ES8101051A1 - Procedimiento mejorado para la preparacion de sulfonilureas - Google Patents
Procedimiento mejorado para la preparacion de sulfonilureasInfo
- Publication number
- ES8101051A1 ES8101051A1 ES490202A ES490202A ES8101051A1 ES 8101051 A1 ES8101051 A1 ES 8101051A1 ES 490202 A ES490202 A ES 490202A ES 490202 A ES490202 A ES 490202A ES 8101051 A1 ES8101051 A1 ES 8101051A1
- Authority
- ES
- Spain
- Prior art keywords
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- sulfonyl ureas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE SULFONILUREAS. CONSISTE EN HACER REACCIONAR HALOGENUROS DE BENCENOSULFONILO, SUSTITUIDOS CON UREAS SUSTITUIDAS O ACIDOS SULFINICOS SUSTITUIDOS EN PRESENCIA DE AGENTES DE CONDENSACION ACIDOS O SUS SALES DE METALES ALCANLINOS CON R-R1-N-HIDROXI-UREA. *FORMULA* SE OBTIENEN PRODUCTOS DE FORMULA GENERAL (I). LOS PRODUCTOS OBTENIDOS PUEDEN SER TRATADOS CON AGENTES ALCALINOS PARA LA FORMACION DE SALES. DISMINUCION INTENSA Y DE LARGA DURACION DEL NIVEL DE AZUCAR EN LA SANGRE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782828079 DE2828079A1 (de) | 1978-06-27 | 1978-06-27 | Sulfonylharnstoffe und verfahren zu ihrer herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8101051A1 true ES8101051A1 (es) | 1980-12-01 |
ES490202A0 ES490202A0 (es) | 1980-12-01 |
Family
ID=6042843
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481755A Expired ES481755A1 (es) | 1978-06-27 | 1979-06-21 | Procedimiento mejorado para la preparacion de sulfonilureas. |
ES490202A Granted ES490202A0 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
ES490201A Granted ES490201A0 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
ES490199A Granted ES490199A0 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
ES490198A Granted ES490198A0 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
ES490200A Expired ES8101050A1 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481755A Expired ES481755A1 (es) | 1978-06-27 | 1979-06-21 | Procedimiento mejorado para la preparacion de sulfonilureas. |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES490201A Granted ES490201A0 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
ES490199A Granted ES490199A0 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
ES490198A Granted ES490198A0 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
ES490200A Expired ES8101050A1 (es) | 1978-06-27 | 1980-04-01 | Procedimiento mejorado para la preparacion de sulfonilureas |
Country Status (31)
Country | Link |
---|---|
US (1) | US4282239A (es) |
EP (1) | EP0006587B1 (es) |
JP (1) | JPS5511580A (es) |
AR (1) | AR223975A1 (es) |
AT (1) | ATE382T1 (es) |
AU (1) | AU527494B2 (es) |
BE (1) | BE877308A (es) |
CA (1) | CA1122598A (es) |
CU (1) | CU35107A (es) |
DD (1) | DD144539A5 (es) |
DE (2) | DE2828079A1 (es) |
DK (1) | DK269579A (es) |
ES (6) | ES481755A1 (es) |
FI (1) | FI792008A (es) |
FR (1) | FR2429786A1 (es) |
GB (1) | GB2024221A (es) |
GR (1) | GR74059B (es) |
IL (1) | IL57639A0 (es) |
IT (1) | IT1121923B (es) |
JO (1) | JO1010B1 (es) |
LU (1) | LU81423A1 (es) |
MA (1) | MA18501A1 (es) |
MT (1) | MTP848B (es) |
MW (1) | MW2079A1 (es) |
NL (1) | NL7904975A (es) |
NO (1) | NO792148L (es) |
OA (1) | OA06283A (es) |
PT (1) | PT69803A (es) |
SE (1) | SE7905557L (es) |
ZA (1) | ZA793178B (es) |
ZM (1) | ZM5879A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2951135A1 (de) * | 1979-12-19 | 1981-06-25 | Hoechst Ag, 6230 Frankfurt | Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
DE3134780A1 (de) * | 1981-09-02 | 1983-03-10 | Hoechst Ag, 6000 Frankfurt | "sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung" |
CN103058913B (zh) * | 2012-12-13 | 2015-09-30 | 江苏弘和药物研发有限公司 | 5-氯异吲哚酮的合成方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1618389U (de) | 1950-10-05 | 1950-12-28 | Eisen Fuchs G M B H | Endpreistabelle fuer walzeisen. |
DE1670700U (de) | 1952-11-12 | 1954-01-21 | Siemens Ag | Aufhaengevorrichtung fuer pendelleuchten. |
DE1670660U (de) | 1953-08-26 | 1954-01-21 | Aerzener Bastkunst M Cramer | Halter fuer blumentoepfe und pflanzenschalen. |
