IL63765A - Isoquinoline derivatives,a process for their preparation and pharmaceutical formulations containing them - Google Patents
Isoquinoline derivatives,a process for their preparation and pharmaceutical formulations containing themInfo
- Publication number
- IL63765A IL63765A IL63765A IL6376581A IL63765A IL 63765 A IL63765 A IL 63765A IL 63765 A IL63765 A IL 63765A IL 6376581 A IL6376581 A IL 6376581A IL 63765 A IL63765 A IL 63765A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- isoquinoline derivatives
- pharmaceutical formulations
- formulations containing
- antihypertonic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19803034001 DE3034001A1 (de) | 1980-09-10 | 1980-09-10 | Isochinolinderivate, verfahren zu ihrer hersellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL63765A0 IL63765A0 (en) | 1981-12-31 |
IL63765A true IL63765A (en) | 1985-05-31 |
Family
ID=6111554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL63765A IL63765A (en) | 1980-09-10 | 1981-09-08 | Isoquinoline derivatives,a process for their preparation and pharmaceutical formulations containing them |
Country Status (20)
Country | Link |
---|---|
US (1) | US4590273A (xx) |
EP (1) | EP0047923B1 (xx) |
JP (1) | JPS5780372A (xx) |
KR (1) | KR830007622A (xx) |
AT (1) | ATE7389T1 (xx) |
AU (1) | AU541976B2 (xx) |
CA (1) | CA1168232A (xx) |
DE (2) | DE3034001A1 (xx) |
DK (1) | DK400681A (xx) |
ES (3) | ES8206511A1 (xx) |
FI (1) | FI71734C (xx) |
GR (1) | GR74978B (xx) |
HU (1) | HU187357B (xx) |
IE (1) | IE51551B1 (xx) |
IL (1) | IL63765A (xx) |
NO (1) | NO813066L (xx) |
NZ (1) | NZ198308A (xx) |
PH (1) | PH19431A (xx) |
PT (1) | PT73629B (xx) |
ZA (1) | ZA816237B (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4532342A (en) * | 1981-02-20 | 1985-07-30 | Warner-Lambert Company | N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
GR79603B (xx) * | 1982-07-24 | 1984-10-31 | Pfizer | |
DE3244594A1 (de) * | 1982-12-02 | 1984-06-07 | Hoechst Ag, 6230 Frankfurt | 1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung |
US4544657A (en) * | 1983-05-19 | 1985-10-01 | Hoffmann-La Roche Inc. | Substituted isoquinolines |
FR2557570B1 (fr) * | 1984-01-04 | 1986-04-18 | Adir | Nouveaux derives de la quinoleine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
US4843077A (en) * | 1987-06-09 | 1989-06-27 | Ortho Pharmaceutical Corporation | Isoquinoline derivatives having renal vasodilating properties and/or cardiotonic properties and/or phosphodiesterase inhibiting properties |
US4883795A (en) * | 1988-01-22 | 1989-11-28 | Pfizer Inc. | Piperazinyl-heterocyclic compounds |
US5332733A (en) * | 1990-11-24 | 1994-07-26 | Kali-Chemie Pharma Gmbh | Heterocyclically substituted piperazinoakylbenzoxazine and piperazinoalkylbenzothiazine compounds, processes for preparing them, and medicaments containing them |
US6008352A (en) * | 1997-04-03 | 1999-12-28 | Neurogen Corporation | 1-(isoquinolin-1-yl)-4-(1-phenylmethyl) piperazines; dopamine receptor subtype specific ligands |
US5972945A (en) * | 1997-06-13 | 1999-10-26 | Neurogen Corporation | 2-aminoalkylaminoquinolines; dopamine receptor subtype specific ligands |
US6313141B1 (en) | 1997-06-13 | 2001-11-06 | Neurogen Corporation | 2-aminoalkylaminoquinolines as dopamine D4 ligands |
US6340759B1 (en) | 1997-10-02 | 2002-01-22 | Eisai Co., Ltd. | Fused pyridine derivatives |
US6040448A (en) | 1997-10-24 | 2000-03-21 | Neurogen Corporation | Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands |
DE69826883T2 (de) * | 1997-10-27 | 2005-02-03 | Neurosearch A/S | Heteroaryl diazacycloalkane als cholinergische ligande für nikotin-acetylcholin-rezeptoren |
US6613901B2 (en) | 2000-03-08 | 2003-09-02 | Neurogen Corporation | 2-aminoalkylaminoquinolines as dopamine D4 ligands |
AU2007271187A1 (en) * | 2006-07-03 | 2008-01-10 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg | Fused bicyclic compounds interacting with the histamine H4 receptor |
MA34836B1 (fr) * | 2010-12-17 | 2014-01-02 | Hoffmann La Roche | Composes heterocycliques azotes 6;6- condenses substitues et leurs utilisations |
CN110709392B (zh) | 2017-03-30 | 2023-09-29 | 豪夫迈·罗氏有限公司 | 作为hpk1抑制剂的异喹啉 |
US11612606B2 (en) | 2018-10-03 | 2023-03-28 | Genentech, Inc. | 8-aminoisoquinoline compounds and uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
GB1244501A (en) * | 1968-03-09 | 1971-09-02 | Aspro Nicholas Ltd | Heterocyclic amines |
DE2030675A1 (en) * | 1969-06-23 | 1971-02-11 | Arthur D Little, Inc , Cambridge, Mass (V St A) | 3-amino-4-phenyl-isoquinoline derivs |
