ES474746A1 - Ÿun procedimiento de preparacion de derivados de la eburna- meninaŸ - Google Patents

Ÿun procedimiento de preparacion de derivados de la eburna- meninaŸ

Info

Publication number
ES474746A1
ES474746A1 ES474746A ES474746A ES474746A1 ES 474746 A1 ES474746 A1 ES 474746A1 ES 474746 A ES474746 A ES 474746A ES 474746 A ES474746 A ES 474746A ES 474746 A1 ES474746 A1 ES 474746A1
Authority
ES
Spain
Prior art keywords
eburnamenine
derivatives
preparation
cycloalkyl
therapeutical application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES474746A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES474746A1 publication Critical patent/ES474746A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un procedimiento de preparación de derivados de la eburnamenina, en la forma de epímeros en C14 y en la forma de racémicos o de enantiómeros, que responden a la fórmula **(Fórmula)** en la cual: cuando R1 representa H y R2 representa OH o cuando R1 y R2 representan juntos un doble enlace, R3 representa un grupo COOR4 ó CONR5R6 en los cuales R4 es un alcohilo de 2 a 6 átomos de carbono o un cicloalcohilo de 3 a 6 átomos de carbono y R5 y R6 son independientemente uno del otro un átomo de hidrógeno, un alcohilo de 12 a 6 átomos de carbono o un cicloalcohilo de 3 a 6 átomos de carbono ó NR5R6 forman juntos un radical heterocíclicos que puede llevar o no otro heteroátomo.
ES474746A 1977-11-02 1978-11-02 Ÿun procedimiento de preparacion de derivados de la eburna- meninaŸ Expired ES474746A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7732855A FR2407931A1 (fr) 1977-11-02 1977-11-02 Derives de l'eburnamenine et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES474746A1 true ES474746A1 (es) 1979-03-16

Family

ID=9197135

Family Applications (1)

Application Number Title Priority Date Filing Date
ES474746A Expired ES474746A1 (es) 1977-11-02 1978-11-02 Ÿun procedimiento de preparacion de derivados de la eburna- meninaŸ

Country Status (11)

Country Link
EP (1) EP0001940A1 (es)
JP (1) JPS5473800A (es)
AT (1) ATA783078A (es)
AU (1) AU4129978A (es)
ES (1) ES474746A1 (es)
FR (1) FR2407931A1 (es)
GR (1) GR65011B (es)
IL (1) IL55931A0 (es)
IT (1) IT1101269B (es)
PT (1) PT68737A (es)
ZA (1) ZA786161B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180929B (en) * 1979-08-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing new bromo-vincamone derivatives
HU181939B (en) * 1979-10-15 1983-11-28 Richter Gedeon Vegyeszet Process for preparing halogeno-apovincaminic acid ester derivatives
DK2513324T3 (en) 2009-12-17 2016-11-07 Wintershall Holding GmbH PROCEDURE FOR THE PREPARATION OF HOMOPOLYSACCHARIDES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK139358B (da) * 1973-12-18 1979-02-05 Sandoz Ag Analogifremgangsmåde til fremstilling af vincaminderivater eller syreadditionssalte deraf.
FR2275211A2 (fr) * 1974-06-19 1976-01-16 Synthelabo Nouveaux amides de l'acide dihydroapovincaminique, leurs sels, leur preparation et les medicaments qui en contiennent
FI751840A (es) * 1974-09-24 1976-03-25 Synthelabo

Also Published As

Publication number Publication date
FR2407931B1 (es) 1980-08-08
ZA786161B (en) 1979-10-31
PT68737A (fr) 1978-12-01
IT7829384A0 (it) 1978-11-02
GR65011B (en) 1980-06-12
FR2407931A1 (fr) 1979-06-01
JPS5473800A (en) 1979-06-13
IL55931A0 (en) 1979-01-31
IT1101269B (it) 1985-09-28
EP0001940A1 (fr) 1979-05-16
AU4129978A (en) 1979-05-17
ATA783078A (de) 1980-07-15

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