA1161432A (es) |
DE (1) | DE3160903D1 (es) |
DK (1) | DK154221C (es) |
ES (1) | ES8302780A1 (es) |
IL (1) | IL62096A (es) |
NO (1) | NO151787C (es) |
WO (1) | WO1981002294A1 (es) |
ZA (1) | ZA81789B (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3244030A1 (de) * | 1982-11-27 | 1984-05-30 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung |
JPS59112952A (ja) * | 1982-12-21 | 1984-06-29 | Taisho Pharmaceut Co Ltd | ペプチド誘導体 |
DE3311287A1 (de) * | 1983-03-28 | 1984-10-04 | Behringwerke Ag, 3550 Marburg | Verfahren zur fotometrischen bestimmung der aktivierten partiellen thromboplastinzeit und reagenz dazu |
DE3484912D1 (de) * | 1983-06-03 | 1991-09-19 | Pentapharm Ag | Peptidderivate und deren verwendung als substrate zur quantitativen bestimmung von enzymen. |
JPS60241900A (ja) * | 1984-05-16 | 1985-11-30 | Nitto Boseki Co Ltd | 新規な第Xa因子活性測定用基質 |
DE3504405A1 (de) * | 1985-02-08 | 1986-08-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Bestimmung von prokallikrein |
GB8504522D0 (en) * | 1985-02-21 | 1985-03-27 | Genetics Int Inc | Electrochemistry of mediators |
FI860043A (fi) * | 1986-01-06 | 1987-07-07 | Orion Yhtymae Oy | Peptidsubstrat samt foerfarande foer kvantitativ analys av endotoxin. |
SE8601327D0 (sv) * | 1986-03-21 | 1986-03-21 | Kabivitrum Ab | Nya peptidderivat |
SE461494B (sv) * | 1986-03-21 | 1990-02-19 | Thorsman & Co Ab | Faestanordning foer en elektrisk kopplingsdosa |
DE3783966T2 (de) * | 1986-07-29 | 1993-05-27 | Sunstar Inc | Reagens zur pruefung von periodentalen erkrankungen. |
DE3629175A1 (de) * | 1986-08-28 | 1988-03-17 | Behringwerke Ag | Chromogene verbindungen, verfahren zu deren herstellung und ihre verwendung |
US5110727A (en) * | 1987-04-03 | 1992-05-05 | Cardiovascular Diagnostics, Inc. | Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles |
US5115099A (en) * | 1988-06-14 | 1992-05-19 | Nitto Boseki Co., Ltd. | Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates |
JPH06104079B2 (ja) * | 1988-07-14 | 1994-12-21 | 日東紡績株式会社 | 新規な酵素活性測定用基質 |
EP0436654A1 (en) | 1988-09-30 | 1991-07-17 | The University Of Vermont And State Agricultural College | Immunoassays for catalytically-active, serine proteases |
US5320945A (en) * | 1989-07-14 | 1994-06-14 | Boehringer Mannheim Gmbh | Method and reagent for the determination of antithrombin III |
DE69022019T2 (de) * | 1989-08-17 | 1996-05-02 | Baxter Diagnostics Inc | Faktor-ix chromogenisches assay. |
FR2658519B1 (fr) * | 1990-02-19 | 1995-07-07 | Serbio | Substrats peptidiques pour identification du facteur xa. |
US6348570B1 (en) * | 1991-08-16 | 2002-02-19 | Merck & Co., Inc. | Chromophore containing compounds and their use in determining interleukin-1β convertase activity |
US5308756A (en) * | 1991-11-20 | 1994-05-03 | Baxter Diagnostics Inc. | Protein S chromogenic assay |
TR199900947T2 (xx) * | 1996-10-31 | 1999-07-21 | Roche Diagnostics Gmbh | IXa fakt�r�n�n katalitik aktivitesinin belirlenmesi y�ntemi. |
US6297024B1 (en) | 1998-10-15 | 2001-10-02 | Cell Activation, Inc. | Methods for assessing complement activation |
US6235494B1 (en) | 1999-02-08 | 2001-05-22 | The Scripps Research Institute | Substrates for assessing mannan-binding protein-associated serine protease activity and methods using the substrates |
WO2000050446A1 (de) * | 1999-02-23 | 2000-08-31 | Pentapharm Ag | Oligopeptidderivate zur elektrochemischen messung der aktivität von proteasen |
EP1425296B1 (de) * | 2001-09-10 | 2011-04-13 | Novel Science International GmbH | Organische verbindungen mit biologischer wirkung als thrombinhemmer und ihre verwendung |
DE102005003145B4 (de) | 2005-01-21 | 2006-10-19 | Dade Behring Marburg Gmbh | Stablies, chromogenes Flüssigreagenz und dessen Verwendung in gerinnungsdiagnostischen Tests |
US8941631B2 (en) | 2007-11-16 | 2015-01-27 | Qualcomm Mems Technologies, Inc. | Simultaneous light collection and illumination on an active display |
EP2333555A1 (de) | 2009-12-09 | 2011-06-15 | Siemens Healthcare Diagnostics Products GmbH | Heterogener Gerinnungstest |
EP2465941A1 (de) | 2010-12-20 | 2012-06-20 | Siemens Healthcare Diagnostics Products GmbH | Verfahren zur simultanen Bestimmung mehrerer Gerinnungsproteasen |
EP2484775A1 (de) | 2011-02-07 | 2012-08-08 | Siemens Healthcare Diagnostics Products GmbH | Heparin-insensitives Verfahren zur Bestimmung von direkten Gerinnungsfaktorinhibitoren |
EP2843416A1 (de) | 2013-09-02 | 2015-03-04 | Siemens Healthcare Diagnostics Products GmbH | Kontroll- und Kalibratormaterial für die Bestimmung von direkten Antikoagulanzien |
EP3348649A1 (de) | 2017-01-16 | 2018-07-18 | Siemens Healthcare Diagnostics Products GmbH | Universales kontrollmaterial für gerinnungsfaktorinhibitor-teste |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE380258B (sv) * | 1972-05-02 | 1975-11-03 | Bofors Ab | Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser |
US4162941A (en) * | 1974-12-05 | 1979-07-31 | Ab Kabi | Method for determining a proteolytic enzyme |
SE407058B (sv) * | 1974-12-05 | 1979-03-12 | Kabi Ab | Nya kromogena enzymsubstrat for serinproteaser |
CH622286A5 (es) * | 1975-06-23 | 1981-03-31 | Pentapharm Ag | |
SE407571B (sv) * | 1975-07-11 | 1979-04-02 | Kabi Ab | Nya kromogena enzymsubstrat for serinproteaser |
US4061625A (en) * | 1975-07-11 | 1977-12-06 | Ab Kabi | Novel chromogenic thrombin substrates |
US4137225A (en) * | 1975-07-11 | 1979-01-30 | Ab Kabi | Novel chromogenic enzyme substrates |
SE419871B (sv) * | 1975-12-01 | 1981-08-31 | Pharmacia Ab | Sett att bestemma aktiviteten hos faktor xa-inhibitor i blod |
CH634662A5 (de) * | 1976-05-28 | 1983-02-15 | Pentapharm Ag | Verwendung von tripeptidderivaten zur quantitativen bestimmung von plasminogen-aktivatoren. |
SE437153B (sv) * | 1976-12-01 | 1985-02-11 | Kabi Ab | Specifika kromogena enzymsubstrat for serinproteaser |
SE7801373L (sv) * | 1978-02-07 | 1979-08-08 | Kabi Ab | Lett spjelkbara substrat for kvantifiering av proteaser |
US4275153A (en) * | 1978-08-03 | 1981-06-23 | American Hospital Supply Corporation | Analytical fluorogenic substrates for proteolytic enzymes |
US4229540A (en) * | 1979-07-02 | 1980-10-21 | Cutter Laboratories, Inc. | Hydrolase purified from human plasma |
-
1981
- 1981-02-05 CA CA000370232A patent/CA1161432A/en not_active Expired
- 1981-02-06 ZA ZA00810789A patent/ZA81789B/xx unknown
- 1981-02-06 AT AT81810036T patent/ATE4702T1/de not_active IP Right Cessation
- 1981-02-06 DE DE8181810036T patent/DE3160903D1/de not_active Expired
- 1981-02-06 US US06/302,420 patent/US4440678A/en not_active Expired - Lifetime
- 1981-02-06 JP JP56500604A patent/JPH032879B2/ja not_active Expired - Lifetime
- 1981-02-06 EP EP81810036A patent/EP0034122B1/de not_active Expired
- 1981-02-06 WO PCT/CH1981/000014 patent/WO1981002294A1/de unknown
- 1981-02-09 IL IL62096A patent/IL62096A/xx not_active IP Right Cessation
- 1981-02-11 ES ES499343A patent/ES8302780A1/es not_active Expired
- 1981-10-09 NO NO813418A patent/NO151787C/no unknown
- 1981-10-12 DK DK451981A patent/DK154221C/da not_active IP Right Cessation
-
1982
- 1982-09-15 US US06/418,257 patent/US4480030A/en not_active Expired - Lifetime
-
1985
- 1985-12-28 JP JP60299814A patent/JPS63300A/ja active Granted
-
1986
- 1986-01-13 AU AU52204/86A patent/AU581050B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JPS63300A (ja) | 1988-01-05 |
JPH032879B2 (es) | 1991-01-17 |
ATE4702T1 (de) | 1983-10-15 |
EP0034122B1 (de) | 1983-09-21 |
EP0034122A1 (de) | 1981-08-19 |
DK154221B (da) | 1988-10-24 |
NO151787B (no) | 1985-02-25 |
NO151787C (no) | 1985-06-05 |
AU5220486A (en) | 1986-05-15 |
ZA81789B (en) | 1982-03-31 |
AU581050B2 (en) | 1989-02-09 |
ES499343A0 (es) | 1983-01-16 |
DE3160903D1 (en) | 1983-10-27 |
DK451981A (da) | 1981-10-12 |
CA1161432A (en) | 1984-01-31 |
JPS56501849A (es) | 1981-12-17 |
JPH0253040B2 (es) | 1990-11-15 |
DK154221C (da) | 1989-05-22 |
US4440678A (en) | 1984-04-03 |
IL62096A0 (en) | 1981-03-31 |
NO813418L (no) | 1981-10-09 |
US4480030A (en) | 1984-10-30 |
IL62096A (en) | 1986-09-30 |
WO1981002294A1 (fr) | 1981-08-20 |
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