ES541620A0 - Un procedimiento para la preparacion de aciltripeptidos in- munoestimulantes - Google Patents

Un procedimiento para la preparacion de aciltripeptidos in- munoestimulantes

Info

Publication number
ES541620A0
ES541620A0 ES541620A ES541620A ES541620A0 ES 541620 A0 ES541620 A0 ES 541620A0 ES 541620 A ES541620 A ES 541620A ES 541620 A ES541620 A ES 541620A ES 541620 A0 ES541620 A0 ES 541620A0
Authority
ES
Spain
Prior art keywords
acil
immunostimulant
tripeptides
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES541620A
Other languages
English (en)
Other versions
ES8605821A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES541620A0 publication Critical patent/ES541620A0/es
Publication of ES8605821A1 publication Critical patent/ES8605821A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/16—Eight-membered rings
    • C07D313/18—Eight-membered rings not condensed with other rings
ES541620A 1984-03-30 1985-03-27 Un procedimiento para la preparacion de aciltripeptidos in- munoestimulantes Expired ES8605821A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/595,169 US4565653A (en) 1984-03-30 1984-03-30 Acyltripeptide immunostimulants

Publications (2)

Publication Number Publication Date
ES541620A0 true ES541620A0 (es) 1986-04-01
ES8605821A1 ES8605821A1 (es) 1986-04-01

Family

ID=24382038

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541620A Expired ES8605821A1 (es) 1984-03-30 1985-03-27 Un procedimiento para la preparacion de aciltripeptidos in- munoestimulantes

Country Status (20)

