ES8203844A1 - Un procedimiento para preparar derivados de aminofenilpiri- dina - Google Patents

Un procedimiento para preparar derivados de aminofenilpiri- dina

Info

Publication number
ES8203844A1
ES8203844A1 ES502493A ES502493A ES8203844A1 ES 8203844 A1 ES8203844 A1 ES 8203844A1 ES 502493 A ES502493 A ES 502493A ES 502493 A ES502493 A ES 502493A ES 8203844 A1 ES8203844 A1 ES 8203844A1
Authority
ES
Spain
Prior art keywords
propanoyl
alpha
hydrogen
methyl
attached
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502493A
Other languages
English (en)
Other versions
ES502493A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ES8203844A1 publication Critical patent/ES8203844A1/es
Publication of ES502493A0 publication Critical patent/ES502493A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR DERIVADOS DE AMINOFENILPIRIDINA. CONSISTE EN HACER REACCIONAR UNA 4-(4-(03)-AMINOFENIL)-2-R2-3-R3-5-R5-6R6-PIRIDINA CORRESPONDIENTE CON UN AGENTE DE ACILACION QUE PROPORCIONE AC''. SE OBTIENE EL COMPUESTO (I), QUE, SI SE DESEA, SE TRANSFORMA EN LA SAL DE ADICION DE ACIDO. R ES HIDROGENO, METILO O ETILO; R3 Y R5 SON CADA UNO HIDROGENO O METILO, Y AC'' ES HIDROXIACETILO, ACETOXIACETILO, ALFA-HIDROXIPROPIONILO, METOXIACETILO, 2-BUTENOILO O CARBAMILO.
ES502493A 1980-05-27 1981-05-26 Un procedimiento para preparar derivados de aminofenilpiri- dina Granted ES502493A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/152,991 US4317827A (en) 1980-05-27 1980-05-27 4-[4(or 3)-Acylaminophenyl]pyridines and their use as cardiotonics

Publications (2)

Publication Number Publication Date
ES8203844A1 true ES8203844A1 (es) 1982-04-01
ES502493A0 ES502493A0 (es) 1982-04-01

Family

ID=22545324

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502493A Granted ES502493A0 (es) 1980-05-27 1981-05-26 Un procedimiento para preparar derivados de aminofenilpiri- dina

Country Status (22)

Country Link
US (1) US4317827A (es)
JP (1) JPS5711965A (es)
AR (1) AR228155A1 (es)
AT (1) ATA238481A (es)
AU (1) AU7090181A (es)
BE (1) BE888963A (es)
CA (1) CA1161440A (es)
DE (1) DE3120954A1 (es)
DK (1) DK229881A (es)
ES (1) ES502493A0 (es)
FI (1) FI811576L (es)
FR (2) FR2483233A1 (es)
GB (1) GB2076815B (es)
IL (1) IL62929A0 (es)
IT (1) IT1137232B (es)
LU (1) LU83396A1 (es)
NL (1) NL8102582A (es)
NO (1) NO811783L (es)
NZ (1) NZ197155A (es)
PT (1) PT73083B (es)
SE (1) SE8103325L (es)
ZA (1) ZA813474B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448780A (en) * 1982-09-03 1984-05-15 Sterling Drug Inc. N-(Lower-alkyl)-N'-[5-(pyridinyl)-2-pyridinyl]ureas and cardiotonic use thereof
US5580883A (en) * 1990-03-26 1996-12-03 Takeda Chemical Industries, Ltd. Aminobenzene compounds to prevent nerve cell degradation
US6458018B1 (en) 1999-04-23 2002-10-01 3M Innovative Properties Company Abrasive article suitable for abrading glass and glass ceramic workpieces
CA2620818A1 (en) * 2005-09-02 2007-03-08 Astellas Pharma Inc. Amide derivatives as rock inhibitors
WO2015006100A1 (en) * 2013-07-08 2015-01-15 Bristol-Myers Squibb Company Aryl amide kinase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US445493A (en) * 1891-01-27 William boyrer
US3907798A (en) * 1966-06-15 1975-09-23 Sterling Drug Inc Preparation of 4H-pyrido{8 1,2-a{9 pyrimidin-4-ones from cyclic alkylidene 2-pyridylaminomethylenemalonates
GB1183046A (en) * 1966-06-28 1970-03-04 Allen & Hanburys Ltd Novel Heterocyclic Compounds
US3753993A (en) * 1971-05-17 1973-08-21 Sterling Drug Inc 1,4-dihydro-4-oxo-7-pyridyl-3-quinoline-carboxylic acid derivatives
BE791864A (fr) * 1971-12-24 1973-03-16 Dufour Claude Nouveaux composes a fonction amide derives de la pyridine et leur preparation
JPS52125176A (en) * 1976-04-09 1977-10-20 Sterling Drug Inc Production of substituted quinoline carboxylic acid and intermediate using same

Also Published As

Publication number Publication date
CA1161440A (en) 1984-01-31
DK229881A (da) 1981-11-28
SE8103325L (sv) 1981-11-28
BE888963A (fr) 1981-11-26
FR2483233B1 (es) 1984-06-15
US4317827A (en) 1982-03-02
AR228155A1 (es) 1983-01-31
PT73083B (en) 1982-07-05
GB2076815B (en) 1984-05-23
FI811576L (fi) 1981-11-28
NO811783L (no) 1981-11-30
LU83396A1 (fr) 1982-01-20
NZ197155A (en) 1983-11-18
GB2076815A (en) 1981-12-09
DE3120954A1 (de) 1982-02-04
FR2483233A1 (fr) 1981-12-04
NL8102582A (nl) 1981-12-16
PT73083A (en) 1981-06-01
JPS5711965A (en) 1982-01-21
ATA238481A (de) 1984-01-15
FR2489147A1 (fr) 1982-03-05
AU7090181A (en) 1981-12-03
IL62929A0 (en) 1981-07-31
IT1137232B (it) 1986-09-03
ES502493A0 (es) 1982-04-01
IT8121967A0 (it) 1981-05-26
ZA813474B (en) 1982-06-30

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