ES8308550A1 - Procedimiento para la preparacion de derivados de tiazolina. - Google Patents

Procedimiento para la preparacion de derivados de tiazolina.

Info

Publication number
ES8308550A1
ES8308550A1 ES518273A ES518273A ES8308550A1 ES 8308550 A1 ES8308550 A1 ES 8308550A1 ES 518273 A ES518273 A ES 518273A ES 518273 A ES518273 A ES 518273A ES 8308550 A1 ES8308550 A1 ES 8308550A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical preparations
preparations containing
thiazoline derivatives
thiazoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518273A
Other languages
English (en)
Other versions
ES518273A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES518273A0 publication Critical patent/ES518273A0/es
Publication of ES8308550A1 publication Critical patent/ES8308550A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE TIAZOLINA. CONSISTE EN SOMETER A COMPUESTOS (II) A SOLVOLISIS A TEMPERATURAS DE 20 A 100 C, CON UNA SOLUCION DE HIDROGENO INORGANICO, CON AMONIACO O CON UNA SOLUCION DE UNA AMINA ORGANICA PRIMARIA O SECUNDARIA. PREFERENTEMENTE SE TRABAJA, EXPULSANDO EL DISOLVENTE EN VACIO BAJO PRESION REDUCIDA, AJUSTANDO EL PH A 4-6 CON UN ACIDO TAL COMO EL ACETICO O EL CLORHIDRICO EN CALIENTE A 40-80 C Y SEPARANDO EL PRECIPITADO POR FILTRACION. LOS COMPUESTOS OBTENIDOS TIENEN LA FORMULA GENERAL (I).
ES518273A 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina. Expired ES8308550A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803049460 DE3049460A1 (de) 1980-12-30 1980-12-30 "thiazolinderivate, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen

Publications (2)

Publication Number Publication Date
ES518273A0 ES518273A0 (es) 1983-09-01
ES8308550A1 true ES8308550A1 (es) 1983-09-01

Family

ID=6120529

Family Applications (5)

Application Number Title Priority Date Filing Date
ES508293A Granted ES508293A0 (es) 1980-12-30 1981-12-23 "procedimiento para la preparacion de derivados de tiazolina".
ES518272A Expired ES8308549A1 (es) 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina.
ES518273A Expired ES8308550A1 (es) 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina.
ES518274A Granted ES518274A0 (es) 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina.
ES518271A Expired ES8402829A1 (es) 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES508293A Granted ES508293A0 (es) 1980-12-30 1981-12-23 "procedimiento para la preparacion de derivados de tiazolina".
ES518272A Expired ES8308549A1 (es) 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES518274A Granted ES518274A0 (es) 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina.
ES518271A Expired ES8402829A1 (es) 1980-12-30 1982-12-16 Procedimiento para la preparacion de derivados de tiazolina.

Country Status (17)

Country Link
US (1) US4421757A (es)
EP (1) EP0055458B1 (es)
JP (1) JPS57134472A (es)
KR (1) KR830007601A (es)
AR (2) AR231134A1 (es)
AT (1) ATE11778T1 (es)
AU (1) AU542670B2 (es)
CA (1) CA1173836A (es)
DE (2) DE3049460A1 (es)
DK (1) DK581181A (es)
ES (5) ES508293A0 (es)
FI (1) FI814175L (es)
HU (1) HU184976B (es)
IE (1) IE52259B1 (es)
IL (1) IL64653A (es)
NO (1) NO154551B (es)
ZA (1) ZA818968B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761422A (en) * 1986-11-20 1988-08-02 Lusofarmaco Istituto Lusofarmaco D'italia Spa (2-amino-4-aryl-thiazole-5-yl)ethanols and their derivatives having diuretic activity and methods for preparing the same
US6353006B1 (en) 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
EP1144396A2 (en) * 1999-01-14 2001-10-17 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
FR2796643B1 (fr) * 1999-07-22 2005-04-29 Sod Conseils Rech Applic Derives de 2-arylimino-2, 3-dihydrothiazoles, leurs procedes de preparation et leur utilisation therapeutique
FR2819508B1 (fr) * 2001-01-12 2005-01-21 Sod Conseils Rech Applic Derives de 2-arylimino-2, 3-dihydorthiazoles, leurs procedes de preparation et leur utilisation therapeutiques
KR100509401B1 (ko) 1999-09-14 2005-08-22 시오노기세이야쿠가부시키가이샤 2-이미노-1,3-티아진 유도체
US7271195B2 (en) 2003-06-10 2007-09-18 Kalypsys, Inc. Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease
BRPI0411275A (pt) * 2003-06-10 2006-08-01 Kalypsys Inc compostos de carbonila como inibidores de histona deacetilase para tratamento de doenças; composição farmacêutica; método de modular a atividade catalìtica de hdac; método de tratar doença em um indivìduo; utilização de um composto ou composição; método de inibir hdac

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2436263C2 (de) * 1974-07-27 1983-02-17 Hoechst Ag, 6000 Frankfurt Thiazolidinderivate und Verfahren zu ihrer Herstellung
DE2533821A1 (de) * 1975-07-29 1977-02-17 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
DE2546165A1 (de) * 1975-10-15 1977-04-28 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
SE7700436L (sv) * 1976-01-17 1977-07-18 Hoechst Ag Tiazolidinderivat och forfarande for deras framstellning
DE2926771A1 (de) * 1979-07-03 1981-01-15 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ES8305342A1 (es) 1983-04-01
ES518272A0 (es) 1983-09-01
FI814175L (fi) 1982-07-01
IL64653A (en) 1985-09-29
ATE11778T1 (de) 1985-02-15
AU7906881A (en) 1982-07-08
AR231978A1 (es) 1985-04-30
ES518271A0 (es) 1984-02-16
KR830007601A (ko) 1983-11-04
ES8402829A1 (es) 1984-02-16
DE3049460A1 (de) 1982-07-29
CA1173836A (en) 1984-09-04
ES8308551A1 (es) 1983-09-01
JPS57134472A (en) 1982-08-19
NO814468L (no) 1982-07-01
NO154551B (no) 1986-07-07
IL64653A0 (en) 1982-03-31
ES8308549A1 (es) 1983-09-01
ES518273A0 (es) 1983-09-01
EP0055458A3 (en) 1982-10-20
DK581181A (da) 1982-07-01
US4421757A (en) 1983-12-20
IE52259B1 (en) 1987-08-19
HU184976B (en) 1984-11-28
DE3168978D1 (en) 1985-03-28
ES518274A0 (es) 1983-09-01
ZA818968B (en) 1982-11-24
IE813057L (en) 1982-06-30
EP0055458A2 (de) 1982-07-07
EP0055458B1 (de) 1985-02-13
ES508293A0 (es) 1983-04-01
AR231134A1 (es) 1984-09-28
AU542670B2 (en) 1985-02-28

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