ES552525A0 - Un metodo para preparar derivados de cefem - Google Patents
Un metodo para preparar derivados de cefemInfo
- Publication number
- ES552525A0 ES552525A0 ES552525A ES552525A ES552525A0 ES 552525 A0 ES552525 A0 ES 552525A0 ES 552525 A ES552525 A ES 552525A ES 552525 A ES552525 A ES 552525A ES 552525 A0 ES552525 A0 ES 552525A0
- Authority
- ES
- Spain
- Prior art keywords
- cefem derivatives
- preparing
- preparing cefem
- derivatives
- cefem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP1985/000102 WO1986005184A1 (en) | 1985-03-01 | 1985-03-01 | Antibacterial compound |
| NO851538A NO165842C (no) | 1984-04-23 | 1985-04-17 | Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser. |
| JP20932085 | 1985-09-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8705892A1 ES8705892A1 (es) | 1987-05-16 |
| ES552525A0 true ES552525A0 (es) | 1987-05-16 |
Family
ID=27304712
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES552525A Expired ES8705892A1 (es) | 1985-03-01 | 1986-02-28 | Un metodo para preparar derivados de cefem |
| ES557183A Expired ES8801290A1 (es) | 1985-03-01 | 1986-11-03 | Un metodo para preparar derivados de cefem |
| ES557182A Expired ES8801289A1 (es) | 1985-03-01 | 1986-11-03 | Un metodo para preparar derivados de cefem |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES557183A Expired ES8801290A1 (es) | 1985-03-01 | 1986-11-03 | Un metodo para preparar derivados de cefem |
| ES557182A Expired ES8801289A1 (es) | 1985-03-01 | 1986-11-03 | Un metodo para preparar derivados de cefem |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0203271B1 (es) |
| JP (1) | JPS62149682A (es) |
| CN (1) | CN1030657C (es) |
| AR (1) | AR247398A1 (es) |
| AU (1) | AU598728B2 (es) |
| CA (1) | CA1295995C (es) |
| DE (1) | DE3688477T2 (es) |
| ES (3) | ES8705892A1 (es) |
| NO (1) | NO166283C (es) |
| NZ (1) | NZ215333A (es) |
| WO (1) | WO1986005183A1 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2519054B2 (ja) * | 1986-06-09 | 1996-07-31 | 武田薬品工業株式会社 | 新規セフェム化合物 |
| US4921851A (en) * | 1986-06-09 | 1990-05-01 | Takeda Chemical Industries, Ltd. | Cephem compounds, their production and use |
| DE3707019A1 (de) * | 1987-03-05 | 1988-09-15 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
| EP0304858A3 (en) * | 1987-08-25 | 1989-12-20 | Takeda Chemical Industries, Ltd. | Cephem compounds, their production and use |
| US4933334A (en) * | 1987-12-04 | 1990-06-12 | Takeda Chemical Industries, Ltd. | Antibiotic composition |
| AU615966B2 (en) * | 1987-12-04 | 1991-10-17 | Takeda Chemical Industries Ltd. | Crystals of cephem hydrochloride |
| PH27291A (en) * | 1989-01-31 | 1993-05-04 | Takeda Chemical Industries Ltd | Imidazolpyrimidazines their production and use |
| EP0440119A1 (en) * | 1990-01-31 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Imidazopyridazine compounds, their production and use |
| DE69106902T2 (de) * | 1990-03-01 | 1995-07-06 | Takeda Chemical Industries Ltd | Imidazopyridazine, ihre Herstellung und Verwendung. |
| JPH09110877A (ja) * | 1995-10-17 | 1997-04-28 | Katayama Seiyakushiyo:Kk | セフェム化合物、その製造法及びそれを含有する抗菌剤 |
| TW526202B (en) | 1998-11-27 | 2003-04-01 | Shionogi & Amp Co | Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity |
