DK549284A - 5-hydroxy-2,3-dihydrobenzofuranforbindelse, farmaceutisk praeparatindeholdende en saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse - Google Patents

5-hydroxy-2,3-dihydrobenzofuranforbindelse, farmaceutisk praeparatindeholdende en saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse

Info

Publication number
DK549284A
DK549284A DK549284A DK549284A DK549284A DK 549284 A DK549284 A DK 549284A DK 549284 A DK549284 A DK 549284A DK 549284 A DK549284 A DK 549284A DK 549284 A DK549284 A DK 549284A
Authority
DK
Denmark
Prior art keywords
connection
hydroxy
preparing
procedure
pharmaceutical preparation
Prior art date
Application number
DK549284A
Other languages
English (en)
Other versions
DK549284D0 (da
Inventor
Michael N Chang
Milton L Hammond
Norman P Jensen
Robert A Zambias
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK549284D0 publication Critical patent/DK549284D0/da
Publication of DK549284A publication Critical patent/DK549284A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
DK549284A 1983-11-21 1984-11-20 5-hydroxy-2,3-dihydrobenzofuranforbindelse, farmaceutisk praeparatindeholdende en saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse DK549284A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/553,668 US4563476A (en) 1983-11-21 1983-11-21 Substituted 5-hydroxy-2,3-dihydrobenzofurans and analogs thereof useful as anti-inflammatory agents

Publications (2)

Publication Number Publication Date
DK549284D0 DK549284D0 (da) 1984-11-20
DK549284A true DK549284A (da) 1985-07-03

Family

ID=24210278

Family Applications (1)

Application Number Title Priority Date Filing Date
DK549284A DK549284A (da) 1983-11-21 1984-11-20 5-hydroxy-2,3-dihydrobenzofuranforbindelse, farmaceutisk praeparatindeholdende en saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse

Country Status (7)

Country Link
US (1) US4563476A (da)
EP (1) EP0150291B1 (da)
JP (1) JPS60149576A (da)
CA (1) CA1261333A (da)
DE (1) DE3477194D1 (da)
DK (1) DK549284A (da)
ES (1) ES8602734A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966907A (en) * 1988-08-12 1990-10-30 Merck & Co., Inc. 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
US4975457A (en) * 1989-09-25 1990-12-04 Merck & Co., Inc. Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
GB2262524A (en) * 1991-12-18 1993-06-23 Sandoz Ltd Pharmaceutically active 2-hydroxy-benzylamines
FR2720395B1 (fr) * 1994-05-31 1996-06-28 Oreal Nouveaux composés de la famille des benzohétérocycles.
US7504228B2 (en) * 2001-06-05 2009-03-17 Qlt Inc. Integrin linked kinase modulation of monocyte activation
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH567011A5 (da) * 1972-12-19 1975-09-30 Eisai Co Ltd
FR2244458A1 (en) * 1973-09-20 1975-04-18 Bottu Benzofuran derivs - useful as anti-inflammatories and analgesics
JPS5942300B2 (ja) * 1975-04-24 1984-10-13 富士写真フイルム株式会社 色画像耐光堅牢化方法
FR2353291A1 (fr) * 1976-05-31 1977-12-30 Parcor Nouveaux derives du benzofuranne
ZA824343B (en) * 1981-07-01 1983-04-27 Upjohn Co Pyridinyl- and imidazolyl-benzofurane and benzothiophenes

Also Published As

Publication number Publication date
US4563476A (en) 1986-01-07
ES537783A0 (es) 1985-12-01
EP0150291B1 (en) 1989-03-15
DE3477194D1 (en) 1989-04-20
JPS60149576A (ja) 1985-08-07
CA1261333A (en) 1989-09-26
EP0150291A1 (en) 1985-08-07
DK549284D0 (da) 1984-11-20
ES8602734A1 (es) 1985-12-01

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