ES8207537A1 - Procedimiento de preparacion de imidazo (1,2-a)piridinas - Google Patents

Procedimiento de preparacion de imidazo (1,2-a)piridinas

Info

Publication number
ES8207537A1
ES8207537A1 ES506412A ES506412A ES8207537A1 ES 8207537 A1 ES8207537 A1 ES 8207537A1 ES 506412 A ES506412 A ES 506412A ES 506412 A ES506412 A ES 506412A ES 8207537 A1 ES8207537 A1 ES 8207537A1
Authority
ES
Spain
Prior art keywords
hydrogen
radical
image
alkyl radical
halogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506412A
Other languages
English (en)
Spanish (es)
Other versions
ES506412A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9247171&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8207537(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES506412A0 publication Critical patent/ES506412A0/es
Publication of ES8207537A1 publication Critical patent/ES8207537A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES506412A 1980-10-22 1981-10-21 Procedimiento de preparacion de imidazo (1,2-a)piridinas Expired ES8207537A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8022537A FR2492382A1 (fr) 1980-10-22 1980-10-22 Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES506412A0 ES506412A0 (es) 1982-09-16
ES8207537A1 true ES8207537A1 (es) 1982-09-16

Family

ID=9247171

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506412A Expired ES8207537A1 (es) 1980-10-22 1981-10-21 Procedimiento de preparacion de imidazo (1,2-a)piridinas

Country Status (22)

