ES466794A1 - Un procedimiento para la preparacion de derivados de imida- zol. - Google Patents
Un procedimiento para la preparacion de derivados de imida- zol.Info
- Publication number
- ES466794A1 ES466794A1 ES466794A ES466794A ES466794A1 ES 466794 A1 ES466794 A1 ES 466794A1 ES 466794 A ES466794 A ES 466794A ES 466794 A ES466794 A ES 466794A ES 466794 A1 ES466794 A1 ES 466794A1
- Authority
- ES
- Spain
- Prior art keywords
- dicyclic
- sulphones
- antiinflammatory
- imidazoles
- substituted thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76722077A | 1977-02-09 | 1977-02-09 | |
| US05/865,832 US4159338A (en) | 1977-02-09 | 1978-01-05 | Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466794A1 true ES466794A1 (es) | 1979-08-01 |
Family
ID=27117879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466794A Expired ES466794A1 (es) | 1977-02-09 | 1978-02-08 | Un procedimiento para la preparacion de derivados de imida- zol. |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS53130664A (fi) |
| AR (1) | AR219310A1 (fi) |
| AT (1) | AT361470B (fi) |
| AU (1) | AU517028B2 (fi) |
| CA (1) | CA1105024A (fi) |
| CH (1) | CH644108A5 (fi) |
| DE (1) | DE2805167A1 (fi) |
| DK (1) | DK16778A (fi) |
| ES (1) | ES466794A1 (fi) |
| FI (1) | FI69462C (fi) |
| FR (1) | FR2380275A1 (fi) |
| GB (1) | GB1564184A (fi) |
| GR (1) | GR64142B (fi) |
| HU (1) | HU178211B (fi) |
| IE (1) | IE46187B1 (fi) |
| IL (1) | IL53995A (fi) |
| IT (1) | IT1092588B (fi) |
| LU (1) | LU79024A1 (fi) |
| MX (1) | MX5933E (fi) |
| NL (1) | NL7801453A (fi) |
| NO (1) | NO148265C (fi) |
| NZ (1) | NZ186410A (fi) |
| PH (1) | PH13852A (fi) |
| PT (1) | PT67626B (fi) |
| SE (1) | SE7801467L (fi) |
| YU (1) | YU28878A (fi) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2963572D1 (en) * | 1978-04-11 | 1982-10-21 | Ciba Geigy Ag | Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions |
| US4199592A (en) * | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
| DK337779A (da) * | 1978-10-02 | 1980-04-03 | Du Pont | Fremgangsmaade til fremstilling af antiinflammatoriske 2-substituerede 1h-phenantro (9,10)-imidazoler |
| AT374198B (de) * | 1979-04-10 | 1984-03-26 | Ciba Geigy Ag | Verfahren zur herstellung neuer 2-substituierter mercaptoimidazolderivate, ihrer n-oxyde und ihrer salze |
| FI850995L (fi) * | 1984-03-16 | 1985-09-17 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya 3-merkapto-1,2,4-triazacykloalkadienderivat. |
| US6040320A (en) * | 1997-06-30 | 2000-03-21 | Ortho-Mcneil Pharmaceutical, Inc. | 2-substituted imidazoles useful in the treatment of inflammatory diseases |
| DE10107683A1 (de) | 2001-02-19 | 2002-08-29 | Merckle Gmbh Chem Pharm Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2981739A (en) * | 1958-01-27 | 1961-04-25 | Diamond Alkali Co | Certain alpha-haloaldehyde addition products of ethylenethioureas and process |
| US3714179A (en) * | 1970-09-08 | 1973-01-30 | Searle & Co | 1-alkyl-2-furfurylthioimidazoles and congeners |
