ES537783A0 - Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos. - Google Patents

Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos.

Info

Publication number
ES537783A0
ES537783A0 ES537783A ES537783A ES537783A0 ES 537783 A0 ES537783 A0 ES 537783A0 ES 537783 A ES537783 A ES 537783A ES 537783 A ES537783 A ES 537783A ES 537783 A0 ES537783 A0 ES 537783A0
Authority
ES
Spain
Prior art keywords
dihidrobenzufuranos
analagos
hydroxy
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES537783A
Other languages
English (en)
Other versions
ES8602734A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES8602734A1 publication Critical patent/ES8602734A1/es
Publication of ES537783A0 publication Critical patent/ES537783A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
ES537783A 1983-11-21 1984-11-20 Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos. Granted ES537783A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/553,668 US4563476A (en) 1983-11-21 1983-11-21 Substituted 5-hydroxy-2,3-dihydrobenzofurans and analogs thereof useful as anti-inflammatory agents

Publications (2)

Publication Number Publication Date
ES8602734A1 ES8602734A1 (es) 1985-12-01
ES537783A0 true ES537783A0 (es) 1985-12-01

Family

ID=24210278

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537783A Granted ES537783A0 (es) 1983-11-21 1984-11-20 Un procedimiento para la preparacion de nuevos 5-hidroxi-2,3-dihidrobenzufuranos sustituidos y analagos.

Country Status (7)

Country Link
US (1) US4563476A (es)
EP (1) EP0150291B1 (es)
JP (1) JPS60149576A (es)
CA (1) CA1261333A (es)
DE (1) DE3477194D1 (es)
DK (1) DK549284A (es)
ES (1) ES537783A0 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966907A (en) * 1988-08-12 1990-10-30 Merck & Co., Inc. 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
US4975457A (en) * 1989-09-25 1990-12-04 Merck & Co., Inc. Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
GB2262524A (en) * 1991-12-18 1993-06-23 Sandoz Ltd Pharmaceutically active 2-hydroxy-benzylamines
FR2720395B1 (fr) * 1994-05-31 1996-06-28 Oreal Nouveaux composés de la famille des benzohétérocycles.
US7504228B2 (en) * 2001-06-05 2009-03-17 Qlt Inc. Integrin linked kinase modulation of monocyte activation
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
CA2969926C (en) 2009-02-20 2018-05-15 2-Bbb Medicines B.V. Glutathione-based drug delivery system
EP4218718A3 (en) 2009-05-06 2024-04-24 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH567011A5 (es) * 1972-12-19 1975-09-30 Eisai Co Ltd
FR2244458A1 (en) * 1973-09-20 1975-04-18 Bottu Benzofuran derivs - useful as anti-inflammatories and analgesics
JPS5942300B2 (ja) * 1975-04-24 1984-10-13 富士写真フイルム株式会社 色画像耐光堅牢化方法
FR2353291A1 (fr) * 1976-05-31 1977-12-30 Parcor Nouveaux derives du benzofuranne
ZA824343B (en) * 1981-07-01 1983-04-27 Upjohn Co Pyridinyl- and imidazolyl-benzofurane and benzothiophenes

Also Published As

Publication number Publication date
US4563476A (en) 1986-01-07
ES8602734A1 (es) 1985-12-01
EP0150291B1 (en) 1989-03-15
DK549284D0 (da) 1984-11-20
CA1261333A (en) 1989-09-26
JPS60149576A (ja) 1985-08-07
DE3477194D1 (en) 1989-04-20
EP0150291A1 (en) 1985-08-07
DK549284A (da) 1985-07-03

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