Country Link
US (2) US4382938A (OSRAM)
EP (1) EP0050563B1 (OSRAM)
JP (1) JPS5798283A (OSRAM)
AT (1) ATE7393T1 (OSRAM)
AU (1) AU544345B2 (OSRAM)
CA (1) CA1157470A (OSRAM)
DE (1) DE3163524D1 (OSRAM)
DK (1) DK154429C (OSRAM)
ES (1) ES8207537A1 (OSRAM)
FI (1) FI71143C (OSRAM)
FR (1) FR2492382A1 (OSRAM)
GR (1) GR74701B (OSRAM)
IE (1) IE51686B1 (OSRAM)
IL (1) IL64091A (OSRAM)
LU (1) LU88228I2 (OSRAM)
MX (1) MX6463E (OSRAM)
NL (1) NL930044I2 (OSRAM)
NO (1) NO155664C (OSRAM)
NZ (1) NZ198722A (OSRAM)
OA (1) OA07076A (OSRAM)
PT (1) PT73863B (OSRAM)
ZA (1) ZA817297B (OSRAM)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525602A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2525601A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2568879B1 (fr) * 1984-08-07 1986-12-12 Synthelabo Imidazo(1,2-a)quinolines, leur preparation et leur application en therapeutique
FR2581646B1 (fr) * 1985-05-07 1987-09-18 Synthelabo Derives d'imidazopyridine, leur preparation et leur application en therapeutique
FR2593179B1 (fr) * 1986-01-22 1988-04-01 Synthelabo Derives d'imidazo(1,2-a)quinoleines, leur preparation et leur application en therapeutique
ES2032455T3 (es) * 1986-01-22 1993-02-16 Synthelabo Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas.
FR2593817B1 (fr) * 1986-01-31 1988-04-15 Synthelabo Derives de tetrahydro-5,6,7,8 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
FR2599368B1 (fr) * 1986-06-02 1988-08-05 Synthelabo Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique
FR2600650B1 (fr) * 1986-06-27 1988-09-09 Synthelabo Procede de preparation d'imidazopyridines et composes intermediaires
FR2606410B1 (fr) * 1986-11-07 1989-02-24 Synthelabo Imidazopyridines, leur preparation et leur application en therapeutique
FR2606411B1 (fr) * 1986-11-07 1989-04-07 Synthelabo Imidazopyridine-acetamides, leur preparation et leur application en therapeutique
FR2606409B1 (fr) * 1986-11-07 1989-05-05 Synthelabo Derives d'imidazopyridine, leur preparation et leur application en therapeutique
FR2612928B1 (fr) * 1987-03-27 1989-06-16 Synthelabo Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique
DE3865073D1 (de) * 1987-03-27 1991-10-31 Synthelabo Imidazopyridinderivate, ihre herstellung und therapeutische verwendung.
FR2612927B1 (fr) * 1987-03-27 1989-06-09 Synthelabo Derives d'imidazopyridines, leur preparation et leur application en therapeutique
US5032595A (en) * 1989-11-24 1991-07-16 Fidia-Georgetown Institute For The Neurosciences Method of stimulating steroidogenesis with alpidem
WO1996025414A1 (en) * 1995-02-15 1996-08-22 Pharmacia & Upjohn Company Imidazo[1,2-a]pyridines for the treatment of cns and cardiac diseases
IT1276522B1 (it) * 1995-04-07 1997-10-31 Elena Benincasa Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
AUPP278498A0 (en) 1998-04-03 1998-04-30 Australian Nuclear Science & Technology Organisation Peripheral benzodiazepine receptor binding agents
EP1005863A1 (en) * 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof
ES2195510T3 (es) * 1999-03-25 2003-12-01 Synthon Bv Derivados de imidazopiridina y procedimiento para prepararlos.
PT1163241E (pt) * 1999-03-25 2005-08-31 Synthon Bv Sais de zolpidem
US6333345B1 (en) 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
EP1272181A2 (en) * 2000-04-13 2003-01-08 Synthon B.V. Modified release formulations containing a hypnotic agent
EP1604663A1 (en) 2000-04-24 2005-12-14 Teva Pharmaceutical Industries Ltd Zolpidem Hemitartrate Form H Solvate
IL152411A0 (en) * 2000-04-24 2003-05-29 Teva Pharma Zolpidem hemitartrate
WO2001092257A1 (en) * 2000-05-26 2001-12-06 Neurogen Corporation Oxo-imidazopyrimidine-carboxamides and their use as gaba brain receptor ligands
AU2001270297A1 (en) 2000-06-30 2002-01-14 Neurogen Corporation 2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands
IT1318624B1 (it) 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
US6514969B2 (en) * 2000-08-16 2003-02-04 Boehringer Ingelheim Pharma Kg β-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions
DE10040016A1 (de) * 2000-08-16 2002-02-28 Boehringer Ingelheim Pharma Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
AU2000264428A1 (en) * 2000-08-17 2002-02-25 Cilag A.G. Process for the preparation of imidazopyridines
US6921839B2 (en) * 2000-08-29 2005-07-26 Ranbaxy Laboratories Limited Synthesis of N,N-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
DE10117183A1 (de) * 2001-04-05 2002-10-10 Gruenenthal Gmbh Verwendung von substituierten Imidazo[1,2-a]-pyridinverbindungen als Arzneimittel
KR100433502B1 (ko) * 2001-10-10 2004-06-07 철 양 확장부가 형성된 종이컵
DE10247271A1 (de) * 2002-10-10 2004-08-26 Grünenthal GmbH Substituierte C-Imidazo[1,2-a]pyridin-3-yle
CA2509561A1 (en) * 2002-12-18 2004-07-15 Mallinckrodt Inc. Synthesis of heteroaryl acetamides
WO2004066930A2 (en) * 2003-01-27 2004-08-12 Arthur Zaks Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
WO2005010002A1 (en) * 2003-07-31 2005-02-03 Ranbaxy Laboratories Limited Process for the synthesis of zolpidem
EP1682549B1 (en) * 2003-10-28 2010-09-22 Sepracor Inc. Imidazo[1,2-a]pyridine anxiolytics
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
JP5179757B2 (ja) * 2004-02-17 2013-04-10 トランセプト ファーマシューティカルズ， インコーポレイティド 口腔粘膜を介して催眠剤をデリバリーするための組成物及びその使用方法
US20050267176A1 (en) 2004-02-18 2005-12-01 Sepracor Inc. Dopamine-agonist combination therapy for improving sleep quality
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
US20060084806A1 (en) * 2004-07-21 2006-04-20 Ramasubramanian Sridharan Processes for the preparation of imidazo[1,2-a] pyridine derivatives
FR2874611B1 (fr) * 2004-08-31 2006-11-17 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20070123562A1 (en) * 2005-05-25 2007-05-31 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the-night insomnia
US20070225322A1 (en) * 2005-05-25 2007-09-27 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the night insomnia
US20070287740A1 (en) * 2005-05-25 2007-12-13 Transcept Pharmaceuticals, Inc. Compositions and methods of treating middle-of-the night insomnia
US20070020333A1 (en) * 2005-07-20 2007-01-25 Chin-Chih Chiang Controlled release of hypnotic agents
EP1928437A2 (en) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
WO2007065559A1 (en) 2005-11-18 2007-06-14 Synthon B.V. Zolpidem tablets
EP1803722A1 (en) 2006-01-03 2007-07-04 Ferrer Internacional, S.A. Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof
US8309104B2 (en) * 2006-03-02 2012-11-13 Watson Pharmaceuticals, Inc. Oral controlled release formulation for sedative and hypnotic agents
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP1845098A1 (en) * 2006-03-29 2007-10-17 Ferrer Internacional, S.A. Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US7772248B2 (en) * 2006-06-05 2010-08-10 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted imidazopyridine compounds with hypnotic effects
CA2660169A1 (en) * 2006-08-24 2008-02-28 Australian Nuclear Science & Technology Organisation Fluorinated ligands for targeting peripheral benzodiazepine receptors
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
US20090076066A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched zolpidem
CN101903381A (zh) * 2007-10-24 2010-12-01 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物
US20090169618A1 (en) * 2007-12-26 2009-07-02 Limor Ari-Pardo Zolpidem pharmaceutical compositions
AU2009284695A1 (en) * 2008-08-19 2010-02-25 The University Of Sydney Novel compounds and their uses in diagnosis
US10478438B2 (en) 2008-10-16 2019-11-19 David Reed Helton Treatment of organophosphate exposure with ocinaplon
US8555875B2 (en) * 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2010122576A1 (en) 2009-04-20 2010-10-28 Matrix Laboratories Ltd Improved process for the preparation of 6-methyl-2-[4-methyl phenyl] imidazo [1, 2-a] pyridine-3-n, n-dimethyl acetamide.
JP5433508B2 (ja) * 2009-06-25 2014-03-05 高田製薬株式会社 ゾルピデム酒石酸塩含有内用液剤
CN102234275B (zh) * 2010-04-27 2015-12-16 溧阳合誉药物科技有限公司 治疗失眠的氘代咪唑并[1,2-a]吡啶衍生物、制备方法及其应用
WO2012064349A1 (en) 2010-11-09 2012-05-18 Forest Carl A Sleep aid composition and method
WO2015011722A2 (en) * 2013-07-22 2015-01-29 3A Chemie Private Limited Zolpidem, method of preparation and an intermediate therein
EP3239150B1 (en) 2014-12-24 2020-02-05 Takeda Pharmaceutical Company Limited Heterocyclic compound
EP3468545A4 (en) 2016-06-08 2020-07-22 President and Fellows of Harvard College METHODS AND COMPOSITIONS FOR REDUCING TACTILE DYSFUNCTION AND ANXIETY ASSOCIATED WITH AUTISM SPECTRUM DISORDER, RETT SYNDROME AND FRAGILE X SYNDROME
TW202003519A (zh) * 2018-03-28 2020-01-16 日商武田藥品工業股份有限公司 雜環化合物及其用途
AU2019272778B2 (en) 2018-05-22 2024-10-03 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
EP3801512A4 (en) * 2018-05-29 2022-01-19 President and Fellows of Harvard College COMPOSITIONS AND METHODS TO REDUCE TACTILE DYSFUNCTION, ANXIETY AND SOCIAL DISABILITIES
WO2020198275A1 (en) 2019-03-25 2020-10-01 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
JP2021050161A (ja) 2019-09-25 2021-04-01 武田薬品工業株式会社 複素環化合物及びその用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3336194A (en) * 1963-04-30 1967-08-15 Merck & Co Inc Indolyl acid amides
GB1076089A (en) * 1965-11-09 1967-07-19 Selvi & C Lab Bioterapico New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof

