ES534025A0 - Un metodo de produccion de un acido nucleico inmovilizado. - Google Patents

Un metodo de produccion de un acido nucleico inmovilizado.

Info

Publication number
ES534025A0
ES534025A0 ES534025A ES534025A ES534025A0 ES 534025 A0 ES534025 A0 ES 534025A0 ES 534025 A ES534025 A ES 534025A ES 534025 A ES534025 A ES 534025A ES 534025 A0 ES534025 A0 ES 534025A0
Authority
ES
Spain
Prior art keywords
production
nucleic acid
immobilized nucleic
immobilized
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES534025A
Other languages
English (en)
Other versions
ES8607387A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Diagnostics Inc
Original Assignee
Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/511,064 external-priority patent/US4542102A/en
Application filed by Molecular Diagnostics Inc filed Critical Molecular Diagnostics Inc
Publication of ES8607387A1 publication Critical patent/ES8607387A1/es
Publication of ES534025A0 publication Critical patent/ES534025A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
ES534025A 1983-07-05 1984-07-04 Un metodo de produccion de un acido nucleico inmovilizado. Expired ES8607387A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/511,064 US4542102A (en) 1983-07-05 1983-07-05 Coupling of nucleic acids to solid support by photochemical methods
US06/611,667 US4713326A (en) 1983-07-05 1984-05-18 Coupling of nucleic acids to solid support by photochemical methods

Publications (2)

Publication Number Publication Date
ES8607387A1 ES8607387A1 (es) 1986-05-16
ES534025A0 true ES534025A0 (es) 1986-05-16

Family

ID=27057111

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534025A Expired ES8607387A1 (es) 1983-07-05 1984-07-04 Un metodo de produccion de un acido nucleico inmovilizado.

Country Status (7)

Country Link
US (1) US4713326A (es)
EP (1) EP0130523B1 (es)
JP (1) JPH075628B2 (es)
AU (1) AU563558B2 (es)
DE (1) DE3471689D1 (es)
ES (1) ES8607387A1 (es)
IL (1) IL72278A (es)

