ES530810A0 - Un procedimiento para preparar compuestos de imidazol fusionados - Google Patents
Un procedimiento para preparar compuestos de imidazol fusionadosInfo
- Publication number
- ES530810A0 ES530810A0 ES530810A ES530810A ES530810A0 ES 530810 A0 ES530810 A0 ES 530810A0 ES 530810 A ES530810 A ES 530810A ES 530810 A ES530810 A ES 530810A ES 530810 A0 ES530810 A0 ES 530810A0
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- imidazole compounds
- fused imidazole
- preparing fused
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838307865A GB8307865D0 (en) | 1983-03-22 | 1983-03-22 | Benzimidazole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES530810A0 true ES530810A0 (es) | 1985-06-16 |
| ES8506001A1 ES8506001A1 (es) | 1985-06-16 |
Family
ID=10540007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES530810A Expired ES8506001A1 (es) | 1983-03-22 | 1984-03-21 | Un procedimiento para preparar compuestos de imidazol fusionados |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4563455A (es) |
| EP (1) | EP0125756A3 (es) |
| JP (1) | JPS59176277A (es) |
| KR (1) | KR840008016A (es) |
| AU (1) | AU2587384A (es) |
| DK (1) | DK110384A (es) |
| ES (1) | ES8506001A1 (es) |
| FI (1) | FI841082A (es) |
| GB (1) | GB8307865D0 (es) |
| GR (1) | GR79774B (es) |
| IL (1) | IL71310A0 (es) |
| NO (1) | NO841106L (es) |
| ZA (1) | ZA841393B (es) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3579436D1 (de) * | 1984-12-18 | 1990-10-04 | Otsuka Pharma Co Ltd | Tetrahydrochinolin- derivate, verfahren zu deren herstellung und diese enthaltende antimagengeschwuerzusammensetzungen. |
| US4728741A (en) * | 1985-01-08 | 1988-03-01 | Smithkline Beckman Corporation | 1-substituted-2-mercapto benzimidazole compounds and intermediates |
| DE3501497A1 (de) * | 1985-01-18 | 1986-07-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| KR950001015B1 (ko) * | 1986-01-10 | 1995-02-07 | 닛뽕 케미화 가부시끼가이샤 | 술폭시드 유도체의 제조방법 |
| US5433959A (en) * | 1986-02-13 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
| US6749864B2 (en) * | 1986-02-13 | 2004-06-15 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
| CA1327010C (en) * | 1986-02-13 | 1994-02-15 | Tadashi Makino | Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production |
| GB8612796D0 (en) * | 1986-05-27 | 1986-07-02 | Fbc Ltd | Fungicides |
| US4772600A (en) * | 1986-06-09 | 1988-09-20 | A. H. Robins Company, Inc. | Fused imidazoheterocyclic compounds and pharmaceutical compositions |
| NZ221729A (en) * | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
| DE3634066A1 (de) * | 1986-10-07 | 1988-04-21 | Boehringer Mannheim Gmbh | Neue 5-alkylbenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
| SE8604566D0 (sv) * | 1986-10-27 | 1986-10-27 | Haessle Ab | Novel compunds |
| FI91754C (fi) * | 1986-12-02 | 1994-08-10 | Tanabe Seiyaku Co | Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi |
| US5149702A (en) * | 1989-11-29 | 1992-09-22 | Toa Eiyo Ltd. | Cycloheptenopyridine derivatives, process for preparation thereof and antiulcer agents containing the same |
| US5200419A (en) * | 1990-05-21 | 1993-04-06 | Warner-Lambert Company | Substituted tetrazoles and derivatives thereof acting at muscarinic receptors |
| NO940245D0 (no) * | 1993-01-28 | 1994-01-24 | Takeda Chemical Industries Ltd | Quinolin eller quinazolinderivater, deres fremstilling og anvendelse |
| KR0156327B1 (ko) * | 1995-07-12 | 1998-11-16 | 김종인 | 벤즈 또는 피리도이미다졸 유도체 |
| SE508669C2 (sv) * | 1996-04-26 | 1998-10-26 | Astra Ab | Nytt förfarande |
| JP3256513B2 (ja) * | 1998-02-11 | 2002-02-12 | ファイザー製薬株式会社 | ベンゾイミダゾールシクロオキシゲナーゼ−２阻害剤 |
| UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| NZ535959A (en) | 2002-03-27 | 2006-05-26 | Altana Pharma Ag | Novel alkoxypyridine-derivatives as selective inhibitors of inducible nitric oxidase synthase NOS |
| BRPI0407573A (pt) | 2003-02-25 | 2006-02-14 | Altana Pharma Ag | derivados de imidazo(4,5-b)quinolina e seu emprego como inibidores de sintase de no |
| KR101179012B1 (ko) | 2003-03-10 | 2012-09-03 | 니코메드 게엠베하 | 로플루미라스트 신규한 제조 방법 |
| DE10344897A1 (de) * | 2003-09-26 | 2005-04-21 | Bosch Gmbh Robert | Ventil zur Steuerung einer Verbindung in einem Hochdruckflüssigkeitssystem, insbesondere einer Kraftstoffeinspritzeinrichtung für eine Brennkraftmaschine |