Also Published As

Publication number Publication date
ES506412A0 (es) 1982-09-16
NO155664B (no) 1987-01-26
DK154429B (da) 1988-11-14
IE51686B1 (en) 1987-02-04
FI71143C (fi) 1986-11-24
IL64091A (en) 1984-12-31
EP0050563B1 (fr) 1984-05-09
JPS637545B2 (OSRAM) 1988-02-17
PT73863B (fr) 1983-11-07
NZ198722A (en) 1984-10-19
LU88228I2 (OSRAM) 1994-02-03
FR2492382A1 (fr) 1982-04-23
NL930044I2 (nl) 1993-09-16
AU544345B2 (en) 1985-05-23
NO813551L (no) 1982-04-23
DK154429C (da) 1989-04-17
NL930044I1 (nl) 1993-08-02
IE812470L (en) 1982-04-22
MX6463E (es) 1985-06-06
DK465181A (da) 1982-04-23
FI813288L (fi) 1982-04-23
DE3163524D1 (en) 1984-06-14
ATE7393T1 (de) 1984-05-15
IL64091A0 (en) 1982-01-31
US4382938A (en) 1983-05-10
GR74701B (OSRAM) 1984-07-04
ZA817297B (en) 1982-09-29
EP0050563A1 (fr) 1982-04-28
FR2492382B1 (OSRAM) 1983-07-29
JPS5798283A (en) 1982-06-18
OA07076A (fr) 1984-01-31
NO155664C (no) 1987-05-06
PT73863A (fr) 1981-11-01
AU7668781A (en) 1983-04-28
CA1157470A (en) 1983-11-22
FI71143B (fi) 1986-08-14
US4460592A (en) 1984-07-17

Similar Documents

Publication Publication Date Title
ES8207537A1 (es) Procedimiento de preparacion de imidazo (1,2-a)piridinas
DE3367918D1 (en) Imidazo(1,2-a)pyridines, their preparation and therapeutical use
NZ304107A (en) Use of imidazo[1,2-a]pyridine-3-acetamide derivatives for treating neuropsychiatric disorders
PL263885A1 (en) Method of obtaining novel derivatives of dihydrobenzofurane and chromate carbonamide
NO159794C (no) Analogifremgangsm te ved fremstilling av terapeutisk virksomme 7-substituerte theofyllinderivater.
DE3471657D1 (en) Substituted phenyl-2-(1h)-pyrimidinones, process for their preparation and their use, and preparations containing these compounds
ATE42292T1 (de) Imidazo(1,2-c)pyrimidine und ihre salze, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und diese enthaltende zubereitungen.
ES8300116A1 (es) Procedimiento para la obtencion de nuevos derivados de la tiazolo (3,2-a)pirimidina
GR80358B (en) Substituted pyrido (1,2-c) imidazo (1,2-a) benzimidazole, method for the preparation thereof, the use thereof, pharmaceutical preparations based on said compounds
EP0115920A3 (en) Pyrazino(2',3'-3,4)pyrido(1,2-a) indole derivatives

Legal Events

Date Code Title Description
PC1A Transfer granted
GD1A Contractual licences

Effective date: 20020307