EG17928A - Acyltripeptide immunostimulants - Google Patents

Acyltripeptide immunostimulants

Info

Publication number
EG17928A
EG17928A EG201/85A EG20185A EG17928A EG 17928 A EG17928 A EG 17928A EG 201/85 A EG201/85 A EG 201/85A EG 20185 A EG20185 A EG 20185A EG 17928 A EG17928 A EG 17928A
Authority
EG
Egypt
Prior art keywords
acyltripeptide
immunostimulants
acyltripeptide immunostimulants
Prior art date
Application number
EG201/85A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG17928A publication Critical patent/EG17928A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/16—Eight-membered rings
    • C07D313/18—Eight-membered rings not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
EG201/85A 1984-03-30 1985-03-28 Acyltripeptide immunostimulants EG17928A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/595,169 US4565653A (en) 1984-03-30 1984-03-30 Acyltripeptide immunostimulants

Publications (1)

Publication Number Publication Date
EG17928A true EG17928A (en) 1991-08-30

Family

ID=24382038

Family Applications (1)

Application Number Title Priority Date Filing Date
EG201/85A EG17928A (en) 1984-03-30 1985-03-28 Acyltripeptide immunostimulants

Country Status (20)

Country Link
US (1) US4565653A (xx)
EP (1) EP0157572A3 (xx)
JP (1) JPS60224699A (xx)
KR (1) KR870000372B1 (xx)
AU (2) AU552919B2 (xx)
CA (1) CA1270098A (xx)
DD (1) DD239406A5 (xx)
DK (1) DK142485A (xx)
EG (1) EG17928A (xx)
ES (1) ES8605821A1 (xx)
FI (1) FI851271L (xx)
GR (1) GR850783B (xx)
HU (1) HU198086B (xx)
IL (1) IL74758A (xx)
NO (1) NO851278L (xx)
NZ (1) NZ211634A (xx)
PH (1) PH21303A (xx)
PL (1) PL252659A1 (xx)
PT (1) PT80181B (xx)
ZA (1) ZA852335B (xx)

Families Citing this family (59)