Families Citing this family (185)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994373A (en) 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4849077A (en) * 1984-08-06 1989-07-18 Akademie Der Wissenschaften Der Ddr Process for solid phase-sequencing of nucleic acid fragments
GB2179448B (en) * 1984-12-19 1989-06-07 Blair Malcolm A D Improved sandwich hybridisation technique for the detection of nucleotide sequences
GB8432118D0 (en) * 1984-12-19 1985-01-30 Malcolm A D B Sandwich hybridisation technique
AU5698186A (en) * 1985-03-15 1986-10-13 Summerton, J. Polynucleotide assay reagent and method
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
CA1313485C (en) * 1986-03-04 1993-02-09 Angenics, Inc. Detection of nucleic acid sequences using particle agglutination
US5348855A (en) * 1986-03-05 1994-09-20 Miles Inc. Assay for nucleic acid sequences in an unpurified sample
FR2606155B1 (fr) * 1986-11-05 1990-07-20 Pasteur Institut Reactif immunologique pour la determination de la sequence d'un acide nucleique, son procede de preparation et methode immunologique de determination de la sequence d'un acide nucleique a l'aide de ce reactif
FR2606154B1 (fr) * 1986-11-05 1990-05-11 Pasteur Institut Procede de detection et de dosage immunologique des acides nucleiques presents dans les milieux biologiques
US5599667A (en) * 1987-03-02 1997-02-04 Gen-Probe Incorporated Polycationic supports and nucleic acid purification separation and hybridization
JPH01125395A (ja) * 1987-07-29 1989-05-17 Life Technol Inc 核酸浦獲試薬
US4942124A (en) * 1987-08-11 1990-07-17 President And Fellows Of Harvard College Multiplex sequencing
DK641487A (da) * 1987-12-07 1989-06-08 Gluetech Aps Fremgangsmaade til modificering af polymeroverflader
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US7811751B2 (en) 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
US6054270A (en) * 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
AU632494B2 (en) * 1988-05-20 1993-01-07 F. Hoffmann-La Roche Ag Immobilized sequence-specific probes
WO1990001563A1 (en) * 1988-08-01 1990-02-22 Cimino George D Identification of allele specific nucleic acid sequences by hybridization with crosslinkable oligonucleotide probes
US5985327A (en) 1988-10-05 1999-11-16 Flinders Technologies Pty. Ltd. Solid medium and method for DNA storage
US5756126A (en) * 1991-05-29 1998-05-26 Flinders Technologies Pty. Ltd. Dry solid medium for storage and analysis of genetic material
US5496562A (en) * 1988-10-05 1996-03-05 Flinders Technologies Pty Ltd Solid medium and method for DNA storage
US5807527A (en) * 1991-05-29 1998-09-15 Flinders Technologies Pty. Ltd. Solid medium and method for DNA storage
US5972386A (en) * 1995-12-19 1999-10-26 Flinders Technologies Pty, Ltd. Dry solid medium for storage and analysis of genetic material
US6447804B1 (en) 1988-10-05 2002-09-10 Whatman, Plc Dry solid medium for storage and analysis of genetic material
WO1990003959A1 (en) * 1988-10-05 1990-04-19 The Flinders University Of South Australia Solid medium and method for dna storage
US6627226B2 (en) 1988-10-05 2003-09-30 Whatman, Inc. Dry solid medium for storage and analysis of genetic material
JP3046838B2 (ja) * 1989-03-10 2000-05-29 バイシス・インコーポレーテツド 親和性捕捉法の妨害の防止
US6919211B1 (en) 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
US6379895B1 (en) 1989-06-07 2002-04-30 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US6406844B1 (en) 1989-06-07 2002-06-18 Affymetrix, Inc. Very large scale immobilized polymer synthesis
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US6955915B2 (en) 1989-06-07 2005-10-18 Affymetrix, Inc. Apparatus comprising polymers
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6309822B1 (en) 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US5871928A (en) * 1989-06-07 1999-02-16 Fodor; Stephen P. A. Methods for nucleic acid analysis
US5547839A (en) * 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods
US6506558B1 (en) 1990-03-07 2003-01-14 Affymetrix Inc. Very large scale immobilized polymer synthesis
EP0562047A4 (en) 1990-12-06 1995-11-02 Affymax Tech Nv Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
CA2065719A1 (en) 1991-04-30 1992-10-31 John B. Findlay Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle
EP0773227A1 (en) * 1991-09-18 1997-05-14 Affymax Technologies N.V. Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides
US5639603A (en) * 1991-09-18 1997-06-17 Affymax Technologies N.V. Synthesizing and screening molecular diversity
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6864101B1 (en) 1991-11-22 2005-03-08 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6468740B1 (en) 1992-11-05 2002-10-22 Affymetrix, Inc. Cyclic and substituted immobilized molecular synthesis
ATE160222T1 (de) 1992-07-06 1997-11-15 Biomira Inc Photoaktivierung von proteinen zu konjugationszwecken
US5767259A (en) 1994-12-27 1998-06-16 Naxcor Oligonucleotides containing base-free linking groups with photoactivatable side chains
US6277570B1 (en) 1993-04-13 2001-08-21 Naxcor Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
US6495676B1 (en) * 1993-04-13 2002-12-17 Naxcor Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
CA2159356A1 (en) * 1993-04-13 1994-10-27 Michael L. Wood Non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
US6087186A (en) 1993-07-16 2000-07-11 Irori Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
US5503805A (en) * 1993-11-02 1996-04-02 Affymax Technologies N.V. Apparatus and method for parallel coupling reactions
US6165778A (en) * 1993-11-02 2000-12-26 Affymax Technologies N.V. Reaction vessel agitation apparatus
US7378236B1 (en) 1994-06-17 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Method for analyzing gene expression patterns
US7625697B2 (en) * 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US7323298B1 (en) * 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
US5622822A (en) 1994-09-13 1997-04-22 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using polyethyleneimine and an anionic phosphate ester surfactant and amplification of same
US5582988A (en) 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5747256A (en) * 1995-12-19 1998-05-05 Beckman Instruments, Inc. Homogeneous DNA probe titration assay
US20070178475A1 (en) * 1998-09-17 2007-08-02 Nehls Michael C Novel human polynucleotides and polypeptides encoded thereby
US6545264B1 (en) 1998-10-30 2003-04-08 Affymetrix, Inc. Systems and methods for high performance scanning
US6303799B1 (en) 1998-11-10 2001-10-16 Naxcor Polynucleotide crosslinking agents
US6570003B1 (en) * 2001-01-09 2003-05-27 Lexion Genetics Incorporated Human 7TM proteins and polynucleotides encoding the same
US20020110809A1 (en) * 1999-04-30 2002-08-15 Nehls Michael C. Novel human polynucleotides and polypeptides encoded thereby
US20020095031A1 (en) * 1999-05-04 2002-07-18 Nehls Michael C. Novel human polynucleotides and polypeptides encoded thereby
ES2228520T3 (es) * 1999-05-04 2005-04-16 Ortho-Clinical Diagnostics, Inc. Capatura rapida y eficaz de adn de una muestra sin usar reactivo de lisis celular.
US20030050464A1 (en) * 2000-07-28 2003-03-13 Yi Hu Novel human proteases and polynucleotides encoding the same
US20080003673A1 (en) * 1999-09-02 2008-01-03 Alejandro Abuin Novel human proteases and polynucleotides encoding the same
US20010034437A1 (en) * 2000-01-06 2001-10-25 Walke D. Wade Novel human proteases and polynucleotides encoding the same
US7374933B2 (en) * 2000-04-12 2008-05-20 Lexicon Pharmaceuticals, Inc. Human metalloprotease and polynucleotides encoding the same
US20050153323A1 (en) * 2000-07-28 2005-07-14 Yi Hu Novel human proteases and polynucleotides encoding the same
US6448388B1 (en) 2000-08-16 2002-09-10 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
US6716614B1 (en) 1999-09-02 2004-04-06 Lexicon Genetics Incorporated Human calcium dependent proteases, polynucleotides encoding the same, and uses thereof
US20030166902A1 (en) * 2001-02-20 2003-09-04 Yi Hu Novel human protease and polynucleotides encoding the same
US6867291B1 (en) * 2000-09-15 2005-03-15 Lexicon Genetics Incorporated Human hemicentin proteins and polynucleotides encoding the same
US6790660B1 (en) 2001-09-18 2004-09-14 Lexicon Genetics Incorporated Human kielin-like proteins and polynucleotides encoding the same
US20020107382A1 (en) * 2000-09-27 2002-08-08 Friddle Carl Johan Novel human protease inhibitor proteins and polynucleotides encoding the same