| JPS5343958B2 (fi) * | 1972-07-29 | 1978-11-24 | ||
| SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
-
1978
- 1978-01-13 DK DK16778A patent/DK16778A/da not_active Application Discontinuation
- 1978-02-06 PT PT67626A patent/PT67626B/pt unknown
- 1978-02-07 IT IT7820078A patent/IT1092588B/it active
- 1978-02-07 CA CA296,606A patent/CA1105024A/en not_active Expired
- 1978-02-08 GB GB5098/78A patent/GB1564184A/en not_active Expired
- 1978-02-08 DE DE19782805167 patent/DE2805167A1/de not_active Withdrawn
- 1978-02-08 SE SE7801467A patent/SE7801467L/xx unknown
- 1978-02-08 AU AU33096/78A patent/AU517028B2/en not_active Expired
- 1978-02-08 FR FR7803518A patent/FR2380275A1/fr active Granted
- 1978-02-08 NO NO780433A patent/NO148265C/no unknown
- 1978-02-08 ES ES466794A patent/ES466794A1/es not_active Expired
- 1978-02-08 AT AT86978A patent/AT361470B/de not_active IP Right Cessation
- 1978-02-08 NZ NZ186410A patent/NZ186410A/xx unknown
- 1978-02-08 LU LU79024A patent/LU79024A1/xx unknown
- 1978-02-08 MX MX786829U patent/MX5933E/es unknown
- 1978-02-08 IE IE279/78A patent/IE46187B1/en unknown
- 1978-02-08 IL IL53995A patent/IL53995A/xx unknown
- 1978-02-08 NL NL7801453A patent/NL7801453A/xx not_active Application Discontinuation
- 1978-02-08 YU YU00288/78A patent/YU28878A/xx unknown
- 1978-02-09 GR GR55396A patent/GR64142B/el unknown
- 1978-02-09 HU HU78DU279A patent/HU178211B/hu unknown
- 1978-02-09 AR AR271048A patent/AR219310A1/es active
- 1978-02-09 CH CH147478A patent/CH644108A5/de not_active IP Right Cessation
- 1978-02-09 JP JP1304678A patent/JPS53130664A/ja active Pending
- 1978-02-09 PH PH20771A patent/PH13852A/en unknown
- 1978-02-09 FI FI780428A patent/FI69462C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS53130664A (en) | 1978-11-14 |
| MX5933E (es) | 1984-08-30 |
| AU3309678A (en) | 1979-08-16 |
| PH13852A (en) | 1980-10-22 |
| FR2380275B1 (fi) | 1982-01-08 |
| IE780279L (en) | 1978-08-09 |
| HU178211B (en) | 1982-03-28 |
| YU28878A (en) | 1983-01-21 |
| FR2380275A1 (fr) | 1978-09-08 |
| GB1564184A (en) | 1980-04-02 |
| NO148265C (no) | 1983-09-07 |
| CH644108A5 (en) | 1984-07-13 |
| AT361470B (de) | 1981-03-10 |
| FI69462B (fi) | 1985-10-31 |
| PT67626B (en) | 1979-07-17 |
| ATA86978A (de) | 1980-08-15 |
| NZ186410A (en) | 1979-12-11 |
| FI780428A (fi) | 1978-08-10 |
| NO780433L (no) | 1978-08-10 |
| IT7820078A0 (it) | 1978-02-07 |
| IT1092588B (it) | 1985-07-12 |
| CA1105024A (en) | 1981-07-14 |
| AU517028B2 (en) | 1981-07-02 |
| IL53995A (en) | 1982-02-28 |
| LU79024A1 (fr) | 1979-05-25 |
| IL53995A0 (en) | 1978-04-30 |
| AR219310A1 (es) | 1980-08-15 |
| DE2805167A1 (de) | 1978-08-10 |
| NO148265B (no) | 1983-05-30 |
| IE46187B1 (en) | 1983-03-23 |
| SE7801467L (sv) | 1978-08-10 |
| GR64142B (en) | 1980-01-28 |
| PT67626A (en) | 1978-03-01 |
| DK16778A (da) | 1978-08-10 |
| FI69462C (fi) | 1986-02-10 |
| NL7801453A (nl) | 1978-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |