ES8300332A1 - Un procedimiento para la preparacion de nuevos derivados de imidazoquinazolinas - Google Patents
Un procedimiento para la preparacion de nuevos derivados de imidazoquinazolinasInfo
- Publication number
- ES8300332A1 ES8300332A1 ES504758A ES504758A ES8300332A1 ES 8300332 A1 ES8300332 A1 ES 8300332A1 ES 504758 A ES504758 A ES 504758A ES 504758 A ES504758 A ES 504758A ES 8300332 A1 ES8300332 A1 ES 8300332A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- alkyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fats And Perfumes (AREA)
- Polymerisation Methods In General (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE IMIDAZOQUINAZOLINAS, ASI COMO DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R <024>R E PUEDEN SER VARIOS TIPOS DE RADICALES; Y R Y R SON HIDROGENO O ALQUILO C <024> . CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), EN LA QUE R <024>R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); Y R ES BENCILO OPCIONALMENTE SUSTITUIDO POR ALQUILO O ALCOXILO C <024> , CON UN ACIDO; SEGUIDA DE LA SEPARACION DEL COMPUESTO RESULTANTE O DE UN TAUTOMERO. LA REACCION SE LLEVA A CABO EN PRESENCIA DE ANISOL, EMPLEANDO COMO ACIDO UNO MINERAL, TAL COMO ACIDO FOSFORICO, A UNA TEMPERATURA ENTRE LA AMBIENTE Y 150<025>C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA PREVENCION DE TROMBOSIS Y PARA EL TRATAMIENTO DE ULCERAS GASTRICAS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH619280 | 1980-08-15 | ||
| CH348381 | 1981-05-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8300332A1 true ES8300332A1 (es) | 1982-11-01 |
| ES504758A0 ES504758A0 (es) | 1982-11-01 |
Family
ID=25693125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES504758A Granted ES504758A0 (es) | 1980-08-15 | 1981-08-14 | Un procedimiento para la preparacion de nuevos derivados de imidazoquinazolinas |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4390540A (es) |
| EP (1) | EP0046267A1 (es) |
| AR (1) | AR231447A1 (es) |
| AU (1) | AU7388081A (es) |
| CA (1) | CA1162537A (es) |
| CS (1) | CS220343B2 (es) |
| DK (1) | DK316881A (es) |
| ES (1) | ES504758A0 (es) |
| FI (1) | FI812303L (es) |
| HU (1) | HU183543B (es) |
| IL (1) | IL63524A0 (es) |
| MC (1) | MC1410A1 (es) |
| NO (1) | NO812766L (es) |
| NZ (1) | NZ197966A (es) |
| PT (1) | PT73525B (es) |
| ZW (1) | ZW16481A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4455311A (en) * | 1981-08-28 | 1984-06-19 | Hoffmann-La Roche Inc. | Imidazoquinazoline derivatives which inhibit the aggregation of blood platelets, inhibit gastric secretion or have activity on the circulatory system |
| DE3422323A1 (de) * | 1983-06-17 | 1984-12-20 | Nissan Motor Co., Ltd., Yokohama, Kanagawa | Verschraubbare verbindung |
| US4837239A (en) * | 1985-08-23 | 1989-06-06 | Syntex (U.S.A.) Inc. | Cardiotonic phosphodiesterase inhibitors complexed with water soluble vitamins |
| ES2344062T5 (es) * | 2003-01-23 | 2013-04-26 | Shire Biopharmaceuticals Holdings Ireland Limited | Formulación y procedimientos para el tratamiento de la trombocitopenia |
| US7700608B2 (en) * | 2004-08-04 | 2010-04-20 | Shire Holdings Ag | Quinazoline derivatives and their use in the treatment of thrombocythemia |
| US20060030574A1 (en) * | 2004-08-04 | 2006-02-09 | Shire Holdings Ag | Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors |
| WO2007022946A1 (de) | 2005-08-21 | 2007-03-01 | Abbott Gmbh & Co. Kg | Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| US8304420B2 (en) | 2006-11-28 | 2012-11-06 | Shire Llc | Substituted quinazolines for reducing platelet count |
| US7910597B2 (en) | 2006-11-28 | 2011-03-22 | Shire Llc | Substituted quinazolines |
| WO2014089904A1 (en) | 2012-12-10 | 2014-06-19 | Abbvie Inc. | Triazinone compounds |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE794964A (fr) * | 1972-02-04 | 1973-08-02 | Bristol Myers Co | Nouveaux agents hypotenseurs et procede pour les preparer |
| US3883524A (en) * | 1972-06-08 | 1975-05-13 | Hoechst Co American | Quinazoline derivatives |
| JPS5398997A (en) * | 1977-02-09 | 1978-08-29 | Sumitomo Chem Co Ltd | Fused pyridine derivertives and process for their preparation |
| NL7807507A (nl) * | 1977-07-25 | 1979-01-29 | Hoffmann La Roche | Tricyclische verbindingen. |
| JPS5555188A (en) * | 1978-10-20 | 1980-04-22 | Sumitomo Chem Co Ltd | Tricyclic condensed pyrimidine derivative and its preparation |
| JPS5629591A (en) * | 1979-08-17 | 1981-03-24 | Dai Ichi Seiyaku Co Ltd | Tricyclic compound |
-
1981
- 1981-07-13 ZW ZW164/81A patent/ZW16481A1/xx unknown
- 1981-07-15 DK DK316881A patent/DK316881A/da not_active Application Discontinuation
- 1981-07-17 CS CS815501A patent/CS220343B2/cs unknown
- 1981-07-22 FI FI812303A patent/FI812303L/fi not_active Application Discontinuation
- 1981-07-24 CA CA000382464A patent/CA1162537A/en not_active Expired
- 1981-08-07 AU AU73880/81A patent/AU7388081A/en not_active Abandoned
- 1981-08-07 NZ NZ197966A patent/NZ197966A/en unknown
- 1981-08-07 IL IL63524A patent/IL63524A0/xx unknown
- 1981-08-11 AR AR286404A patent/AR231447A1/es active
- 1981-08-11 EP EP81106257A patent/EP0046267A1/de not_active Ceased
- 1981-08-12 MC MC811534A patent/MC1410A1/xx unknown
- 1981-08-12 US US06/292,315 patent/US4390540A/en not_active Expired - Fee Related
- 1981-08-12 HU HU812340A patent/HU183543B/hu unknown
- 1981-08-14 ES ES504758A patent/ES504758A0/es active Granted
- 1981-08-14 NO NO812766A patent/NO812766L/no unknown
- 1981-08-14 PT PT73525A patent/PT73525B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MC1410A1 (fr) | 1982-07-16 |
| NO812766L (no) | 1982-02-16 |
| US4390540A (en) | 1983-06-28 |
| CA1162537A (en) | 1984-02-21 |
| IL63524A0 (en) | 1981-11-30 |
| HU183543B (en) | 1984-05-28 |
| EP0046267A1 (de) | 1982-02-24 |
| ES504758A0 (es) | 1982-11-01 |
| FI812303L (fi) | 1982-02-16 |
| PT73525B (en) | 1983-08-16 |
| CS220343B2 (en) | 1983-03-25 |
| AR231447A1 (es) | 1984-11-30 |
| PT73525A (en) | 1981-09-01 |
| ZW16481A1 (en) | 1982-03-10 |
| DK316881A (da) | 1982-02-16 |
| AU7388081A (en) | 1982-02-18 |
| NZ197966A (en) | 1984-07-31 |
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