US6541252B1 (en) 2000-05-19 2003-04-01 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6511840B1 (en) 2000-06-15 2003-01-28 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US6586230B1 (en) 2000-10-27 2003-07-01 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6579710B2 (en) * 2000-12-12 2003-06-17 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US20080050809A1 (en) * 1999-09-28 2008-02-28 Alejandro Abuin Novel human kinases and polynucleotides encoding the same
US6841377B1 (en) * 2001-06-13 2005-01-11 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6734010B2 (en) * 2001-05-09 2004-05-11 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6797510B1 (en) * 2001-05-24 2004-09-28 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6750054B2 (en) 2000-05-18 2004-06-15 Lexicon Genetics Incorporated Human semaphorin homologs and polynucleotides encoding the same
US20080213878A1 (en) * 1999-10-19 2008-09-04 Gregory Donoho Novel human membrane proteins and polynucleotides encoding the same
EP1244694A2 (en) * 1999-12-07 2002-10-02 Lexicon Genetics Incorporated Putative human g-protein coupled receptors
EP1240187A2 (en) 1999-12-07 2002-09-18 Lexicon Genetics Incorporated Novel human kinase proteins and polynucleotides encoding the same
EP1235909A1 (en) 1999-12-09 2002-09-04 Lexicon Genetics Incorporated Human adam-ts proteases and polynucleotides encoding the same
US6692947B2 (en) * 1999-12-13 2004-02-17 Lexicon Genetics Incorporated Human transferase proteins and polynucleotides encoding the same
EP1250427A2 (en) * 1999-12-22 2002-10-23 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encodingthe same having homology to cd20 proteins and ige receptors
WO2001046407A1 (en) * 1999-12-22 2001-06-28 Lexicon Genetics Incorporated Polynucleotides encoding human protease homologs
AU2001229318A1 (en) * 2000-01-12 2001-07-24 Lexicon Genetics Incorporated Human olfactory receptor and polynucleotides encoding the same
AU784106B2 (en) * 2000-01-18 2006-02-02 Lexicon Pharmaceuticals, Inc. Human GABA receptor proteins and polynucleotides encoding the same
AU784540B2 (en) * 2000-01-18 2006-04-27 Lexicon Pharmaceuticals, Inc. Novel human kinase protein and polynucleotides encoding the same
JP2004500084A (ja) * 2000-01-26 2004-01-08 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトニューレキシン様タンパク質及び該タンパク質をコードするポリヌクレオチド
EP1301600A2 (en) * 2000-01-28 2003-04-16 Lexicon Genetics Incorporated Human enzymes and polynucleotides encoding the same
JP2003520607A (ja) * 2000-01-28 2003-07-08 レキシコン・ジェネティクス・インコーポレーテッド ヒト膜タンパクおよびそれをコードするポリヌクレオチド
AU3665901A (en) * 2000-02-04 2001-08-14 Lexicon Genetics Incorporated Novel human enzymes and polynucleotides encoding the same
EP1257579B1 (en) * 2000-02-04 2009-08-05 Lexicon Pharmaceuticals, Inc. Novel human g protein coupled receptor proteins and polynucleotides encoding the same
EP1255843A1 (en) 2000-02-11 2002-11-13 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
AU2001238503A1 (en) * 2000-02-17 2001-08-27 Lexicon Genetics Incorporated Novel human thrombospondin repeat proteins and polynucleotides encoding the same
JP2003531582A (ja) * 2000-02-29 2003-10-28 レキシコン・ジェネティクス・インコーポレーテッド ヒトトランスポータータンパクおよびそれをコードするポリヌクレオチド
AU2001245370A1 (en) 2000-02-29 2001-09-12 Lexicon Genetics Incorporated Novel human transferase proteins and polynucleotides encoding the same
AU2001247283A1 (en) * 2000-03-06 2001-09-17 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
WO2001068869A2 (en) 2000-03-10 2001-09-20 Lexicon Genetics Incorporated Human g-coupled protein receptor kinsaes and polynucleotides encoding the same
AU2001247395B2 (en) * 2000-03-13 2006-08-31 Lexicon Pharmaceuticals, Inc. Novel human phospholipases and polynucleotides encoding the same
AU2001245871B2 (en) * 2000-03-20 2006-06-01 Lexicon Pharmaceuticals, Inc. Novel human secreted proteins and polynucleotides encoding the same
JP2004505610A (ja) * 2000-04-03 2004-02-26 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトイオンチャンネルタンパク質およびそれをコードするポリヌクレオチド
AU2001257195B2 (en) 2000-04-25 2006-10-05 Lexicon Pharmaceuticals, Inc. Novel human kinase proteins and polynucleotides encoding the same
US7262006B1 (en) 2000-05-01 2007-08-28 Ortho-Clinical Diagnostics, Inc. Rapid and efficient capture of DNA from sample without using cell lysing reagent
AU2001263107A1 (en) * 2000-05-12 2001-11-26 Lexicon Genetics Incorporated Novel human lipocalin homologs and polynucleotides encoding the same