Country Link
US (1) US4565653A (es)
EP (1) EP0157572A3 (es)
JP (1) JPS60224699A (es)
KR (1) KR870000372B1 (es)
AU (2) AU552919B2 (es)
CA (1) CA1270098A (es)
DD (1) DD239406A5 (es)
DK (1) DK142485A (es)
EG (1) EG17928A (es)
ES (1) ES8605821A1 (es)
FI (1) FI851271L (es)
GR (1) GR850783B (es)
HU (1) HU198086B (es)
IL (1) IL74758A (es)
NO (1) NO851278L (es)
NZ (1) NZ211634A (es)
PH (1) PH21303A (es)
PL (1) PL252659A1 (es)
PT (1) PT80181B (es)
ZA (1) ZA852335B (es)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1295784C (en) * 1985-11-25 1992-02-11 James Patrick Rizzi Peptide immunostimulants
JPH0718039B2 (ja) * 1986-03-26 1995-03-01 株式会社豊田自動織機製作所 粉末付加亜鉛めっき鋼板の製造方法
WO1988001612A1 (en) * 1986-08-27 1988-03-10 Pfizer Inc. Processes and intermediates for n-(s-3-alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-d-alanine
WO1988001613A1 (en) * 1986-08-27 1988-03-10 Pfizer Inc. Crystalline n-(s-3-methylheptanoyl)-d-gamma-glutamyl-glycyl-d-alanine, and processes and intermediates therefor
DE3700173A1 (de) * 1987-01-05 1988-07-14 Hoechst Ag Verfahren zur herstellung von lipophilen aminosaeurederivaten sowie lipophile aminosaeurederivate
DE3820528A1 (de) * 1988-06-16 1989-12-21 Bayer Ag Mittel zur insekten- und milbenabwehr
US5245079A (en) * 1989-02-21 1993-09-14 Pfizer Inc. Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine
US5185464A (en) * 1989-02-21 1993-02-09 Pfizer Inc. Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor
US5248820A (en) * 1989-02-21 1993-09-28 Pfizer Inc. Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor
US5136020A (en) * 1989-02-21 1992-08-04 Pfizer Inc. Crystalline n-(s-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor
US5134225A (en) * 1989-02-21 1992-07-28 Pfizer Inc. Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-D-alanine
EP0617009B1 (en) 1992-10-15 1999-09-08 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Novel amino acid derivative
US5798387A (en) * 1992-10-15 1998-08-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Amino acid derivatives
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US7795210B2 (en) * 2001-10-10 2010-09-14 Novo Nordisk A/S Protein remodeling methods and proteins/peptides produced by the methods
US7399613B2 (en) * 2001-10-10 2008-07-15 Neose Technologies, Inc. Sialic acid nucleotide sugars
US7696163B2 (en) 2001-10-10 2010-04-13 Novo Nordisk A/S Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7157277B2 (en) * 2001-11-28 2007-01-02 Neose Technologies, Inc. Factor VIII remodeling and glycoconjugation of Factor VIII
US8008252B2 (en) * 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
US7173003B2 (en) * 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
MXPA04012496A (es) * 2002-06-21 2005-09-12 Novo Nordisk Healthcare Ag Glicoformos del factor vii pegilados.
CA2519092C (en) * 2003-03-14 2014-08-05 Neose Technologies, Inc. Branched water-soluble polymers and their conjugates
WO2007022512A2 (en) * 2005-08-19 2007-02-22 Neose Technologies, Inc. Glycopegylated factor vii and factor viia
US8791070B2 (en) 2003-04-09 2014-07-29 Novo Nordisk A/S Glycopegylated factor IX
US7691603B2 (en) * 2003-04-09 2010-04-06 Novo Nordisk A/S Intracellular formation of peptide conjugates
PL1615945T3 (pl) 2003-04-09 2012-03-30 Ratiopharm Gmbh Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami
BRPI0410164A (pt) 2003-05-09 2006-05-16 Neose Technologies Inc composições e métodos para preparação de mutantes de glicosilação de hormÈnio do crescimento humano
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US8633157B2 (en) * 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
KR20060120141A (ko) * 2003-11-24 2006-11-24 네오스 테크놀로지스, 인크. 글리코페질화 에리트로포이에틴
US20080305992A1 (en) * 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20060040856A1 (en) * 2003-12-03 2006-02-23 Neose Technologies, Inc. Glycopegylated factor IX
US7956032B2 (en) * 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
BRPI0417342A (pt) * 2003-12-03 2007-04-17 Neose Technologies Inc fator estimulante de colÈnia de granulócitos glicopeguilado
US20080318850A1 (en) * 2003-12-03 2008-12-25 Neose Technologies, Inc. Glycopegylated Factor Ix
KR101439880B1 (ko) * 2004-01-08 2014-09-12 라티오팜 게엠베하 펩티드의 오-결합형 글리코실화
EP1771066A2 (en) 2004-07-13 2007-04-11 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 glp-1
EP1799249A2 (en) * 2004-09-10 2007-06-27 Neose Technologies, Inc. Glycopegylated interferon alpha
WO2006050247A2 (en) * 2004-10-29 2006-05-11 Neose Technologies, Inc. Remodeling and glycopegylation of fibroblast growth factor (fgf)
EP1838332A1 (en) * 2005-01-06 2007-10-03 Neose Technologies, Inc. Glycoconjugation using saccharyl fragments
NZ556436A (en) * 2005-01-10 2010-11-26 Biogenerix Ag Glycopegylated granulocyte colony stimulating factor
WO2006105426A2 (en) * 2005-03-30 2006-10-05 Neose Technologies, Inc. Manufacturing process for the production of peptides grown in insect cell lines
EP2386571B1 (en) * 2005-04-08 2016-06-01 ratiopharm GmbH Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
WO2006127910A2 (en) * 2005-05-25 2006-11-30 Neose Technologies, Inc. Glycopegylated erythropoietin formulations
JP5216580B2 (ja) * 2005-05-25 2013-06-19 ノヴォ ノルディスク アー／エス グリコペグ化第ｉｘ因子
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) * 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
ES2516694T3 (es) * 2006-07-21 2014-10-31 Ratiopharm Gmbh Glicosilación de péptidos a través de secuencias de glicosilación con unión en O
WO2008057683A2 (en) * 2006-10-03 2008-05-15 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
LT2068907T (lt) * 2006-10-04 2018-01-10 Novo Nordisk A/S Glicerolio sujungti pegilinti sacharidai ir glikopeptidai
WO2008073620A2 (en) * 2006-11-02 2008-06-19 Neose Technologies, Inc. Manufacturing process for the production of polypeptides expressed in insect cell-lines
BRPI0809670A8 (pt) * 2007-04-03 2018-12-18 Biogenerix Ag métodos para aumentar a produção de célula tronco, para aumentar o número de granulócitos em um indivíduo, para prevenir, tratar e aliviar a mielossupressão que resulta de uma terapia contra o câncer, para tratar uma condição em um indivíduo, para tratar neutropenia e trombocitopenia em um mamífero, para expandir células tronco hematopoiéticas em cultura, para aumentar a hematopoiese em um indivíduo, para aumentar o número de célulars progenitoras hematopoiéticas em um indivíduo, e para fornecer enxerto estável da medula óssea, e, forma de dosagem oral.
US20090053167A1 (en) * 2007-05-14 2009-02-26 Neose Technologies, Inc. C-, S- and N-glycosylation of peptides
US20110177029A1 (en) * 2007-06-04 2011-07-21 Novo Nordisk A/S O-linked glycosylation using n-acetylglucosaminyl transferases
CN101778859B (zh) * 2007-06-12 2014-03-26 诺和诺德公司 改良的用于生产核苷酸糖的方法
US8207112B2 (en) * 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
US20100286067A1 (en) * 2008-01-08 2010-11-11 Biogenerix Ag Glycoconjugation of polypeptides using oligosaccharyltransferases
CN103497246B (zh) 2008-02-27 2016-08-10 诺沃—诺迪斯克有限公司 缀合的因子viii分子