LU47776A1 (es) * | 1964-07-30 | 1966-07-13 | ||
DE1445774A1 (de) * | 1964-07-30 | 1969-01-23 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
FR1528139A (fr) * | 1966-05-14 | 1968-06-07 | Hoechst Ag | Benzène-sulfonyl-urées et leur préparation |
DE1670700B2 (de) * | 1966-05-14 | 1978-06-22 | Hoechst Ag, 6000 Frankfurt | Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung |
US3705151A (en) * | 1967-08-12 | 1972-12-05 | Hoechst Ag | Benzene-sulfonyl semicarbazides and process for preparing them |
DE2000339C3 (de) * | 1970-01-05 | 1979-04-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Isochinolinderivate |
US3819633A (en) * | 1970-04-01 | 1974-06-25 | Erba Carlo Spa | (iso)quinolyl sulfonylureas having antidiabetic activity |
GB1329812A (en) * | 1971-02-15 | 1973-09-12 | Science Union & Cie | Benzenesulphonyl semicarbazides and a process for their preparation |
BE791638A (fr) * | 1971-11-20 | 1973-05-21 | Hoechst Ag | Sulfonyl-urees, leur procede de preparation et leurs applications |
DE2238870C3 (de) | 1972-08-07 | 1978-09-28 | Hoechst Ag, 6000 Frankfurt | Benzolsulfonylharnstoffe |
IL45823A (en) * | 1973-10-20 | 1977-10-31 | Hoechst Ag | Substituted 1-phenyl-4-alkyl(dialkyl or cyclic) aminoalkyl-1,4-dihydro-2h-isoquinoline-3-one derivatives |
NL179275C (nl) * | 1973-10-24 | 1986-08-18 | Otsuka Pharma Co Ltd | Werkwijze voor de bereiding van farmacologisch werkzame glycerol-derivaten en werkwijze voor de bereiding van preparaten die ze bevatten. |
US4129729A (en) * | 1978-01-03 | 1978-12-12 | Monsanto Company | 3-Phenacyl and phenacylidene phthalimidines and corresponding naphthoyl derivatives |
-
1974
- 1974-06-25 MT MT848A patent/MTP848B/xx unknown
-
1978
- 1978-06-27 DE DE19782828079 patent/DE2828079A1/de not_active Withdrawn
-
1979
- 1979-04-22 PT PT69803A patent/PT69803A/pt unknown
- 1979-05-07 FR FR7911479A patent/FR2429786A1/fr active Granted
- 1979-06-21 CU CU7935107A patent/CU35107A/es unknown
- 1979-06-21 ES ES481755A patent/ES481755A1/es not_active Expired
- 1979-06-22 DE DE7979102066T patent/DE2961309D1/de not_active Expired
- 1979-06-22 EP EP79102066A patent/EP0006587B1/de not_active Expired
- 1979-06-22 AT AT79102066T patent/ATE382T1/de active
- 1979-06-25 US US06/051,548 patent/US4282239A/en not_active Expired - Lifetime
- 1979-06-25 LU LU81423A patent/LU81423A1/de unknown
- 1979-06-25 FI FI792008A patent/FI792008A/fi not_active Application Discontinuation
- 1979-06-25 IL IL57639A patent/IL57639A0/xx unknown
- 1979-06-25 ZM ZM58/79A patent/ZM5879A1/xx unknown
- 1979-06-25 AR AR277039A patent/AR223975A1/es active
- 1979-06-25 JO JO19791010A patent/JO1010B1/en active
- 1979-06-25 MW MW20/79A patent/MW2079A1/xx unknown
- 1979-06-25 GR GR59423A patent/GR74059B/el unknown
- 1979-06-25 GB GB7922038A patent/GB2024221A/en not_active Withdrawn
- 1979-06-25 SE SE7905557A patent/SE7905557L/xx unknown
- 1979-06-25 DD DD79213876A patent/DD144539A5/de unknown
- 1979-06-25 IT IT23846/79A patent/IT1121923B/it active
- 1979-06-26 CA CA330,942A patent/CA1122598A/en not_active Expired
- 1979-06-26 MA MA18696A patent/MA18501A1/fr unknown
- 1979-06-26 DK DK269579A patent/DK269579A/da not_active Application Discontinuation
- 1979-06-26 AU AU48380/79A patent/AU527494B2/en not_active Expired - Fee Related
- 1979-06-26 NO NO792148A patent/NO792148L/no unknown
- 1979-06-26 ZA ZA793178A patent/ZA793178B/xx unknown
- 1979-06-26 NL NL7904975A patent/NL7904975A/nl not_active Application Discontinuation
- 1979-06-26 OA OA56836A patent/OA06283A/xx unknown
- 1979-06-27 JP JP8027979A patent/JPS5511580A/ja active Pending
- 1979-06-27 BE BE0/195996A patent/BE877308A/xx unknown
-
1980
- 1980-04-01 ES ES490202A patent/ES490202A0/es active Granted
- 1980-04-01 ES ES490201A patent/ES490201A0/es active Granted
- 1980-04-01 ES ES490199A patent/ES490199A0/es active Granted
- 1980-04-01 ES ES490198A patent/ES490198A0/es active Granted
- 1980-04-01 ES ES490200A patent/ES8101050A1/es not_active Expired
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