ES506584A0 - Procedimiento para la preparacion de derivados de isoquino- leina - Google Patents
Procedimiento para la preparacion de derivados de isoquino- leinaInfo
- Publication number
- ES506584A0 ES506584A0 ES506584A ES506584A ES506584A0 ES 506584 A0 ES506584 A0 ES 506584A0 ES 506584 A ES506584 A ES 506584A ES 506584 A ES506584 A ES 506584A ES 506584 A0 ES506584 A0 ES 506584A0
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- derivatives
- leina
- isoquino
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803034001 DE3034001A1 (de) | 1980-09-10 | 1980-09-10 | Isochinolinderivate, verfahren zu ihrer hersellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES506584A0 true ES506584A0 (es) | 1983-03-01 |
ES8304563A1 ES8304563A1 (es) | 1983-03-01 |
Family
ID=6111554
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505191A Expired ES8206511A1 (es) | 1980-09-10 | 1981-09-04 | Procedimiento para la preparacion de derivados de isoquino- leina |
ES506583A Expired ES8305351A1 (es) | 1980-09-10 | 1981-10-27 | Procedimiento para la preparacion de derivados de isoquino- leina |
ES506584A Expired ES8304563A1 (es) | 1980-09-10 | 1981-10-27 | Procedimiento para la preparacion de derivados de isoquino- leina |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505191A Expired ES8206511A1 (es) | 1980-09-10 | 1981-09-04 | Procedimiento para la preparacion de derivados de isoquino- leina |
ES506583A Expired ES8305351A1 (es) | 1980-09-10 | 1981-10-27 | Procedimiento para la preparacion de derivados de isoquino- leina |
Country Status (20)
Country | Link |
---|---|
US (1) | US4590273A (es) |
EP (1) | EP0047923B1 (es) |
JP (1) | JPS5780372A (es) |
KR (1) | KR830007622A (es) |
AT (1) | ATE7389T1 (es) |
AU (1) | AU541976B2 (es) |
CA (1) | CA1168232A (es) |
DE (2) | DE3034001A1 (es) |
DK (1) | DK400681A (es) |
ES (3) | ES8206511A1 (es) |
FI (1) | FI71734C (es) |
GR (1) | GR74978B (es) |
HU (1) | HU187357B (es) |
IE (1) | IE51551B1 (es) |
IL (1) | IL63765A (es) |
NO (1) | NO813066L (es) |
NZ (1) | NZ198308A (es) |
PH (1) | PH19431A (es) |
PT (1) | PT73629B (es) |
ZA (1) | ZA816237B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4532342A (en) * | 1981-02-20 | 1985-07-30 | Warner-Lambert Company | N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
GR79603B (es) * | 1982-07-24 | 1984-10-31 | Pfizer | |
DE3244594A1 (de) * | 1982-12-02 | 1984-06-07 | Hoechst Ag, 6230 Frankfurt | 1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung |
US4544657A (en) * | 1983-05-19 | 1985-10-01 | Hoffmann-La Roche Inc. | Substituted isoquinolines |
FR2557570B1 (fr) * | 1984-01-04 | 1986-04-18 | Adir | Nouveaux derives de la quinoleine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
US4843077A (en) * | 1987-06-09 | 1989-06-27 | Ortho Pharmaceutical Corporation | Isoquinoline derivatives having renal vasodilating properties and/or cardiotonic properties and/or phosphodiesterase inhibiting properties |
US4883795A (en) * | 1988-01-22 | 1989-11-28 | Pfizer Inc. | Piperazinyl-heterocyclic compounds |
US5332733A (en) * | 1990-11-24 | 1994-07-26 | Kali-Chemie Pharma Gmbh | Heterocyclically substituted piperazinoakylbenzoxazine and piperazinoalkylbenzothiazine compounds, processes for preparing them, and medicaments containing them |
US6008352A (en) * | 1997-04-03 | 1999-12-28 | Neurogen Corporation | 1-(isoquinolin-1-yl)-4-(1-phenylmethyl) piperazines; dopamine receptor subtype specific ligands |
US5972945A (en) * | 1997-06-13 | 1999-10-26 | Neurogen Corporation | 2-aminoalkylaminoquinolines; dopamine receptor subtype specific ligands |
US6313141B1 (en) | 1997-06-13 | 2001-11-06 | Neurogen Corporation | 2-aminoalkylaminoquinolines as dopamine D4 ligands |
DE69839887D1 (de) * | 1997-10-02 | 2008-09-25 | Eisai R&D Man Co Ltd | Kondensierte pyridinderivate |
US6040448A (en) | 1997-10-24 | 2000-03-21 | Neurogen Corporation | Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands |
EP1491532B1 (en) * | 1997-10-27 | 2010-12-15 | NeuroSearch A/S | Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetyloholine receptors |
