ES540200A0 - Un procedimiento para la preparacion de acidos 7-amino-3-me-til sustituido-3-defem-4-carboxilicos - Google Patents

Un procedimiento para la preparacion de acidos 7-amino-3-me-til sustituido-3-defem-4-carboxilicos

Info

Publication number
ES540200A0
ES540200A0 ES540200A ES540200A ES540200A0 ES 540200 A0 ES540200 A0 ES 540200A0 ES 540200 A ES540200 A ES 540200A ES 540200 A ES540200 A ES 540200A ES 540200 A0 ES540200 A0 ES 540200A0
Authority
ES
Spain
Prior art keywords
defem
carboxilicos
acidos
til
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES540200A
Other languages
English (en)
Other versions
ES8700861A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES540200A0 publication Critical patent/ES540200A0/es
Publication of ES8700861A1 publication Critical patent/ES8700861A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
ES540200A 1984-02-10 1985-02-07 Un procedimiento para la preparacion de acidos 7-amino-3-me-til sustituido-3-defem-4-carboxilicos Expired ES8700861A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59024110A JPS60169486A (ja) 1984-02-10 1984-02-10 ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法

Publications (2)

Publication Number Publication Date
ES540200A0 true ES540200A0 (es) 1986-11-16
ES8700861A1 ES8700861A1 (es) 1986-11-16

Family

ID=12129194

Family Applications (2)

Application Number Title Priority Date Filing Date
ES540200A Expired ES8700861A1 (es) 1984-02-10 1985-02-07 Un procedimiento para la preparacion de acidos 7-amino-3-me-til sustituido-3-defem-4-carboxilicos
ES554060A Expired ES8800241A1 (es) 1984-02-10 1986-04-16 Un procedimiento para la preparacion de derivados de tri(alquil inferior)sililo

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES554060A Expired ES8800241A1 (es) 1984-02-10 1986-04-16 Un procedimiento para la preparacion de derivados de tri(alquil inferior)sililo

Country Status (5)

Country Link
US (2) US4699980A (es)
EP (1) EP0154417A3 (es)
JP (1) JPS60169486A (es)
KR (1) KR920002869B1 (es)
ES (2) ES8700861A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
ATE177104T1 (de) * 1984-11-23 1999-03-15 Biochemie Gmbh Cephalosporinderivative
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
US5231170A (en) * 1986-08-27 1993-07-27 Paul Averback Antibodies to dense microspheres
EP0300546B1 (en) * 1987-07-10 1995-08-09 Gist-Brocades N.V. Process for the preparation of cephem compounds and cephalosporin derivatives
AT395854B (de) * 1991-05-24 1993-03-25 Biochemie Gmbh Neues verfahren zur herstellung von 7-amino-3azidomethyl-3-cephem-4-carbonsaeure und deren derivate
HK1200096A1 (en) 2011-09-09 2015-07-31 Merck Sharp & Dohme Corp. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140274994A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Stabilizing ceftolozane
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274993A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane-tazobactam pharmaceutical compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5653557B2 (es) * 1973-10-15 1981-12-19
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
GB2069482B (en) * 1980-02-14 1984-04-04 Gist Brocades Nv Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives
EP0156118A1 (en) * 1980-08-29 1985-10-02 Fujisawa Pharmaceutical Co., Ltd. New starting compounds for the preparation of cephem compounds and processes for preparation thereof
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
DE3364700D1 (en) * 1982-05-26 1986-08-28 Lilly Industries Ltd Preparation of penicillin and cephalosporin compounds and novel intermediates useful therein
DE3232391A1 (de) * 1982-08-31 1984-03-01 Bayer Ag, 5090 Leverkusen Polycarbonate mit konjugierte doppelbindungen enthaltenden endgruppen, gegebenenfalls im gemisch mit bekannten aromatischen polycarbonaten, ihre herstellung und ihre verwendung
DE3247613A1 (de) * 1982-12-23 1984-07-05 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316796A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
US4540779A (en) * 1983-06-20 1985-09-10 Eli Lilly And Company Crystalline 7-(R)-amino-3-(1'pyridiniummethyl)-ceph-3-em-4-carboxylate monohydrochloride monohydrate compound
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
US4665168A (en) * 1986-04-14 1987-05-12 Eli Lilly And Company Cephalosporin intermediate

Also Published As

Publication number Publication date
EP0154417A2 (en) 1985-09-11
KR920002869B1 (ko) 1992-04-06
ES8800241A1 (es) 1987-11-01
US4845211A (en) 1989-07-04
ES554060A0 (es) 1987-11-01
EP0154417A3 (en) 1986-06-11
ES8700861A1 (es) 1986-11-16
JPS60169486A (ja) 1985-09-02
US4699980A (en) 1987-10-13
KR850005845A (ko) 1985-09-26

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