WO2001090179A2 (en) * 2000-05-23 2001-11-29 Lexicon Genetics Incorporated Novel human thrombospondin-like proteins and polynucleotides encoding the same
US6790667B1 (en) 2000-05-30 2004-09-14 Lexicon Genetics Incorporated Human mitochondrial proteins and polynucleotides encoding the same
AU2001275337A1 (en) * 2000-06-07 2001-12-17 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
US20040168209A1 (en) * 2000-06-12 2004-08-26 Alejandro Abuin Novel murine polynucleotide sequences and mutant cells and mutant animals defined thereby
WO2002000720A2 (en) * 2000-06-27 2002-01-03 Lexicon Genetics Incorporated Novel human gaba receptors and polynucleotides encoding the same
AU2002224553A1 (en) * 2000-07-21 2002-02-05 Incyte Genomics, Inc. Human proteases
US6887685B1 (en) * 2000-07-25 2005-05-03 Lexicon Genetics Incorporated Human thymosin protein and polynucleotides encoding the same
US20020076780A1 (en) * 2000-08-16 2002-06-20 Turner C. Alexander Novel human ion channel proteins and polynucleotides encoding the same
AU2001286792A1 (en) * 2000-08-22 2002-03-04 Lexicon Genetics Incorporated Novel human 7TM proteins and polynucleotides encoding the same
JP2004531201A (ja) * 2000-08-22 2004-10-14 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトプロテアーゼ及び該プロテアーゼをコードするポリヌクレオチド
AU2001285326A1 (en) * 2000-08-31 2002-03-13 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
WO2002020753A2 (en) * 2000-09-01 2002-03-14 Lexicon Genetics Incorporated Human gaba transporter protein and polynucleotides encoding the same
JP2004509641A (ja) * 2000-09-27 2004-04-02 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトイオン交換タンパク質およびそれをコードするポリヌクレオチド
US6777232B1 (en) * 2000-10-02 2004-08-17 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encoding the same
WO2002031129A2 (en) 2000-10-12 2002-04-18 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US7001763B1 (en) 2000-10-17 2006-02-21 Lexicon Genetics Incorporated Human semaphorin proteins and polynucleotides encoding the same
EP1624062A3 (en) * 2000-10-27 2006-02-22 Lexicon Genetics Incorporated Human 7tm proteins and polynucleotides encoding them
EP1330524A2 (en) * 2000-10-30 2003-07-30 Lexicon Genetics Incorporated Novel human 7tm proteins and polynucleotides encoding the same
CA2427828A1 (en) * 2000-11-01 2002-05-10 Lexicon Genetics Incorporated Novel human proteases and polynucleotides encoding the same
JP2004535154A (ja) * 2000-11-15 2004-11-25 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒト分泌タンパク質およびそれをコードするポリヌクレオチド
WO2002042438A2 (en) * 2000-11-20 2002-05-30 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6384979B1 (en) 2000-11-30 2002-05-07 The University Of British Columbia Color filtering and absorbing total internal reflection image display
JP2004517622A (ja) * 2000-12-11 2004-06-17 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼ及び該キナーゼをコードするポリヌクレオチド
US6583269B1 (en) 2000-12-18 2003-06-24 Lexicon Genetics Incorporated Human protease inhibitor and polynucleotides encoding the same
US6852844B1 (en) 2000-12-20 2005-02-08 Lexicon Genetics Incorporated Human protocadherin proteins and polynucleotides encoding the same
JP2005502307A (ja) * 2000-12-20 2005-01-27 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトイオンチャンネルタンパクおよびそれをコードするポリヌクレオチド
AU2002246858A1 (en) * 2000-12-27 2002-08-06 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
WO2002068626A2 (en) * 2000-12-28 2002-09-06 Lexicon Genetics Incorporated Novel human ion channel-related proteins and polynucleotides encoding the same
US20020115844A1 (en) * 2001-01-05 2002-08-22 Yu Xuanchuan Sean Novel human lipase and polynucleotides encoding the same
AU2002236717A1 (en) * 2001-01-08 2002-07-16 Lexicon Genetics Incorporated Human protease and polynucleotides encoding the same
CA2434896A1 (en) * 2001-01-23 2002-08-01 Lexicon Genetics Incorporated Novel human kinases and polynucleotides encoding the same
CA2434897A1 (en) * 2001-01-24 2002-08-01 Lexicon Genetics Incorporated Human lipase and polynucleotides encoding the same
WO2002063002A2 (en) * 2001-02-02 2002-08-15 Lexicon Genetics Incorporated Novel human transporter protein and polynucleotides encoding the same
JP3929250B2 (ja) * 2001-03-08 2007-06-13 株式会社ルネサステクノロジ 半導体装置
WO2002072774A2 (en) * 2001-03-12 2002-09-19 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
