ES8503649A1 - Procedimiento para preparar esteres de acidos benzosulfonicos substituidos - Google Patents

Procedimiento para preparar esteres de acidos benzosulfonicos substituidos

Info

Publication number
ES8503649A1
ES8503649A1 ES533932A ES533932A ES8503649A1 ES 8503649 A1 ES8503649 A1 ES 8503649A1 ES 533932 A ES533932 A ES 533932A ES 533932 A ES533932 A ES 533932A ES 8503649 A1 ES8503649 A1 ES 8503649A1
Authority
ES
Spain
Prior art keywords
preparation
medicaments
acid esters
benzenesulfonic acid
substituted benzenesulfonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533932A
Other languages
English (en)
Other versions
ES533932A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES533932A0 publication Critical patent/ES533932A0/es
Publication of ES8503649A1 publication Critical patent/ES8503649A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/22—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/75—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/76—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/28—Y being a hetero atom, e.g. thiobiuret

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR ESTERES DE ACIDOS BENZOSULFONICOS SUSTITUIDOS.CONSISTE EN HACER REACCIONAR UN DERIVADO DE AMINO-UREA DE FORMULA (II) CON UN ISOTIOUREACARBOXILATO DE FORMULA (III), EN PRESENCIA DE UN DISOLVENTE COMO AGUA, ETANOL Y OTROS, EN PRESENCIA DE UN ACIDO INORGANICO COMO CLH, BRH Y OTROS O DE UN ACIDO ORGANICO COMO ACETICO, PROPIONICO Y OTROS Y A UNA TEMPERATURA ENTRE 0 Y 120JC, PARA OBTENER UN COMPUESTO DE FORMULA (I), SIENDO: R ALCOHILO DE CADENA RECTA O RAMIFICADA DE C 1 A 4; R, H, HALOGENO, CIANO, NITRO Y OTROS; R, H O -CO-R; R ALCOHILO O ALCOXIALCOHILO CON C 1 A 6 EN LA PARTE ALCOHILO EVENTUALMENTE SUSTITUIDO POR HALOGENO; Z FN-COOR; X -SO2-O O -0-SO2- Y N ES 1, 2 O 3.
ES533932A 1982-09-04 1984-07-02 Procedimiento para preparar esteres de acidos benzosulfonicos substituidos Expired ES8503649A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823232959 DE3232959A1 (de) 1982-09-04 1982-09-04 Substituierte benzolsulfonsaeureester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES533932A0 ES533932A0 (es) 1985-03-16
ES8503649A1 true ES8503649A1 (es) 1985-03-16

Family

ID=6172503

Family Applications (2)

Application Number Title Priority Date Filing Date
ES525335A Granted ES525335A0 (es) 1982-09-04 1983-09-02 Procedimiento para preparar esteres de acidos benzosulfonicos substituidos.
ES533932A Expired ES8503649A1 (es) 1982-09-04 1984-07-02 Procedimiento para preparar esteres de acidos benzosulfonicos substituidos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES525335A Granted ES525335A0 (es) 1982-09-04 1983-09-02 Procedimiento para preparar esteres de acidos benzosulfonicos substituidos.

Country Status (20)

Country Link
US (1) US4504490A (es)
EP (1) EP0105196B1 (es)
JP (1) JPS5976050A (es)
KR (1) KR840006335A (es)
AT (1) ATE28630T1 (es)
AU (1) AU1867983A (es)
CA (1) CA1214182A (es)
DE (2) DE3232959A1 (es)
DK (1) DK401683A (es)
ES (2) ES525335A0 (es)
FI (1) FI833119A (es)
GR (1) GR78941B (es)
HU (1) HU193531B (es)
IL (1) IL69640A0 (es)
MA (1) MA19892A1 (es)
NO (1) NO833158L (es)
NZ (1) NZ205468A (es)
PH (1) PH19980A (es)
PT (1) PT77285B (es)
ZA (1) ZA836515B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3713856A1 (de) * 1987-04-25 1988-11-17 Bayer Ag Sulfonsaeurearylesterhaltige aromatische diamine, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der herstellung von polyurethankunststoffen
SE9103745D0 (sv) * 1991-12-18 1991-12-18 Wikstroem Haakan Aryl-triflates and related compounds
EP0742208A1 (en) * 1995-05-05 1996-11-13 Grelan Pharmaceutical Co., Ltd. 2-Ureido-benzamide derivatives
NZ523086A (en) 2000-06-20 2007-07-27 Novartis Ag Method of administering bisphosphonates
WO2012142698A1 (en) * 2011-04-20 2012-10-26 Universite Laval Alkylurea derivatives active against cancer cells
DE102020112411B3 (de) * 2020-05-07 2021-05-27 Papierfabrik August Koehler Se Wärmeempfindliches Aufzeichnungsmaterial

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2441201C2 (de) * 1974-08-28 1986-08-07 Hoechst Ag, 6230 Frankfurt Anthelminthisch wirksame 2-Carbalkoxyamino-5(6)-phenyl-sulfonyloxy-benzimidazole und Verfahren zu ihrer Herstellung
DE2441202C2 (de) * 1974-08-28 1986-05-28 Hoechst Ag, 6230 Frankfurt 2-Carbalkoxyamino-benzimidazolyl-5(6)-sulfonsäure-phenylester, Verfahren zu ihrer Herstellung und diese enthaltende anthelmintische Mittel
DE2608238A1 (de) * 1976-02-28 1977-09-08 Hoechst Ag Substituierte phenylguanidine und verfahren zu ihrer herstellung
DE2653766A1 (de) * 1976-11-26 1978-06-01 Bayer Ag Substituierte benzolsulfonsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2836385A1 (de) * 1978-08-19 1980-03-06 Hoechst Ag Monocarboxylate von phenylguanidinsulfonsaeureestern, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
ES8500898A1 (es) 1984-11-01
IL69640A0 (en) 1983-12-30
KR840006335A (ko) 1984-11-29
ATE28630T1 (de) 1987-08-15
FI833119A0 (fi) 1983-09-01
FI833119A (fi) 1984-03-05
EP0105196A2 (de) 1984-04-11
ES525335A0 (es) 1984-11-01
DK401683D0 (da) 1983-09-02
ZA836515B (en) 1984-04-25
MA19892A1 (fr) 1984-04-01
EP0105196A3 (en) 1985-04-03
CA1214182A (en) 1986-11-18
PT77285A (en) 1983-10-01
DE3372756D1 (en) 1987-09-03
ES533932A0 (es) 1985-03-16
GR78941B (es) 1984-10-02
JPS5976050A (ja) 1984-04-28
PH19980A (en) 1986-08-26
PT77285B (en) 1986-04-09
EP0105196B1 (de) 1987-07-29
NO833158L (no) 1984-03-05
HU193531B (en) 1987-10-28
US4504490A (en) 1985-03-12
DK401683A (da) 1984-03-05
DE3232959A1 (de) 1984-03-08
NZ205468A (en) 1985-07-31
AU1867983A (en) 1984-03-08

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