| US20080125460A1 (en) * | 2003-10-01 | 2008-05-29 | Altana Pharma Ag | Imidazopyridine-Derivatives As Inducible No-Synthase Inhibitors |
| MXPA06003351A (es) | 2003-10-01 | 2006-06-08 | Altana Pharma Ag | Derivados de imidazopiridina como inhibidores de no-sintasa inducible. |
| NZ546394A (en) * | 2003-10-01 | 2009-08-28 | Altana Pharma Ag | Aminopyridine derivatives as inductible NO-synthase inhibitors |
| US7468377B2 (en) * | 2003-10-01 | 2008-12-23 | Altana Pharma Ag | Imidazopyridine-derivatives as inductible no-synthase inhibitors |
| MXPA06003347A (es) * | 2003-10-01 | 2006-06-08 | Altana Pharma Ag | Derivados de imidazo[4,5-b]piridina como inhibidores de la no-sintasa inducible. |
| EP1861074B1 (en) * | 2005-03-16 | 2013-04-24 | Takeda GmbH | Taste masked dosage form containing roflumilast |
| PE20070335A1 (es) * | 2005-08-30 | 2007-04-21 | Novartis Ag | Benzimidazoles sustituidos y metodos para su preparacion |
| FR2949469A1 (fr) * | 2009-08-25 | 2011-03-04 | Sanofi Aventis | Derives anticancereux, leur preparation et leur application en therapeutique |
| TWI481607B (zh) | 2009-12-17 | 2015-04-21 | Lundbeck & Co As H | 作為ｐｄｅ１０ａ酵素抑制劑的２－芳基咪唑衍生物 |
| TWI487705B (zh) | 2009-12-17 | 2015-06-11 | Lundbeck & Co As H | 作為ｐｄｅ１０ａ酵素抑制劑之雜芳香族芳基三唑衍生物 |
| TWI485151B (zh) | 2009-12-17 | 2015-05-21 | Lundbeck & Co As H | 作為ｐｄｅ１０ａ酵素抑制劑之雜芳香族苯基咪唑衍生物 |
| TW201206935A (en) | 2010-07-16 | 2012-02-16 | Lundbeck & Co As H | Triazolo-and pyrazoloquinazoline derivatives as PDE10A enzyme inhibitor |
| JO3089B1 (ar) | 2010-11-19 | 2017-03-15 | H Lundbeck As | مشتقات ايميدازول كمثبطات لانزيمات pde10a |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH262959A (de) * | 1944-12-21 | 1949-07-31 | Ciba Geigy | Verfahren zur Herstellung des neuen a-(Benzthiazyl-(2))-B-(benzimidazyl-(2))-äthylens. |
| BE569485A (es) * | 1957-07-17 | |||
| FR1476560A (fr) * | 1965-08-05 | 1967-04-14 | Chimetron Sarl | Thiazolylalcoyl-2 benzimidazoles et thiadiazolylalcoyl-2 benzimidazoles alpha-halogénés ou alpha-aminés |
| FR2104717A1 (en) * | 1970-09-28 | 1972-04-21 | Dynachim Sarl | Organophosphorus pesticides stabilised with benzimidazole derivs - - for controlling insects and internal parasites of animals |
| US3897432A (en) * | 1971-04-21 | 1975-07-29 | Merck & Co Inc | Substituted benzimidazole derivatives |
| SU455104A1 (ru) * | 1971-08-11 | 1974-12-30 | Ордена Трудового Красного Знамени Институт Тонкой Органической Химии Им. А.Л.Мнджояна | Способ получени 2-метил-3-( -алкил -бензимидазолил-2")-этилиндолов |
| SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| US4294837A (en) * | 1980-03-28 | 1981-10-13 | Sterling Drug Inc. | 1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use |
| GB2101115A (en) * | 1980-10-23 | 1983-01-12 | Pfizer Ltd | Thromboxane synthetase inhibitors |
-
1983
- 1983-03-22 GB GB838307865A patent/GB8307865D0/en active Pending
-
1984
- 1984-02-24 ZA ZA841393A patent/ZA841393B/xx unknown
- 1984-02-27 DK DK110384A patent/DK110384A/da not_active Application Discontinuation
- 1984-03-09 US US06/587,981 patent/US4563455A/en not_active Expired - Fee Related
- 1984-03-12 KR KR1019840001227A patent/KR840008016A/ko not_active IP Right Cessation
- 1984-03-12 EP EP84301647A patent/EP0125756A3/en not_active Withdrawn
- 1984-03-14 GR GR74102A patent/GR79774B/el unknown
- 1984-03-19 FI FI841082A patent/FI841082A/fi not_active Application Discontinuation
- 1984-03-19 AU AU25873/84A patent/AU2587384A/en not_active Abandoned
- 1984-03-21 JP JP59054683A patent/JPS59176277A/ja active Pending
- 1984-03-21 NO NO841106A patent/NO841106L/no unknown
- 1984-03-21 ES ES530810A patent/ES8506001A1/es not_active Expired
- 1984-03-22 IL IL71310A patent/IL71310A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR840008016A (ko) | 1984-12-12 |
| EP0125756A2 (en) | 1984-11-21 |
| DK110384D0 (da) | 1984-02-27 |
| GR79774B (es) | 1984-10-31 |
| ZA841393B (en) | 1984-10-31 |
| ES8506001A1 (es) | 1985-06-16 |
| IL71310A0 (en) | 1984-06-29 |
| GB8307865D0 (en) | 1983-04-27 |
| AU2587384A (en) | 1984-09-27 |
| EP0125756A3 (en) | 1987-04-08 |
| FI841082A (fi) | 1984-09-23 |
| FI841082A0 (fi) | 1984-03-19 |
| DK110384A (da) | 1984-09-23 |
| JPS59176277A (ja) | 1984-10-05 |
| US4563455A (en) | 1986-01-07 |
| NO841106L (no) | 1984-09-24 |
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