ES466493A1 - Procedimiento de fabricacion de acidos a-aril-a -oxo-isovalericos. - Google Patents
Procedimiento de fabricacion de acidos a-aril-a -oxo-isovalericos.Info
- Publication number
- ES466493A1 ES466493A1 ES466493A ES466493A ES466493A1 ES 466493 A1 ES466493 A1 ES 466493A1 ES 466493 A ES466493 A ES 466493A ES 466493 A ES466493 A ES 466493A ES 466493 A1 ES466493 A1 ES 466493A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- phenylbutyric acid
- pharmaceutical compostions
- compostions containing
- dervatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OBKXEAXTFZPCHS-UHFFFAOYSA-N 4-phenylbutyric acid Chemical compound OC(=O)CCCC1=CC=CC=C1 OBKXEAXTFZPCHS-UHFFFAOYSA-N 0.000 title 2
- 229950009215 phenylbutanoic acid Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7702959A FR2378741A1 (fr) | 1977-02-01 | 1977-02-01 | Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques |
Publications (1)
Publication Number | Publication Date |
---|---|
ES466493A1 true ES466493A1 (es) | 1979-05-01 |
Family
ID=9186227
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES466493A Expired ES466493A1 (es) | 1977-02-01 | 1978-01-31 | Procedimiento de fabricacion de acidos a-aril-a -oxo-isovalericos. |
Country Status (8)
Country | Link |
---|---|
BE (1) | BE863196A (en, 2012) |
CA (1) | CA1097684A (en, 2012) |
CH (1) | CH628014A5 (en, 2012) |
DE (1) | DE2804293A1 (en, 2012) |
ES (1) | ES466493A1 (en, 2012) |
FR (1) | FR2378741A1 (en, 2012) |
GB (1) | GB1565616A (en, 2012) |
NL (1) | NL7801057A (en, 2012) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS243570B1 (en) * | 1984-08-31 | 1986-06-12 | Miroslav Kuchar | Omega-aryloxoalkane acids |
US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
AR002945A1 (es) * | 1994-11-15 | 1998-05-27 | Bayer Corp | Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos |
US5886022A (en) * | 1995-06-05 | 1999-03-23 | Bayer Corporation | Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors |
GB9522615D0 (en) * | 1995-11-03 | 1996-01-03 | Pharmacia Spa | 4-Phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity |
US5863915A (en) * | 1996-05-15 | 1999-01-26 | Bayer Corporation | Substituted 4-arylbutyric acid derivatives as matrix metalloprotease |
HRP970245B1 (en) | 1996-05-15 | 2002-06-30 | Bayer Ag | Biaryl acetilenes as matrix metalloprotease inhibitors |
TNSN97086A1 (fr) * | 1996-05-15 | 2005-03-15 | Bayer Corp | La substitution des acides derivatives 4-albutyrique comme inhibiteurs de la matrice metalloprotease. |
-
1977
- 1977-02-01 FR FR7702959A patent/FR2378741A1/fr active Granted
-
1978
- 1978-01-23 BE BE184536A patent/BE863196A/xx not_active IP Right Cessation
- 1978-01-30 NL NL7801057A patent/NL7801057A/xx not_active Application Discontinuation
- 1978-01-30 CA CA295,903A patent/CA1097684A/fr not_active Expired
- 1978-01-31 ES ES466493A patent/ES466493A1/es not_active Expired
- 1978-02-01 CH CH110878A patent/CH628014A5/fr not_active IP Right Cessation
- 1978-02-01 GB GB404378A patent/GB1565616A/en not_active Expired
- 1978-02-01 DE DE19782804293 patent/DE2804293A1/de active Granted
Also Published As
Publication number | Publication date |
---|---|
GB1565616A (en) | 1980-04-23 |
FR2378741B1 (en, 2012) | 1980-02-22 |
DE2804293C2 (en, 2012) | 1989-08-03 |
CA1097684A (fr) | 1981-03-17 |
FR2378741A1 (fr) | 1978-08-25 |
CH628014A5 (en) | 1982-02-15 |
NL7801057A (nl) | 1978-08-03 |
DE2804293A1 (de) | 1978-08-10 |
BE863196A (fr) | 1978-05-16 |
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