| BRPI0921701B8 (pt) | 2008-10-31 | 2022-06-07 | Shionogi & Co | Cefarosporina tendo um grupo catecol, seu uso e composição farmacêutica que a compreende |
| CN101735245A (zh) * | 2008-11-05 | 2010-06-16 | 杨石 | 盐酸头孢唑兰及其中间体的制备方法 |
| CN102070655B (zh) * | 2009-11-23 | 2012-09-26 | 山东轩竹医药科技有限公司 | 含有咪唑环的头孢菌素衍生物 |
| KR20130018845A (ko) | 2010-04-05 | 2013-02-25 | 시오노기세야쿠 가부시키가이샤 | 카테콜기를 갖는 세펨 화합물 |
| WO2011125966A1 (ja) | 2010-04-05 | 2011-10-13 | 塩野義製薬株式会社 | 擬似カテコール基を有するセフェム化合物 |
| TWI547496B (zh) | 2011-10-04 | 2016-09-01 | 葛蘭素集團公司 | 抗菌化合物 |
| CN103570749A (zh) * | 2013-11-15 | 2014-02-12 | 安徽悦康凯悦制药有限公司 | 一种头孢唑兰制备工艺 |
| CN105153201B (zh) * | 2015-08-29 | 2017-08-22 | 济南康和医药科技有限公司 | 一种盐酸头孢唑兰的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165430A (en) * | 1976-03-19 | 1979-08-21 | Glaxo Laboratories Limited | Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group |
| ES8306160A1 (es) * | 1981-04-03 | 1983-05-01 | Fujisawa Pharmaceutical Co | "procedimiento para preparar un nuevo compuesto de cefem". |
| DE3247614A1 (de) * | 1982-12-23 | 1984-07-05 | Hoechst Ag, 6230 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
| DE3336757A1 (de) * | 1983-10-08 | 1985-04-25 | Hoechst Ag, 6230 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
| NO165842C (no) * | 1984-04-23 | 1991-04-17 | Takeda Chemical Industries Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser. |
| PH22107A (en) * | 1984-06-07 | 1988-06-01 | Takeda Chemical Industries Ltd | 3-pyrazolo(1,5-a)pyrdinium cephem compounds |
-
1986
- 1986-02-27 NO NO860725A patent/NO166283C/no unknown
- 1986-02-27 EP EP86102584A patent/EP0203271B1/en not_active Expired - Lifetime
- 1986-02-27 DE DE8686102584T patent/DE3688477T2/de not_active Expired - Fee Related
- 1986-02-28 AU AU54168/86A patent/AU598728B2/en not_active Ceased
- 1986-02-28 WO PCT/JP1986/000099 patent/WO1986005183A1/en unknown
- 1986-02-28 JP JP61044991A patent/JPS62149682A/ja active Granted
- 1986-02-28 CN CN86102034A patent/CN1030657C/zh not_active Expired - Fee Related
- 1986-02-28 NZ NZ215333A patent/NZ215333A/xx unknown
- 1986-02-28 CA CA000502935A patent/CA1295995C/en not_active Expired - Lifetime
- 1986-02-28 ES ES552525A patent/ES8705892A1/es not_active Expired
- 1986-11-03 ES ES557183A patent/ES8801290A1/es not_active Expired
- 1986-11-03 ES ES557182A patent/ES8801289A1/es not_active Expired
-
1990
- 1990-02-07 AR AR90316105A patent/AR247398A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0203271A2 (en) | 1986-12-03 |
| AR247398A1 (es) | 1994-12-29 |
| AU598728B2 (en) | 1990-07-05 |
| AU5416886A (en) | 1986-09-04 |
| EP0203271B1 (en) | 1993-05-26 |
| EP0203271A3 (en) | 1988-06-01 |
| JPH0257074B2 (es) | 1990-12-03 |
| WO1986005183A1 (en) | 1986-09-12 |
| NO860725L (no) | 1986-09-02 |
| ES557183A0 (es) | 1988-01-01 |
| CN1030657C (zh) | 1996-01-10 |
| DE3688477T2 (de) | 1993-09-16 |
| ES8705892A1 (es) | 1987-05-16 |
| ES8801289A1 (es) | 1988-01-01 |
| NZ215333A (en) | 1988-09-29 |
| NO166283C (no) | 1991-06-26 |
| ES557182A0 (es) | 1988-01-01 |
| DE3688477D1 (de) | 1993-07-01 |
| ES8801290A1 (es) | 1988-01-01 |
| CA1295995C (en) | 1992-02-18 |
| CN86102034A (zh) | 1987-01-07 |
| NO166283B (no) | 1991-03-18 |
| JPS62149682A (ja) | 1987-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990201 |