ES486298A1 - Un procedimiento para la preparacion de 2-metil-3-(b-hidro- ximetilcarbamoil)quinoxalina 1,4-di-n-oxido de gran pureza - Google Patents

Un procedimiento para la preparacion de 2-metil-3-(b-hidro- ximetilcarbamoil)quinoxalina 1,4-di-n-oxido de gran pureza

Info

Publication number
ES486298A1
ES486298A1 ES486298A ES486298A ES486298A1 ES 486298 A1 ES486298 A1 ES 486298A1 ES 486298 A ES486298 A ES 486298A ES 486298 A ES486298 A ES 486298A ES 486298 A1 ES486298 A1 ES 486298A1
Authority
ES
Spain
Prior art keywords
quinoxaline
methyl
oxide
hydroxyethylcarbamoyl
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486298A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marxer SpA
Original Assignee
Marxer SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marxer SpA filed Critical Marxer SpA
Publication of ES486298A1 publication Critical patent/ES486298A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Un procedimiento para la preparación de 2-metil-3- (beta-hidroximetilcarbamoil) quinoxalina 1, 4-di- N-oxido de gran pureza, que comprende las siguientes etapas realizadas separadas y sucesivamente. a)reacción de benzofuroxano con un ester del acido acetoacetico de formula CH3-CO- CH2-COOR en presencia de un catalizador en forma de etanolamina y en un disolvente adecuado; b)separacion y aislamiento del producto de reaccion formado en a), es decir 2-metil-3- (metilcaboxilato)-quinoxalina-1,4-di-N-oxido; c) reacción del compuesto descrito en b) con un exceso de etanolamina con respecto a la cantidad estequiometrica para dar el carbamoil derivado final.
ES486298A 1978-11-24 1979-11-23 Un procedimiento para la preparacion de 2-metil-3-(b-hidro- ximetilcarbamoil)quinoxalina 1,4-di-n-oxido de gran pureza Expired ES486298A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT7869686A IT7869686A0 (it) 1978-11-24 1978-11-24 Procedimento di preparazione di 2metil 3 bidrossietilcarbamollchinossalina i.4 di n ossido puroed altri composti ad esso simili

Publications (1)

Publication Number Publication Date
ES486298A1 true ES486298A1 (es) 1980-09-16

Family

ID=11312625

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486298A Expired ES486298A1 (es) 1978-11-24 1979-11-23 Un procedimiento para la preparacion de 2-metil-3-(b-hidro- ximetilcarbamoil)quinoxalina 1,4-di-n-oxido de gran pureza

Country Status (5)

Country Link
US (1) US4228283A (es)
JP (1) JPS5573663A (es)
DE (1) DE2907174A1 (es)
ES (1) ES486298A1 (es)
IT (1) IT7869686A0 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT379805B (de) * 1981-11-06 1986-03-10 Ind Quimica Agropecuaria S A Verfahren zur herstellung einer chinoxalinverbindung
JPS60252413A (ja) * 1984-05-28 1985-12-13 Touri:Kk 水産動物の疾病の予防、治療剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670693C3 (de) * 1966-05-04 1975-10-16 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Chinoxalin-di-N-oxiden
GB1134729A (en) * 1966-11-08 1968-11-27 Research Corp Quinoxaline-di-n-oxides
DE1670935C3 (de) * 1967-10-04 1975-12-04 Bayer Ag, 5090 Leverkusen 2-Methyl-3-carbonsäureamidochinoxalin-1,4-dl-N-oxide, ein Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende antibakterielle Mittel
DE1770975A1 (de) * 1968-07-25 1972-01-13 Hoechst Ag Bakteriostatisch wirksame Chinoxalin-1,4-dioxyde
DE1813918C3 (de) * 1968-12-11 1979-02-15 Bayer Ag 2-Hydroxymethyl-3-carbonsäureamido--chinoxalin-M-di-N-oxide, ein Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende antibakterielle Mittel
GB1325581A (en) * 1969-07-22 1973-08-01 Pfizer 3-methyl-2-quinoxalinecarboxamide-di-n-oxides
GB1308370A (en) 1969-12-09 1973-02-21 Research Corp 1-hydroxy-3-oxo-benzimidazoles quinoxaline-di-n-oxides and benzimidazole-mono-and di-n-oxides
BE787116A (fr) * 1971-08-06 1973-02-05 Pfizer Transesterification d'esters d'acides quinoxaline-2- carboxyliques
DE2304536A1 (de) * 1973-01-31 1974-08-01 Bayer Ag 2-hydroxy-3-cyano-chinoxalin-di-noxide
US4039540A (en) * 1974-05-07 1977-08-02 Pfizer Inc. 3-Substituted quinoxaline-2-carboxamide-1,4-dioxides
US3948911A (en) * 1974-11-19 1976-04-06 Pfizer Inc. Substituted quinoxaline-2-carboxamide 1,4-dioxides
SU890961A3 (ru) * 1976-01-20 1981-12-15 Циба-Гейги Аг (Фирма) Ростстимулирующее средство дл животных

Also Published As

Publication number Publication date
DE2907174A1 (de) 1980-05-29
JPS5573663A (en) 1980-06-03
IT7869686A0 (it) 1978-11-24
US4228283A (en) 1980-10-14

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