US6613901B2 (en) | 2000-03-08 | 2003-09-02 | Neurogen Corporation | 2-aminoalkylaminoquinolines as dopamine D4 ligands |
JP2009541460A (ja) * | 2006-07-03 | 2009-11-26 | ベレナギング ヴォー クリスタラク ホガー オンダーヴェイル ヴェーテンザパーリク オンダージーク エン パシェンテンゾーク | ヒスタミンh4受容体と相互作用する縮合二環式化合物 |
WO2012080284A2 (en) * | 2010-12-17 | 2012-06-21 | F. Hoffmann-La Roche Ag | Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof |
KR20190135029A (ko) | 2017-03-30 | 2019-12-05 | 에프. 호프만-라 로슈 아게 | Hpk1의 억제제인 이소퀴놀린 |
US11612606B2 (en) | 2018-10-03 | 2023-03-28 | Genentech, Inc. | 8-aminoisoquinoline compounds and uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
GB1244501A (en) * | 1968-03-09 | 1971-09-02 | Aspro Nicholas Ltd | Heterocyclic amines |
DE2030675A1 (en) * | 1969-06-23 | 1971-02-11 | Arthur D Little, Inc , Cambridge, Mass (V St A) | 3-amino-4-phenyl-isoquinoline derivs |
US3932412A (en) * | 1970-12-07 | 1976-01-13 | Sandoz, Inc. | 1-(4-Hydroxyalkylpiperazino)-isoquinoline nitrates |
DE2420012C3 (de) * | 1974-04-25 | 1980-01-10 | Dr. Karl Thomae Gmbh, 7950 Biberach | Isochinoline |
DE2503961C3 (de) * | 1975-01-31 | 1980-02-28 | Dr. Karl Thomae Gmbh, 7950 Biberach | Isochinoline |
AT342057B (de) * | 1974-04-25 | 1978-03-10 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen 3-piperazino-isochinolinen und deren salzen |
DE2811312A1 (de) * | 1978-03-16 | 1979-09-27 | Hoechst Ag | Neue isochinolinderivate, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von arzneimitteln |
DE2818403A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
DE2818423A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1980
- 1980-09-10 DE DE19803034001 patent/DE3034001A1/de not_active Withdrawn
-
1981
- 1981-09-03 DE DE8181106884T patent/DE3163510D1/de not_active Expired
- 1981-09-03 EP EP81106884A patent/EP0047923B1/de not_active Expired
- 1981-09-03 AT AT81106884T patent/ATE7389T1/de not_active IP Right Cessation
- 1981-09-04 ES ES505191A patent/ES8206511A1/es not_active Expired
- 1981-09-07 JP JP56139850A patent/JPS5780372A/ja active Pending
- 1981-09-08 KR KR1019810003356A patent/KR830007622A/ko unknown
- 1981-09-08 NZ NZ198308A patent/NZ198308A/en unknown
- 1981-09-08 GR GR65975A patent/GR74978B/el unknown
- 1981-09-08 PT PT73629A patent/PT73629B/pt unknown
- 1981-09-08 FI FI812783A patent/FI71734C/fi not_active IP Right Cessation
- 1981-09-08 IL IL63765A patent/IL63765A/xx unknown
- 1981-09-09 AU AU75091/81A patent/AU541976B2/en not_active Ceased
- 1981-09-09 IE IE2094/81A patent/IE51551B1/en unknown
- 1981-09-09 CA CA000385547A patent/CA1168232A/en not_active Expired
- 1981-09-09 HU HU812595A patent/HU187357B/hu unknown
- 1981-09-09 NO NO813066A patent/NO813066L/no unknown
- 1981-09-09 DK DK400681A patent/DK400681A/da not_active Application Discontinuation
- 1981-09-09 ZA ZA816237A patent/ZA816237B/xx unknown
- 1981-10-27 ES ES506583A patent/ES8305351A1/es not_active Expired
- 1981-10-27 ES ES506584A patent/ES8304563A1/es not_active Expired
-
1984
- 1984-02-24 PH PH30299A patent/PH19431A/en unknown
- 1984-03-28 US US06/594,366 patent/US4590273A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NZ198308A (en) | 1984-03-30 |
JPS5780372A (en) | 1982-05-19 |
AU7509181A (en) | 1982-03-18 |
US4590273A (en) | 1986-05-20 |
FI71734C (fi) | 1987-02-09 |
ES506583A0 (es) | 1983-04-01 |
NO813066L (no) | 1982-03-11 |
PT73629B (de) | 1983-04-29 |
DE3163510D1 (en) | 1984-06-14 |
IL63765A (en) | 1985-05-31 |
EP0047923A1 (de) | 1982-03-24 |
ES505191A0 (es) | 1982-08-16 |
ES8305351A1 (es) | 1983-04-01 |
AU541976B2 (en) | 1985-01-31 |
DE3034001A1 (de) | 1982-04-22 |
KR830007622A (ko) | 1983-11-04 |
GR74978B (es) | 1984-07-12 |
ATE7389T1 (de) | 1984-05-15 |
PH19431A (en) | 1986-04-15 |
IL63765A0 (en) | 1981-12-31 |
FI812783L (fi) | 1982-03-11 |
ES8206511A1 (es) | 1982-08-16 |
CA1168232A (en) | 1984-05-29 |
HU187357B (en) | 1985-12-28 |
EP0047923B1 (de) | 1984-05-09 |
IE812094L (en) | 1982-03-10 |
PT73629A (de) | 1981-10-01 |
ES8304563A1 (es) | 1983-03-01 |
DK400681A (da) | 1982-03-11 |
ZA816237B (en) | 1982-08-25 |
IE51551B1 (en) | 1987-01-07 |
FI71734B (fi) | 1986-10-31 |
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