US7252990B2 (en) * 2001-03-12 2007-08-07 Lexicon Genetics Incorporated Human dectin proteins and polynucleotides encoding the same
JP2004535781A (ja) * 2001-03-12 2004-12-02 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトｅｆｇファミリータンパクおよびそれをコードするポリヌクレオチド
US6994995B1 (en) * 2001-03-16 2006-02-07 Lexicon Genetics Incorporated Human synaptotagmin and polynucleotides encoding the same
WO2002074932A2 (en) 2001-03-20 2002-09-26 Lexicon Genetics Incorporated Novel human kinase and polynucleotides encoding the same
EP1383880A1 (en) * 2001-04-06 2004-01-28 Lexicon Genetics Incorporated Novel human kinase and polynucleotides encoding the same
EP1383879A4 (en) * 2001-04-06 2005-05-11 Lexicon Genetics Inc HUMAN KINASES AND POLYNUCLEOTIDES ENCODING SAME
US6644173B2 (en) * 2001-04-11 2003-11-11 Keuring, Incorporated Beverage filter cartridge holder
US6607895B2 (en) 2001-04-16 2003-08-19 Lexicon Genetics Incorporated Human adenylsuccinate synthetase and polynucleotides encoding the same
WO2002088313A2 (en) * 2001-04-30 2002-11-07 Lexicon Genetics Incorporated Novel human nuclear transporters and polynucleotides encoding the same
DE10121201B4 (de) * 2001-04-30 2007-07-12 Molecular Machines & Industries Gmbh Photoaktivierbare Polysaccharidderivate für die Immobilisierung von Biomolekülen
WO2002097095A1 (en) * 2001-05-25 2002-12-05 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
CA2448347C (en) 2001-05-29 2010-09-21 Lexicon Genetics Incorporated Novel human hydroxylases and polynucleotides encoding the same
JP2004531268A (ja) * 2001-06-14 2004-10-14 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトトランスポータータンパクおよびそれをコードするポリヌクレオチド
WO2003004609A2 (en) * 2001-07-03 2003-01-16 Lexicon Genetics Incorporated Novel human kielin-like proteins and polynucleotides encoding the same
CA2457298A1 (en) * 2001-08-14 2003-02-27 Lexicon Genetics Incorporated Novel human collagen proteins and polynucleotides encoding the same
US20040106109A1 (en) * 2001-10-02 2004-06-03 Belly Robert T Detection of ras mutations
DE10154291B4 (de) * 2001-11-05 2005-05-19 Hain Lifescience Gmbh Verfahren zum Nachweis von Nukleinsäuren in Form eines Trockenschnelltestes
JP3447009B1 (ja) * 2002-10-29 2003-09-16 實 平垣 構築物用構成体およびその製造方法
SE527200C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser av formaterol och fluticason
WO2005023993A2 (en) 2003-09-09 2005-03-17 Integrigen, Inc. Methods and compositions for generation of germline human antibody genes
ATE497837T1 (de) 2004-04-09 2011-02-15 Vivebio Llc Vorrichtungen und verfahren für abnahme, lagerung und transport von biologischen proben
KR100745750B1 (ko) * 2005-01-25 2007-08-02 삼성전자주식회사 인터컬레이터를 이용한 핵산의 분리 방법
US7402730B1 (en) 2005-02-03 2008-07-22 Lexicon Pharmaceuticals, Inc. Knockout animals manifesting hyperlipidemia
US7312079B1 (en) 2005-10-06 2007-12-25 Lexicon Pharmaceuticals, Inc. Variants of FAM3C
US20080004410A1 (en) * 2006-06-30 2008-01-03 Yu-Chin Lai Hydrophilic macromonomers having alpha,beta-conjugated carboxylic terminal group and medical devices incorporating same
WO2008056837A1 (en) * 2006-11-07 2008-05-15 Korea Research Institute Of Bioscience And Biotechnology Method for fabricating a biomaterial array using photoreaction
US20090312406A1 (en) * 2008-06-12 2009-12-17 Hsing-Pang Hsieh Coumarin compounds and their use for treating viral infection
WO2009152210A2 (en) * 2008-06-12 2009-12-17 National Health Research Institutes Coumarin compounds and their use for treating cancer
WO2014152775A2 (en) 2013-03-14 2014-09-25 Certirx Corporation Nucleic acid-based authentication and identification codes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2334107A1 (fr) * 1975-12-05 1977-07-01 Pasteur Institut Procede de couplage de substances biologiques par des liaisons covalentes
US4169204A (en) * 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
DD148955A1 (de) * 1980-02-04 1981-06-17 Hunger Hans Dieter Verfahren zur kopplung von nukleinsaeuren an traegermaterialien
CA1180647A (en) * 1981-07-17 1985-01-08 Cavit Akin Light-emitting polynucleotide hybridization diagnostic method
US4542102A (en) * 1983-07-05 1985-09-17 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4582789A (en) * 1984-03-21 1986-04-15 Cetus Corporation Process for labeling nucleic acids using psoralen derivatives