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322341A (en) * 1980-05-13 1982-03-30 Fujisawa Pharmaceutical Co Peptide, process for preparation thereof and use thereof
DK156252C (da) * 1979-07-31 1989-12-18 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af di-, tri- eller tetrapeptidderivater eller salte deraf
DE3070278D1 (en) * 1979-10-11 1985-04-18 Fujisawa Pharmaceutical Co Peptides, processes for their preparation and pharmaceutical compositions containing them
GR81332B (es) * 1980-12-01 1984-12-11 Fujisawa Pharmaceutical Co
US4493794A (en) * 1980-12-31 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Peptide, process for preparation thereof and use thereof

Also Published As

Publication number Publication date
HUT37443A (en) 1985-12-28
PT80181A (en) 1985-04-01
KR850006939A (ko) 1985-10-25
IL74758A0 (en) 1985-06-30
AU5647686A (en) 1986-09-04
NO851278L (no) 1985-10-01
EP0157572A3 (en) 1987-01-07
HU198086B (en) 1989-07-28
AU566460B2 (en) 1987-10-22
ZA852335B (en) 1986-11-26
US4565653A (en) 1986-01-21
DK142485D0 (da) 1985-03-29
JPS60224699A (ja) 1985-11-09
AU552919B2 (en) 1986-06-26
DK142485A (da) 1985-10-01
PT80181B (en) 1987-03-20
NZ211634A (en) 1988-10-28
PL252659A1 (en) 1985-11-19
KR870000372B1 (ko) 1987-03-06
FI851271L (fi) 1985-10-01
DD239406A5 (de) 1986-09-24
PH21303A (en) 1987-09-28
CA1270098A (en) 1990-06-05
FI851271A0 (fi) 1985-03-29
EG17928A (en) 1991-08-30
ES8605821A1 (es) 1986-04-01
GR850783B (es) 1985-11-25
EP0157572A2 (en) 1985-10-09
IL74758A (en) 1988-06-30
AU4052385A (en) 1985-10-03

Similar Documents

Publication Publication Date Title
ES541620A0 (es) Un procedimiento para la preparacion de aciltripeptidos in- munoestimulantes
ES547840A0 (es) Un procedimiento para la preparacion de alquilsulfonamidofe-nilalquilaminas
ES551249A0 (es) Un procedimiento para la preparacion de peptidilaminodioles.
ES557743A0 (es) Un procedimiento para la preparacion de nuevas piranopiridinas
ES546800A0 (es) Un procedimiento para la preparacion de surfactantes de fos-fato
ES540366A0 (es) Un procedimiento para la preparacion de un compuesto
ES556738A0 (es) Un procedimiento para la preparacion de nuevos piridazinaminas.
ES554983A0 (es) Un procedimiento para la preparacion de silileteres.
ES557126A0 (es) Un procedimiento para la preparacion de triazolobenzodiazepinas
ES557413A0 (es) Un procedimiento para la preparacion de un polialquenoilisocianato
ES540200A0 (es) Un procedimiento para la preparacion de acidos 7-amino-3-me-til sustituido-3-defem-4-carboxilicos
ES557772A0 (es) Un procedimiento para la preparacion de epipodofilotoxina
ES545298A0 (es) Un procedimiento para la preparacion de 4-amino-2-fenilqui- nolinas
ES553602A0 (es) Un procedimiento para la preparacion de nuevas quinazolindionas
ES557427A0 (es) Un procedimiento para la preparacion de tetrahidroimidazoquinazolinonas
ES553703A0 (es) Un procedimiento para la preparacion de vesiculas de fosfoliptidos.
ES541373A0 (es) Un procedimiento para la preparacion de un compuesto de 2-oxindol-1-carboxamida
ES551508A0 (es) Un procedimiento para la preparacion de nuevas sulfonilureas
ES555298A0 (es) Un procedimiento para la preparacion de nuevos esteroides 11-b-sustituidos.
ES542517A0 (es) Un procedimiento para la preparacion de monoalquil-polial- quilenpoliaminas
ES555670A0 (es) Un procedimiento para la preparacion de hexahidroarilquinolizinas sustituidas.
ES551129A0 (es) Un procedimiento para la preparacion de nuevas 3-alcoxi-2-(n-pirrolidino)-n-pirimidinil- o n-pirazinil-propilaminas
ES544397A0 (es) Un procedimiento para la preparacion de un compuesto
ES552986A0 (es) Un procedimiento para la preparacion de piridazinilimidazolidinonas
ES556807A0 (es) Un procedimiento para la preparacion de nuevos 11-metileno-esteroides.