FR2378741A1 - Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques - Google Patents

Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques

Info

Publication number
FR2378741A1
FR2378741A1 FR7702959A FR7702959A FR2378741A1 FR 2378741 A1 FR2378741 A1 FR 2378741A1 FR 7702959 A FR7702959 A FR 7702959A FR 7702959 A FR7702959 A FR 7702959A FR 2378741 A1 FR2378741 A1 FR 2378741A1
Authority
FR
France
Prior art keywords
goxo
garyl
antiphlogistic
isovaleric acids
antalgic properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7702959A
Other languages
English (en)
French (fr)
Other versions
FR2378741B1 (en, 2012
Inventor
Henri Cousse
Gilbert Mousin
Jean-Pierre Rieu
Et Jean-Pierre Tarayre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Priority to FR7702959A priority Critical patent/FR2378741A1/fr
Priority to BE184536A priority patent/BE863196A/xx
Priority to NL7801057A priority patent/NL7801057A/xx
Priority to CA295,903A priority patent/CA1097684A/fr
Priority to ES466493A priority patent/ES466493A1/es
Priority to DE19782804293 priority patent/DE2804293A1/de
Priority to CH110878A priority patent/CH628014A5/fr
Priority to GB404378A priority patent/GB1565616A/en
Publication of FR2378741A1 publication Critical patent/FR2378741A1/fr
Application granted granted Critical
Publication of FR2378741B1 publication Critical patent/FR2378741B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7702959A 1977-02-01 1977-02-01 Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques Granted FR2378741A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR7702959A FR2378741A1 (fr) 1977-02-01 1977-02-01 Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques
BE184536A BE863196A (fr) 1977-02-01 1978-01-23 Acides alpha aryl alpha oxo isovaleriques doues de proprietes antiphologistiques et antalgistiques
CA295,903A CA1097684A (fr) 1977-02-01 1978-01-30 PROCEDE DE PREPARATION D'ACIDES.gamma.ARYL .gamma.OXO ISOVALERIQUES
NL7801057A NL7801057A (nl) 1977-02-01 1978-01-30 Gamma-aryl-gamma-oxo-isovaleriaanzuurderivaten en werkwijze ter bereiding van deze verbindingen.
ES466493A ES466493A1 (es) 1977-02-01 1978-01-31 Procedimiento de fabricacion de acidos a-aril-a -oxo-isovalericos.
DE19782804293 DE2804293A1 (de) 1977-02-01 1978-02-01 Alpha-aryl-gamma-oxo-isovaleriansaeure-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CH110878A CH628014A5 (en) 1977-02-01 1978-02-01 Gamma-aryl-gamma-oxoisovaleric acids having antiphlogistic and antalgic properties
GB404378A GB1565616A (en) 1977-02-01 1978-02-01 4-phenylbutyric acid dervatives process for their preparation and pharmaceutical compostions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7702959A FR2378741A1 (fr) 1977-02-01 1977-02-01 Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques

Publications (2)

Publication Number Publication Date
FR2378741A1 true FR2378741A1 (fr) 1978-08-25
FR2378741B1 FR2378741B1 (en, 2012) 1980-02-22

Family

ID=9186227

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7702959A Granted FR2378741A1 (fr) 1977-02-01 1977-02-01 Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques

Country Status (8)

Country Link
BE (1) BE863196A (en, 2012)
CA (1) CA1097684A (en, 2012)
CH (1) CH628014A5 (en, 2012)
DE (1) DE2804293A1 (en, 2012)
ES (1) ES466493A1 (en, 2012)
FR (1) FR2378741A1 (en, 2012)
GB (1) GB1565616A (en, 2012)
NL (1) NL7801057A (en, 2012)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS243570B1 (en) * 1984-08-31 1986-06-12 Miroslav Kuchar Omega-aryloxoalkane acids
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
AR002945A1 (es) * 1994-11-15 1998-05-27 Bayer Corp Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos
US5886022A (en) * 1995-06-05 1999-03-23 Bayer Corporation Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
GB9522615D0 (en) * 1995-11-03 1996-01-03 Pharmacia Spa 4-Phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
US5863915A (en) * 1996-05-15 1999-01-26 Bayer Corporation Substituted 4-arylbutyric acid derivatives as matrix metalloprotease
HRP970245B1 (en) 1996-05-15 2002-06-30 Bayer Ag Biaryl acetilenes as matrix metalloprotease inhibitors
TNSN97086A1 (fr) * 1996-05-15 2005-03-15 Bayer Corp La substitution des acides derivatives 4-albutyrique comme inhibiteurs de la matrice metalloprotease.

Also Published As

Publication number Publication date
GB1565616A (en) 1980-04-23
FR2378741B1 (en, 2012) 1980-02-22
DE2804293C2 (en, 2012) 1989-08-03
ES466493A1 (es) 1979-05-01
CA1097684A (fr) 1981-03-17
CH628014A5 (en) 1982-02-15
NL7801057A (nl) 1978-08-03
DE2804293A1 (de) 1978-08-10
BE863196A (fr) 1978-05-16

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