JPS5629591A - Tricyclic compound - Google Patents

Tricyclic compound

Info

Publication number
JPS5629591A
JPS5629591A JP10481879A JP10481879A JPS5629591A JP S5629591 A JPS5629591 A JP S5629591A JP 10481879 A JP10481879 A JP 10481879A JP 10481879 A JP10481879 A JP 10481879A JP S5629591 A JPS5629591 A JP S5629591A
Authority
JP
Japan
Prior art keywords
formula
compound
lower alkyl
solvent
platelet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10481879A
Other languages
Japanese (ja)
Other versions
JPS6247186B2 (en
Inventor
Fumiyoshi Ishikawa
Shinichiro Ashida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Priority to JP10481879A priority Critical patent/JPS5629591A/en
Publication of JPS5629591A publication Critical patent/JPS5629591A/en
Publication of JPS6247186B2 publication Critical patent/JPS6247186B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I (R1 is H or lower alkyl; R2 and R3 are H, halogen, lower alkyl, etc.; Z is optionally substituted alkylene), and an acid addition salt thereof.
EXAMPLE: 1-Methyl-1,2,3,5-tetrahydroimidazo[1,2-a]quinazolin-2-one.
USE: A medicine, having a platelet aggregation inhibitory action, and useful for preventing intravascular thrombosis, short-term local anemia and platelet thrombus in using a prosthetic apparatus, e.g. an artificial heart. Cardiotonic and hypoglycemic actions are expectable.
PROCESS: A compound of formula II (R4 is H or phenyl) is catalytically reduced in a solvent, e.g. methanol or ethanol, or a hydrous solvent thereof in the presence of HCl or hydrobromic acid and Pd-C as a catalyst. When R4 is H, the benzyl group is removed to give the titled compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP10481879A 1979-08-17 1979-08-17 Tricyclic compound Granted JPS5629591A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10481879A JPS5629591A (en) 1979-08-17 1979-08-17 Tricyclic compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10481879A JPS5629591A (en) 1979-08-17 1979-08-17 Tricyclic compound

Publications (2)

Publication Number Publication Date
JPS5629591A true JPS5629591A (en) 1981-03-24
JPS6247186B2 JPS6247186B2 (en) 1987-10-06

Family

ID=14390975

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10481879A Granted JPS5629591A (en) 1979-08-17 1979-08-17 Tricyclic compound

Country Status (1)

Country Link
JP (1) JPS5629591A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390540A (en) * 1980-08-15 1983-06-28 Hoffmann-La Roche Inc. Imidazoquinazolines having pharmaceutical activity
US4455311A (en) * 1981-08-28 1984-06-19 Hoffmann-La Roche Inc. Imidazoquinazoline derivatives which inhibit the aggregation of blood platelets, inhibit gastric secretion or have activity on the circulatory system

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390540A (en) * 1980-08-15 1983-06-28 Hoffmann-La Roche Inc. Imidazoquinazolines having pharmaceutical activity
US4455311A (en) * 1981-08-28 1984-06-19 Hoffmann-La Roche Inc. Imidazoquinazoline derivatives which inhibit the aggregation of blood platelets, inhibit gastric secretion or have activity on the circulatory system

Also Published As

Publication number Publication date
JPS6247186B2 (en) 1987-10-06

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