ES8104405A1 - Procedimiento para preparar una vacuna de virus de gripe - Google Patents

Procedimiento para preparar una vacuna de virus de gripe

Info

Publication number
ES8104405A1
ES8104405A1 ES491517A ES491517A ES8104405A1 ES 8104405 A1 ES8104405 A1 ES 8104405A1 ES 491517 A ES491517 A ES 491517A ES 491517 A ES491517 A ES 491517A ES 8104405 A1 ES8104405 A1 ES 8104405A1
Authority
ES
Spain
Prior art keywords
influenza virus
preparing
cells
influenza
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491517A
Other languages
English (en)
Other versions
ES491517A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Cutter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21904398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8104405(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cutter Laboratories Inc filed Critical Cutter Laboratories Inc
Publication of ES491517A0 publication Critical patent/ES491517A0/es
Publication of ES8104405A1 publication Critical patent/ES8104405A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA VACUNA DE VIRUS DE GRIPE. SE INOCULA UN CULTIVO LIQUIDO DE CELULAS DE RIÑON DE PERRO CON VIRUS DE GRIPE. SE INCUBA EL CULTIVO INFECTADO EN PRESENCIA DE TRIPSINA, EN CONDICIONES SUFICIENTES PARA ASEGURAR UN DESARROLLO MAXIMO DE VIRUS Y SE COSECHA EL VIRUS DEL CULTIVO. SE ATENUA EL VIRUS COSECHADO MEDIANTE SU PASO POR EL CULTIVO CELULAR; PARA LA OBTENCION DE LA VACUNA. EXISTEN VARIANTES DE COMPOSICION Y SE PUEDE OBTENER UNA VACUNA VIRULENTA VIVA, ATENUADA O MUERTA (INACTIVA).
ES491517A 1979-05-15 1980-05-14 Procedimiento para preparar una vacuna de virus de gripe Expired ES8104405A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3923679A 1979-05-15 1979-05-15

Publications (2)

Publication Number Publication Date
ES491517A0 ES491517A0 (es) 1981-04-01
ES8104405A1 true ES8104405A1 (es) 1981-04-01

Family

ID=21904398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491517A Expired ES8104405A1 (es) 1979-05-15 1980-05-14 Procedimiento para preparar una vacuna de virus de gripe

Country Status (13)

Country Link
EP (1) EP0019218B2 (es)
JP (1) JPS55153723A (es)
AR (1) AR220838A1 (es)
AT (1) ATE16454T1 (es)
AU (1) AU535804B2 (es)
CA (1) CA1122527A (es)
DE (1) DE3071225D1 (es)
DK (1) DK154749C (es)
ES (1) ES8104405A1 (es)
IL (1) IL60063A0 (es)
NO (1) NO801443L (es)
RO (1) RO79525B (es)
YU (1) YU41923B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6146873A (en) * 1994-11-10 2000-11-14 Baxter Aktiengesellschaft Production of orthomyxoviruses in monkey kidney cells using protein-free media
US5698433A (en) * 1994-11-10 1997-12-16 Immuno Ag Method for producing influenza virus and vaccine
US5753489A (en) * 1994-11-10 1998-05-19 Immuno Ag Method for producing viruses and vaccines in serum-free culture
ATE542891T1 (de) * 1994-11-10 2012-02-15 Baxter Healthcare Sa Verfahren zur herstellung von biologischen produkten in protein-freier kultur
JPH11509081A (ja) * 1994-11-16 1999-08-17 セント ジュード チルドレンズ リサーチ ホスピタル 新規の複製プロセス
DE19612967A1 (de) * 1996-04-01 1997-10-02 Behringwerke Ag Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren
DE19612966B4 (de) 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren
DE10144906B4 (de) * 2001-09-12 2013-11-28 Novartis Vaccines And Diagnostics Gmbh Verfahren zur großtechnischen Herstellung von Impfstoffen
US6830917B2 (en) 2001-12-10 2004-12-14 Baxter Healthcare S.A. Method of isolation and purification of trypsin from pronase protease and use thereof
CA2586690A1 (en) 2004-11-03 2006-06-15 Novartis Vaccines And Diagnostics, Inc. Influenza vaccination
EP2022849A4 (en) 2006-05-11 2010-10-06 Chemo Sero Therapeut Res Inst METHOD FOR PROLIFERATION OF INFLUENZA VIRUS
US8506966B2 (en) 2008-02-22 2013-08-13 Novartis Ag Adjuvanted influenza vaccines for pediatric use
TW201012930A (en) * 2008-06-16 2010-04-01 Intervet Int Bv Method of replicating viruses in suspension
AU2010212550B2 (en) 2009-02-10 2016-03-10 Seqirus UK Limited Influenza vaccines with reduced amounts of squalene

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2262962B1 (es) * 1974-03-05 1977-11-04 Science Union & Cie

Also Published As

Publication number Publication date
ES491517A0 (es) 1981-04-01
EP0019218B1 (de) 1985-11-13
RO79525A (ro) 1984-07-17
NO801443L (no) 1980-11-17
EP0019218A3 (en) 1981-03-25
DE3071225D1 (en) 1985-12-19
YU41923B (en) 1988-02-29
CA1122527A (en) 1982-04-27
EP0019218A2 (de) 1980-11-26
JPH0124769B2 (es) 1989-05-15
EP0019218B2 (de) 1995-03-01
IL60063A0 (en) 1980-07-31
ATE16454T1 (de) 1985-11-15
AR220838A1 (es) 1980-11-28
JPS55153723A (en) 1980-11-29
YU126580A (en) 1983-12-31
AU535804B2 (en) 1984-04-05
AU5824480A (en) 1980-11-20
DK154749B (da) 1988-12-19
RO79525B (ro) 1984-09-30
DK212580A (da) 1980-11-16
DK154749C (da) 1989-05-16

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