JPS5555188A - Tricyclic condensed pyrimidine derivative and its preparation - Google Patents

Tricyclic condensed pyrimidine derivative and its preparation

Info

Publication number
JPS5555188A
JPS5555188A JP12981178A JP12981178A JPS5555188A JP S5555188 A JPS5555188 A JP S5555188A JP 12981178 A JP12981178 A JP 12981178A JP 12981178 A JP12981178 A JP 12981178A JP S5555188 A JPS5555188 A JP S5555188A
Authority
JP
Japan
Prior art keywords
lower alkyl
pyrimidine derivative
compound
tricyclic condensed
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12981178A
Other languages
Japanese (ja)
Inventor
Michihiro Yamamoto
Masao Koshiba
Hisao Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP12981178A priority Critical patent/JPS5555188A/en
Publication of JPS5555188A publication Critical patent/JPS5555188A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NEW MATERIAL:A tricyclic condensed pyrimidine derivative of formula I (R1W3 are H, halogen, lower alkyl, etc.; R4 is H or lower alkyl; R5 is lower alkyl; A is C=C, C=N, or N=N, provided that one of the C atoms may be substituted by lower alkyl group) and its acid addition salt.
EXAMPLE: 4,5-Dihydro-4-etyl-5-hydroxy-5-phentyltetrazolo[1,5-a]quinazoline.
USE: Anti-phlogistic, analgesic agent.
PROCESS: The compound I can be prepared, e.g. by (1) reacting a compound II with a compound III [W is Li or MgX (X is halogen)] in an inert solvent at a temperature between room temperature and the refluxing temperature of the solvent, and (2) reacting the reaction mixture with water or a lower alkanol under cooling.
COPYRIGHT: (C)1980,JPO&Japio
JP12981178A 1978-10-20 1978-10-20 Tricyclic condensed pyrimidine derivative and its preparation Pending JPS5555188A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12981178A JPS5555188A (en) 1978-10-20 1978-10-20 Tricyclic condensed pyrimidine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12981178A JPS5555188A (en) 1978-10-20 1978-10-20 Tricyclic condensed pyrimidine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5555188A true JPS5555188A (en) 1980-04-22

Family

ID=15018798

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12981178A Pending JPS5555188A (en) 1978-10-20 1978-10-20 Tricyclic condensed pyrimidine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5555188A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390540A (en) * 1980-08-15 1983-06-28 Hoffmann-La Roche Inc. Imidazoquinazolines having pharmaceutical activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4390540A (en) * 1980-08-15 1983-06-28 Hoffmann-La Roche Inc. Imidazoquinazolines having pharmaceutical activity

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