US3932412A (en) * | 1970-12-07 | 1976-01-13 | Sandoz, Inc. | 1-(4-Hydroxyalkylpiperazino)-isoquinoline nitrates |
DE2503961C3 (de) * | 1975-01-31 | 1980-02-28 | Dr. Karl Thomae Gmbh, 7950 Biberach | Isochinoline |
DE2420012C3 (de) * | 1974-04-25 | 1980-01-10 | Dr. Karl Thomae Gmbh, 7950 Biberach | Isochinoline |
AT342057B (de) * | 1974-04-25 | 1978-03-10 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen 3-piperazino-isochinolinen und deren salzen |
DE2811312A1 (de) * | 1978-03-16 | 1979-09-27 | Hoechst Ag | Neue isochinolinderivate, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von arzneimitteln |
DE2818423A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
DE2818403A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1980
- 1980-09-10 DE DE19803034001 patent/DE3034001A1/de not_active Withdrawn
-
1981
- 1981-09-03 DE DE8181106884T patent/DE3163510D1/de not_active Expired
- 1981-09-03 EP EP81106884A patent/EP0047923B1/de not_active Expired
- 1981-09-03 AT AT81106884T patent/ATE7389T1/de not_active IP Right Cessation
- 1981-09-04 ES ES505191A patent/ES8206511A1/es not_active Expired
- 1981-09-07 JP JP56139850A patent/JPS5780372A/ja active Pending
- 1981-09-08 PT PT73629A patent/PT73629B/pt unknown
- 1981-09-08 KR KR1019810003356A patent/KR830007622A/ko unknown
- 1981-09-08 GR GR65975A patent/GR74978B/el unknown
- 1981-09-08 IL IL63765A patent/IL63765A/xx unknown
- 1981-09-08 FI FI812783A patent/FI71734C/fi not_active IP Right Cessation
- 1981-09-08 NZ NZ198308A patent/NZ198308A/en unknown
- 1981-09-09 NO NO813066A patent/NO813066L/no unknown
- 1981-09-09 DK DK400681A patent/DK400681A/da not_active Application Discontinuation
- 1981-09-09 IE IE2094/81A patent/IE51551B1/en unknown
- 1981-09-09 ZA ZA816237A patent/ZA816237B/xx unknown
- 1981-09-09 AU AU75091/81A patent/AU541976B2/en not_active Ceased
- 1981-09-09 HU HU812595A patent/HU187357B/hu unknown
- 1981-09-09 CA CA000385547A patent/CA1168232A/en not_active Expired
- 1981-10-27 ES ES506584A patent/ES8304563A1/es not_active Expired
- 1981-10-27 ES ES506583A patent/ES506583A0/es active Granted
-
1984
- 1984-02-24 PH PH30299A patent/PH19431A/en unknown
- 1984-03-28 US US06/594,366 patent/US4590273A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ZA816237B (en) | 1982-08-25 |
FI71734B (fi) | 1986-10-31 |
HU187357B (en) | 1985-12-28 |
KR830007622A (ko) | 1983-11-04 |
DK400681A (da) | 1982-03-11 |
CA1168232A (en) | 1984-05-29 |
FI812783L (fi) | 1982-03-11 |
IL63765A0 (en) | 1981-12-31 |
ATE7389T1 (de) | 1984-05-15 |
ES8305351A1 (es) | 1983-04-01 |
ES505191A0 (es) | 1982-08-16 |
ES506583A0 (es) | 1983-04-01 |
PT73629B (de) | 1983-04-29 |
DE3163510D1 (en) | 1984-06-14 |
AU541976B2 (en) | 1985-01-31 |
NZ198308A (en) | 1984-03-30 |
PH19431A (en) | 1986-04-15 |
ES506584A0 (es) | 1983-03-01 |
NO813066L (no) | 1982-03-11 |
IE51551B1 (en) | 1987-01-07 |
US4590273A (en) | 1986-05-20 |
ES8304563A1 (es) | 1983-03-01 |
AU7509181A (en) | 1982-03-18 |
EP0047923B1 (de) | 1984-05-09 |
PT73629A (de) | 1981-10-01 |
FI71734C (fi) | 1987-02-09 |
JPS5780372A (en) | 1982-05-19 |
DE3034001A1 (de) | 1982-04-22 |
GR74978B (xx) | 1984-07-12 |
EP0047923A1 (de) | 1982-03-24 |
ES8206511A1 (es) | 1982-08-16 |
IE812094L (en) | 1982-03-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL63765A (en) | Isoquinoline derivatives,a process for their preparation and pharmaceutical formulations containing them | |
ZA863382B (en) | Quinolylglycinamide derivatives,the process for preparation thereof and their therapeutic application as psychotropic drugs | |
ES8305684A1 (es) | Procedimiento para la obtencion de derivados aminopropanolicos de 2-hidroxi b-fenil-propiofenonas. | |
SE8302554D0 (sv) | New azepinoindoles, their production and pharmaceutical compositions containing them | |
DE3369983D1 (en) | Isoquinoline derivatives, process for their preparation, pharmaceutical compositions containing them and their use | |
PH19471A (en) | Oxindole derivatives and pharmaceutical composition containing them | |
ES8304122A1 (es) | "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos". | |
ZA891234B (en) | 6-oxo-pyridazine derivatives,a process for their preparation and medicaments containing these compounds | |
DE3378120D1 (en) | Thiazaspiro derivatives, process for their preparation and pharmaceutical composition | |
IE873212L (en) | Medicaments based on derivatives of 3,4-di-phenylpiperidine,¹the use of the derivatives as medicaments, and novel¹3,4-diphenylpiperidine derivatives and a process for the¹preparation therefor | |
ES8705888A1 (es) | Procedimiento para preparar compuetos de imidazo-isoquino-leina y de imidazo-tienopiridina |