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Publication number Priority date Publication date Assignee Title
CA1295784C (en) * 1985-11-25 1992-02-11 James Patrick Rizzi Peptide immunostimulants
JPH0718039B2 (ja) * 1986-03-26 1995-03-01 株式会社豊田自動織機製作所 粉末付加亜鉛めっき鋼板の製造方法
WO1988001613A1 (en) * 1986-08-27 1988-03-10 Pfizer Inc. Crystalline n-(s-3-methylheptanoyl)-d-gamma-glutamyl-glycyl-d-alanine, and processes and intermediates therefor
WO1988001612A1 (en) * 1986-08-27 1988-03-10 Pfizer Inc. Processes and intermediates for n-(s-3-alkyl-heptanoyl)-d-gamma-glutamyl-glycyl-d-alanine
DE3700173A1 (de) * 1987-01-05 1988-07-14 Hoechst Ag Verfahren zur herstellung von lipophilen aminosaeurederivaten sowie lipophile aminosaeurederivate
DE3820528A1 (de) * 1988-06-16 1989-12-21 Bayer Ag Mittel zur insekten- und milbenabwehr
US5185464A (en) * 1989-02-21 1993-02-09 Pfizer Inc. Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor
US5245079A (en) * 1989-02-21 1993-09-14 Pfizer Inc. Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine
US5134225A (en) * 1989-02-21 1992-07-28 Pfizer Inc. Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-D-alanine
US5248820A (en) * 1989-02-21 1993-09-28 Pfizer Inc. Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor
US5136020A (en) * 1989-02-21 1992-08-04 Pfizer Inc. Crystalline n-(s-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor
CA2125679C (en) 1992-10-15 2005-06-28 Ishizuka Masaaki Novel amino acid derivatives
US5798387A (en) * 1992-10-15 1998-08-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Amino acid derivatives
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US7795210B2 (en) * 2001-10-10 2010-09-14 Novo Nordisk A/S Protein remodeling methods and proteins/peptides produced by the methods
US7157277B2 (en) * 2001-11-28 2007-01-02 Neose Technologies, Inc. Factor VIII remodeling and glycoconjugation of Factor VIII
US7399613B2 (en) * 2001-10-10 2008-07-15 Neose Technologies, Inc. Sialic acid nucleotide sugars
US8008252B2 (en) * 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
US7696163B2 (en) 2001-10-10 2010-04-13 Novo Nordisk A/S Erythropoietin: remodeling and glycoconjugation of erythropoietin
WO2004099231A2 (en) * 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
US7173003B2 (en) * 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) * 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
MXPA04012496A (es) * 2002-06-21 2005-09-12 Novo Nordisk Healthcare Ag Glicoformos del factor vii pegilados.
NZ542094A (en) * 2003-03-14 2008-12-24 Neose Technologies Inc Branched polymer conjugates comprising a peptide and water-soluble polymer chains
US8791070B2 (en) 2003-04-09 2014-07-29 Novo Nordisk A/S Glycopegylated factor IX
WO2006127896A2 (en) * 2005-05-25 2006-11-30 Neose Technologies, Inc. Glycopegylated factor ix
EP1613261A4 (en) * 2003-04-09 2011-01-26 Novo Nordisk As INTRA-CELLULAR FORMATION OF PEPTIDE CONJUGATES
AU2004240553A1 (en) 2003-05-09 2004-12-02 Neose Technologies, Inc. Compositions and methods for the preparation of human growth hormone glycosylation mutants
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US8633157B2 (en) * 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
MXPA06005732A (es) * 2003-11-24 2006-08-17 Neose Technologies Inc Eritropoyetina glucopegilada.
US20080305992A1 (en) * 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080318850A1 (en) * 2003-12-03 2008-12-25 Neose Technologies, Inc. Glycopegylated Factor Ix
JP4657219B2 (ja) * 2003-12-03 2011-03-23 バイオジェネリックス アーゲー ＧｌｙｃｏＰＥＧ化された顆粒球コロニー刺激因子
US7956032B2 (en) * 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
US20060040856A1 (en) * 2003-12-03 2006-02-23 Neose Technologies, Inc. Glycopegylated factor IX
CN101072789B (zh) * 2004-01-08 2013-05-15 生物种属学股份公司 肽的o-连接的糖基化
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
EP1799249A2 (en) * 2004-09-10 2007-06-27 Neose Technologies, Inc. Glycopegylated interferon alpha
EP1814573B1 (en) * 2004-10-29 2016-03-09 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
US20100009902A1 (en) * 2005-01-06 2010-01-14 Neose Technologies, Inc. Glycoconjugation Using Saccharyl Fragments
CA2593682C (en) * 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
US20060246544A1 (en) * 2005-03-30 2006-11-02 Neose Technologies,Inc. Manufacturing process for the production of peptides grown in insect cell lines
US9187546B2 (en) * 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
EP1888098A2 (en) * 2005-05-25 2008-02-20 Neose Technologies, Inc. Glycopegylated erythropoietin formulations
US20070105755A1 (en) * 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
JP2009515508A (ja) * 2005-08-19 2009-04-16 ネオス テクノロジーズ インコーポレイテッド グリコｐｅｇ化因子ｖｉｉおよび因子ｖｉｉａ
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
JP2009544327A (ja) * 2006-07-21 2009-12-17 ノヴォ ノルディスク アー／エス Ｏ−結合型グリコシル化配列によるペプチドのグリコシル化
EP2054521A4 (en) * 2006-10-03 2012-12-19 Novo Nordisk As METHODS OF PURIFYING CONJUGATES OF POLYPEPTIDES
AU2007319657B9 (en) * 2006-10-04 2019-10-31 Novo Nordisk A/S Glycerol linked pegylated sugars and glycopeptides
US20080207487A1 (en) * 2006-11-02 2008-08-28 Neose Technologies, Inc. Manufacturing process for the production of polypeptides expressed in insect cell-lines
KR20150064246A (ko) * 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
US20090053167A1 (en) * 2007-05-14 2009-02-26 Neose Technologies, Inc. C-, S- and N-glycosylation of peptides
EP2162535A4 (en) * 2007-06-04 2011-02-23 Novo Nordisk As O-linked glycosylation using N-acetylglucosamine transferases
ES2551123T3 (es) * 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
US8207112B2 (en) * 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
US20100286067A1 (en) * 2008-01-08 2010-11-11 Biogenerix Ag Glycoconjugation of polypeptides using oligosaccharyltransferases
CN101965200B (zh) 2008-02-27 2013-06-19 诺沃-诺迪斯克有限公司 缀合的因子ⅷ分子

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322341A (en) * 1980-05-13 1982-03-30 Fujisawa Pharmaceutical Co Peptide, process for preparation thereof and use thereof
DK156252C (da) * 1979-07-31 1989-12-18 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af di-, tri- eller tetrapeptidderivater eller salte deraf
DE3070278D1 (en) * 1979-10-11 1985-04-18 Fujisawa Pharmaceutical Co Peptides, processes for their preparation and pharmaceutical compositions containing them
GR81332B (xx) * 1980-12-01 1984-12-11 Fujisawa Pharmaceutical Co
US4493794A (en) * 1980-12-31 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Peptide, process for preparation thereof and use thereof

Also Published As

Publication number Publication date
PL252659A1 (en) 1985-11-19
AU5647686A (en) 1986-09-04
PT80181A (en) 1985-04-01
ZA852335B (en) 1986-11-26
FI851271L (fi) 1985-10-01
NO851278L (no) 1985-10-01
EP0157572A3 (en) 1987-01-07
CA1270098A (en) 1990-06-05
KR870000372B1 (ko) 1987-03-06
JPS60224699A (ja) 1985-11-09
GR850783B (xx) 1985-11-25
US4565653A (en) 1986-01-21
ES8605821A1 (es) 1986-04-01
IL74758A0 (en) 1985-06-30
PT80181B (en) 1987-03-20
ES541620A0 (es) 1986-04-01
AU566460B2 (en) 1987-10-22
IL74758A (en) 1988-06-30
DK142485D0 (da) 1985-03-29
DD239406A5 (de) 1986-09-24
KR850006939A (ko) 1985-10-25
DK142485A (da) 1985-10-01
AU552919B2 (en) 1986-06-26
HU198086B (en) 1989-07-28
FI851271A0 (fi) 1985-03-29
EP0157572A2 (en) 1985-10-09
AU4052385A (en) 1985-10-03
PH21303A (en) 1987-09-28
NZ211634A (en) 1988-10-28
HUT37443A (en) 1985-12-28

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