ATE24322T1 - Verfahren und zwischenprodukte zur herstellung des 1,1-dioxopenicillanoylmethylesters der 6-beta-aminopenicillansaeure. - Google Patents

Verfahren und zwischenprodukte zur herstellung des 1,1-dioxopenicillanoylmethylesters der 6-beta-aminopenicillansaeure.

Info

Publication number
ATE24322T1
ATE24322T1 AT83306460T AT83306460T ATE24322T1 AT E24322 T1 ATE24322 T1 AT E24322T1 AT 83306460 T AT83306460 T AT 83306460T AT 83306460 T AT83306460 T AT 83306460T AT E24322 T1 ATE24322 T1 AT E24322T1
Authority
AT
Austria
Prior art keywords
beta
preparation
dioxopenicillanoylmethyl
aminopenicillan
ester
Prior art date
Application number
AT83306460T
Other languages
English (en)
Inventor
Paul D Weeks
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE24322T1 publication Critical patent/ATE24322T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
    • C07D499/32—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cultivation Of Plants (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT83306460T 1982-11-01 1983-10-25 Verfahren und zwischenprodukte zur herstellung des 1,1-dioxopenicillanoylmethylesters der 6-beta-aminopenicillansaeure. ATE24322T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/438,228 US4530792A (en) 1982-11-01 1982-11-01 Process and intermediates for preparation of 1,1-dioxopenicillanoyloxymethyl 6-beta-aminopenicillanate
EP83306460A EP0108545B1 (de) 1982-11-01 1983-10-25 Verfahren und Zwischenprodukte zur Herstellung des 1,1-Dioxopenicillanoylmethylesters der 6-Beta-Aminopenicillansäure

Publications (1)

Publication Number Publication Date
ATE24322T1 true ATE24322T1 (de) 1987-01-15

Family

ID=23739781

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83306460T ATE24322T1 (de) 1982-11-01 1983-10-25 Verfahren und zwischenprodukte zur herstellung des 1,1-dioxopenicillanoylmethylesters der 6-beta-aminopenicillansaeure.

Country Status (25)

Country Link
US (1) US4530792A (de)
EP (1) EP0108545B1 (de)
JP (1) JPS5998090A (de)
KR (1) KR860001494B1 (de)
AT (1) ATE24322T1 (de)
AU (1) AU541962B2 (de)
CA (1) CA1204736A (de)
CS (1) CS235986B2 (de)
DD (1) DD213926A5 (de)
DE (1) DE3368417D1 (de)
DK (1) DK163515C (de)
EG (1) EG15987A (de)
ES (1) ES8602014A1 (de)
FI (1) FI76576C (de)
GR (1) GR78943B (de)
GT (1) GT198303898A (de)
HU (1) HU189769B (de)
IE (1) IE56179B1 (de)
IL (1) IL70095A (de)
NZ (1) NZ206108A (de)
PH (1) PH19573A (de)
PL (1) PL142735B1 (de)
PT (1) PT77580B (de)
YU (1) YU43989B (de)
ZA (1) ZA838091B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01139584A (ja) * 1987-11-25 1989-06-01 Yoshitomi Pharmaceut Ind Ltd ペニシラン酸化合物の製造法
GB2231049A (en) * 1989-04-14 1990-11-07 Yoshitomi Pharmaceutical Method for producing diester compounds
DE69103003T2 (de) * 1990-04-13 1994-11-03 Pfizer Inc., Groton, Conn. Verfahren für sultamicillinzwischenprodukt.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896110A (en) * 1971-10-04 1975-07-22 American Home Prod Process for preparation of 6-aminopenicillanic acid
GB1382736A (en) * 1971-11-16 1975-02-05 Yamanouchi Pharma Co Ltd Process of producing semi-synthetic penicillin
FR2275460A1 (fr) * 1974-06-20 1976-01-16 Schmoller & Bompard Procede pour la preparation de l'acide 6-aminopenicillanique
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IE49881B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4364957A (en) * 1979-09-26 1982-12-21 Pfizer Inc. Bis-esters of alkanediols as antibacterial agents
US4376076A (en) * 1981-03-23 1983-03-08 Pfizer Inc. Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents
US4375434A (en) * 1982-06-21 1983-03-01 Pfizer Inc. Process for 6'-amino-penicillanoyloxymethyl penicillanate 1,1-dioxide

Also Published As

Publication number Publication date
US4530792A (en) 1985-07-23
CA1204736A (en) 1986-05-20
HU189769B (en) 1986-07-28
FI833961A0 (fi) 1983-10-28
YU43989B (en) 1990-02-28
YU216283A (en) 1986-02-28
FI833961A (fi) 1984-05-02
IE832539L (en) 1984-05-01
DK497483D0 (da) 1983-10-31
PT77580A (en) 1983-11-01
NZ206108A (en) 1986-06-11
GT198303898A (es) 1985-04-20
EP0108545A1 (de) 1984-05-16
EG15987A (en) 1989-03-30
DD213926A5 (de) 1984-09-26
FI76576C (fi) 1988-11-10
AU2082183A (en) 1984-05-10
KR840007009A (ko) 1984-12-04
ZA838091B (en) 1985-06-26
PL142735B1 (en) 1987-11-30
PT77580B (en) 1986-05-27
IE56179B1 (en) 1991-05-08
DK497483A (da) 1984-05-02
CS235986B2 (en) 1985-05-15
JPS5998090A (ja) 1984-06-06
IL70095A (en) 1988-03-31
IL70095A0 (en) 1984-01-31
AU541962B2 (en) 1985-01-31
EP0108545B1 (de) 1986-12-17
DK163515B (da) 1992-03-09
GR78943B (de) 1984-10-02
DE3368417D1 (en) 1987-01-29
JPH0329796B2 (de) 1991-04-25
KR860001494B1 (ko) 1986-09-27
FI76576B (fi) 1988-07-29
ES526942A0 (es) 1985-11-01
DK163515C (da) 1992-08-24
PL244352A1 (en) 1985-02-27
ES8602014A1 (es) 1985-11-01
PH19573A (en) 1986-05-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time