Also Published As

Publication number Publication date
JPS6036496A (ja) 1985-02-25
EP0130523A3 (en) 1986-07-23
IL72278A0 (en) 1984-11-30
AU563558B2 (en) 1987-07-16
IL72278A (en) 1989-07-31
US4713326A (en) 1987-12-15
EP0130523A2 (en) 1985-01-09
JPH075628B2 (ja) 1995-01-25
AU3025684A (en) 1985-01-10
ES8607387A1 (es) 1986-05-16
DE3471689D1 (en) 1988-07-07
EP0130523B1 (en) 1988-06-01

Similar Documents

Publication Publication Date Title
ES534025A0 (es) Un metodo de produccion de un acido nucleico inmovilizado.
ES549428A0 (es) Un procedimiento para la produccion de un acido nucleico inmovilizado y derivados del mismo.
IT1163946B (it) Metodo per la produzione di un preparato di enzima immobilizzato
KR860004802A (ko) 염소의 제조방법
DE3584981D1 (de) Verfahren zur leistungsproduktion.
ES513827A0 (es) Un metodo de produccion de un derivado de tilosina.
ES526247A0 (es) Un metodo de produccion de una preparacion de enzima inmovilizado
AR226913A1 (es) Metodo para la inmovilizacion de un microorganismo productor de enzima
DE3583636D1 (de) Herstellungsverfahren von kaliumhydroxyd.
DK359182A (da) Fremgangsmaade til fremstilling af d-maelkesyre
ES512832A0 (es) Un metodo de produccion de compuesto de dihidropiridina.
IT8123530A0 (it) Procedimento per la produzione di un derivato idrossifenilico di un acido alifatico e catalizzatore per tale procedimento.
DE3581958D1 (de) Verfahren zur herstellung von n-acetylneuraminat-lyase.
ES520929A0 (es) Un metodo de producir un organo-siloxano.
GB2128620B (en) Method for production of an immobilized enzyme preparation
MX156441A (es) Metodo mejorado para la produccion de acido fluormidrico
BR8207623A (pt) Processo para a producao de acido p-nitrotolueno-2-sulfonico
IT1186755B (it) Processo per produrre acido cinnamico
ES538075A0 (es) Un metodo de producir un fertilizante organico
ES535456A0 (es) Un metodo de preparar derivados de acido hexahidro-3,5-dioxo-1h-pirrolizino-2-carboxilico
IT8119735A0 (it) Procedimento per la produzione di acido fluoridrico.
ES499092A0 (es) Un metodo para la produccion de glucosa-isomerasa inmovili- zada
IT8121235A0 (it) Processo per la produzione di acido l-aspartico usando microorganismi immobilizzati.
ES524794A0 (es) Un metodo de produccion de l-prolina por fermentacion
BR8204069A (pt) Processo para a producao do mentilester de acido permetrinico