ES535551A0 - Un procedimiento para la preparacion de nuevos 16-fluor-16,17-dideshidro prostanoides. - Google Patents
Un procedimiento para la preparacion de nuevos 16-fluor-16,17-dideshidro prostanoides.Info
- Publication number
- ES535551A0 ES535551A0 ES535551A ES535551A ES535551A0 ES 535551 A0 ES535551 A0 ES 535551A0 ES 535551 A ES535551 A ES 535551A ES 535551 A ES535551 A ES 535551A ES 535551 A0 ES535551 A0 ES 535551A0
- Authority
- ES
- Spain
- Prior art keywords
- prostanoides
- dideshidro
- fluor
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838324004A GB8324004D0 (en) | 1983-09-07 | 1983-09-07 | 16-fluoro-16 17-didehydro prostanoids |
Publications (2)
Publication Number | Publication Date |
---|---|
ES535551A0 true ES535551A0 (es) | 1986-05-16 |
ES8607022A1 ES8607022A1 (es) | 1986-05-16 |
Family
ID=10548451
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES535551A Expired ES8607022A1 (es) | 1983-09-07 | 1984-08-30 | Un procedimiento para la preparacion de nuevos 16-fluor-16,17-dideshidro prostanoides. |
ES543776A Expired ES8604135A1 (es) | 1983-09-07 | 1985-05-31 | Un procedimiento para la preparacion de nuevos 16-fluor-16, 17-dideshidro prostanoides |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543776A Expired ES8604135A1 (es) | 1983-09-07 | 1985-05-31 | Un procedimiento para la preparacion de nuevos 16-fluor-16, 17-dideshidro prostanoides |
Country Status (24)
Country | Link |
---|---|
US (1) | US4626597A (es) |
JP (1) | JPS6072859A (es) |
KR (1) | KR850002830A (es) |
AU (1) | AU562725B2 (es) |
BE (1) | BE900414A (es) |
CH (1) | CH662114A5 (es) |
CS (1) | CS259869B2 (es) |
DE (1) | DE3430626A1 (es) |
DK (1) | DK406484A (es) |
ES (2) | ES8607022A1 (es) |
FI (1) | FI843285A (es) |
FR (1) | FR2551436B1 (es) |
GB (2) | GB8324004D0 (es) |
GR (1) | GR80204B (es) |
HU (1) | HU192430B (es) |
IL (1) | IL72749A (es) |
IT (1) | IT1180210B (es) |
NL (1) | NL8402666A (es) |
NO (1) | NO843355L (es) |
NZ (1) | NZ209294A (es) |
PT (1) | PT79113B (es) |
SE (1) | SE8404334L (es) |
SU (1) | SU1442070A3 (es) |
ZA (1) | ZA846580B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8625326D0 (en) * | 1986-10-22 | 1986-11-26 | Glaxo Group Ltd | Medicaments |
GB2210556B (en) * | 1987-10-02 | 1991-07-17 | Ueno Seiyaku Oyo Kenkyujo Kk | The use of 15-keto-16-halo-prostaglandins in cathartic compositions |
US5317032A (en) * | 1987-10-02 | 1994-05-31 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Prostaglandin cathartic |
AU616564B2 (en) * | 1988-09-29 | 1991-10-31 | Sumitomo Chemical Company, Limited | Novel pyrazole compounds, method for production thereof, use thereof and intermediates for production thereof |
US5099644A (en) * | 1990-04-04 | 1992-03-31 | General Electric Company | Lean staged combustion assembly |
ES2159889T3 (es) | 1996-11-12 | 2001-10-16 | Alcon Lab Inc | 15-fluoro prostaglandinas utilizadas como hipotensores oculares. |
US6680339B2 (en) | 1996-11-12 | 2004-01-20 | Alcon Manufacturing, Ltd. | 15-fluoro prostaglandins as ocular hypotensives |
EP1480949B1 (en) * | 2002-03-01 | 2015-04-29 | Allergan, Inc. | Preparation of prostamides |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3987087A (en) * | 1971-07-29 | 1976-10-19 | The Upjohn Company | Phenyl-substituted prostaglandin-f type analogs |
GB1396206A (en) * | 1972-04-27 | 1975-06-04 | Upjohn Co | Prostaglandins and the preparation thereof |
ZA744580B (en) * | 1973-07-20 | 1975-07-30 | Upjohn Co | Prostaglandin analogs |
US4059576A (en) * | 1973-08-06 | 1977-11-22 | Hoffmann-La Roche, Inc. | 11-Substituted prostaglandins |
GB1484591A (en) * | 1974-04-11 | 1977-09-01 | Ono Pharmaceutical Co | Prostaglandin compositions |
AU501803B2 (en) * | 1975-03-21 | 1979-06-28 | Farmitalia Carlo Erba S.P.A. | Fluoro-prostaglandins |
US4283417A (en) * | 1976-06-14 | 1981-08-11 | Pfizer Inc. | Bronchodialation with 13,14-dihydro-15-alkenyl prostaglandins |
US4268522A (en) * | 1976-06-14 | 1981-05-19 | Pfizer Inc. | 13,14-Dihydro-15-alkenyl- and 13,14-dihydro-15-alkynyl prostaglandins and analogs thereof |
-
1983
- 1983-09-07 GB GB838324004A patent/GB8324004D0/en active Pending
-
1984
- 1984-08-01 IT IT22159/84A patent/IT1180210B/it active
- 1984-08-20 GB GB08421124A patent/GB2146325B/en not_active Expired
- 1984-08-20 FI FI843285A patent/FI843285A/fi not_active Application Discontinuation
- 1984-08-20 DE DE19843430626 patent/DE3430626A1/de not_active Withdrawn
- 1984-08-21 AU AU32231/84A patent/AU562725B2/en not_active Ceased
- 1984-08-21 NZ NZ209294A patent/NZ209294A/en unknown
- 1984-08-21 FR FR8413013A patent/FR2551436B1/fr not_active Expired
- 1984-08-22 CH CH4020/84A patent/CH662114A5/de not_active IP Right Cessation
- 1984-08-22 NO NO843355A patent/NO843355L/no unknown
- 1984-08-22 US US06/643,014 patent/US4626597A/en not_active Expired - Fee Related
- 1984-08-22 PT PT79113A patent/PT79113B/pt unknown
- 1984-08-22 CS CS846360A patent/CS259869B2/cs unknown
- 1984-08-22 IL IL72749A patent/IL72749A/xx unknown
- 1984-08-23 ZA ZA846580A patent/ZA846580B/xx unknown
- 1984-08-23 BE BE0/213533A patent/BE900414A/fr not_active IP Right Cessation
- 1984-08-24 GR GR80204A patent/GR80204B/el unknown
- 1984-08-24 KR KR1019840005144A patent/KR850002830A/ko not_active Application Discontinuation
- 1984-08-24 DK DK406484A patent/DK406484A/da not_active Application Discontinuation
- 1984-08-28 JP JP59177631A patent/JPS6072859A/ja active Pending
- 1984-08-30 ES ES535551A patent/ES8607022A1/es not_active Expired
- 1984-08-30 SE SE8404334A patent/SE8404334L/xx not_active Application Discontinuation
- 1984-08-31 HU HU843291A patent/HU192430B/hu unknown
- 1984-08-31 NL NL8402666A patent/NL8402666A/nl not_active Application Discontinuation
-
1985
- 1985-05-31 ES ES543776A patent/ES8604135A1/es not_active Expired
- 1985-10-10 SU SU853961258A patent/SU1442070A3/ru active
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