ES457988A1 - Un procedimiento de preparacion de un derivado de fenilpipe-razina. - Google Patents

Un procedimiento de preparacion de un derivado de fenilpipe-razina.

Info

Publication number
ES457988A1
ES457988A1 ES457988A ES457988A ES457988A1 ES 457988 A1 ES457988 A1 ES 457988A1 ES 457988 A ES457988 A ES 457988A ES 457988 A ES457988 A ES 457988A ES 457988 A1 ES457988 A1 ES 457988A1
Authority
ES
Spain
Prior art keywords
formula
group
vii
alkyl
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES457988A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of ES457988A1 publication Critical patent/ES457988A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES457988A 1976-04-23 1977-04-20 Un procedimiento de preparacion de un derivado de fenilpipe-razina. Expired ES457988A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16526/76A GB1575904A (en) 1976-04-23 1976-04-23 Phenyl piperazines

Publications (1)

Publication Number Publication Date
ES457988A1 true ES457988A1 (es) 1978-07-16

Family

ID=10078930

Family Applications (2)

Application Number Title Priority Date Filing Date
ES457988A Expired ES457988A1 (es) 1976-04-23 1977-04-20 Un procedimiento de preparacion de un derivado de fenilpipe-razina.
ES467948A Expired ES467948A1 (es) 1976-04-23 1978-03-16 Un procedimiento para la preparacion de un derivado de fe- nilpiperazina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES467948A Expired ES467948A1 (es) 1976-04-23 1978-03-16 Un procedimiento para la preparacion de un derivado de fe- nilpiperazina.

Country Status (34)

Country Link
JP (1) JPS52151183A (fr)
AR (2) AR222003A1 (fr)
AT (1) AT355579B (fr)
AU (1) AU514822B2 (fr)
BE (1) BE853899A (fr)
BG (2) BG27746A3 (fr)
CA (1) CA1087617A (fr)
CH (2) CH633009A5 (fr)
CS (1) CS196360B2 (fr)
DD (1) DD129790A5 (fr)
DE (1) DE2717415A1 (fr)
DK (1) DK176177A (fr)
ES (2) ES457988A1 (fr)
FI (1) FI63937C (fr)
FR (1) FR2348925A1 (fr)
GB (1) GB1575904A (fr)
GR (1) GR64084B (fr)
HU (1) HU176820B (fr)
IE (1) IE44730B1 (fr)
IL (1) IL51787A (fr)
LU (1) LU77170A1 (fr)
MX (1) MX4596E (fr)
NL (1) NL7704456A (fr)
NO (1) NO146710C (fr)
NZ (1) NZ183715A (fr)
OA (1) OA05643A (fr)
PH (1) PH14124A (fr)
PL (1) PL117466B1 (fr)
PT (1) PT66452B (fr)
RO (1) RO72831A (fr)
SE (1) SE7704536L (fr)
SU (2) SU664564A3 (fr)
YU (1) YU104477A (fr)
ZA (1) ZA771849B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1601310A (en) * 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
DE3142608A1 (de) * 1981-10-28 1983-05-05 Basf Ag, 6700 Ludwigshafen Polyazofarbstoffe
JPH07157477A (ja) * 1993-12-02 1995-06-20 Asahi Kagaku Kogyo Kk チアゾール誘導体の製造方法
NZ281718A (en) * 1994-03-11 1997-08-22 Yamanouchi Pharma Co Ltd Heterocyclically-substituted (condensed) thiazoles
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
TW200804309A (en) 2006-02-28 2008-01-16 Helicon Therapeutics Inc Therapeutic piperazines
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines

Also Published As

Publication number Publication date
SE7704536L (sv) 1977-10-24
LU77170A1 (fr) 1979-01-18
ZA771849B (en) 1978-11-29
SU664564A3 (ru) 1979-05-25
GB1575904A (en) 1980-10-01
IE44730L (en) 1977-10-23
PH14124A (en) 1981-02-26
ES467948A1 (es) 1978-11-01
PT66452A (en) 1977-05-01
CS196360B2 (en) 1980-03-31
HU176820B (en) 1981-05-28
GR64084B (en) 1980-01-21
FI771287A (fr) 1977-10-24
DK176177A (da) 1977-10-24
NO771398L (no) 1977-10-25
AU514822B2 (en) 1981-02-26
AR222635A1 (es) 1981-06-15
BG28055A3 (en) 1980-02-25
FI63937C (fi) 1983-09-12
SU727146A3 (ru) 1980-04-05
NO146710C (no) 1982-11-24
FR2348925B1 (fr) 1980-04-11
IL51787A (en) 1980-02-29
RO72831A (fr) 1983-08-03
NZ183715A (en) 1980-04-28
BG27746A3 (en) 1979-12-12
AU2438677A (en) 1978-10-26
FI63937B (fi) 1983-05-31
YU104477A (en) 1983-01-21
CH633009A5 (en) 1982-11-15
PL117466B1 (en) 1981-08-31
DD129790A5 (de) 1978-02-08
OA05643A (fr) 1981-04-30
ATA285177A (de) 1979-08-15
IE44730B1 (en) 1982-03-10
NL7704456A (nl) 1977-10-25
AR222003A1 (es) 1981-04-15
AT355579B (de) 1980-03-10
JPS52151183A (en) 1977-12-15
RO72831B (ro) 1983-07-30
BE853899A (fr) 1977-10-24
DE2717415A1 (de) 1977-11-10
MX4596E (es) 1982-06-25
CH625802A5 (en) 1981-10-15
CA1087617A (fr) 1980-10-14
NO146710B (no) 1982-08-16
PT66452B (en) 1979-03-09
IL51787A0 (en) 1977-05-31
FR2348925A1 (fr) 1977-11-18
PL197550A1 (pl) 1979-05-21

Similar Documents

Publication Publication Date Title
DE3271269D1 (en) Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same
NO792119L (no) Analogifremgangsmaate for fremstilling av 2-(2-alkoksyetyl)-2`hydroksyl-6,7-benzomorfaner og syreaddisjonssalter derav
HU904785D0 (en) Process for the production of medicaments
AU6747687A (en) New derivatives of decahydroquinoline,their preparation process, the preparation intermediates, their use as medicaments and the compositions containing them
SE7906472L (sv) Nya 3-(aminoetyl)-fenol-derivat och salter derav, sett for framstellning och anvendning derav sasom lekemedel samt farmaceutiska kompositioner innehallande dessa foreningar
DE69311118D1 (de) Phosphono-arylethanolamin-verbindungen mit antihyperglykämischer und/oder antiobeser wirkung
ES457988A1 (es) Un procedimiento de preparacion de un derivado de fenilpipe-razina.
NO164351C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
NO160445C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser.
DK37580A (da) 4,5-dihydro-4-oxofuran-2-carboxylsyrederivater samt deres fremstilling og anvendelse
JPS5283396A (en) Novel compound physiologically acceptable salts thereof process for preparing same and medical composition containing same
ES8202818A1 (es) Un procedimiento para preparar derivados de tetrazolilcuma- rina
ES8601982A1 (es) Procedimiento para la preparacion de derivados diaminicos
SE8903312L (sv) New 2-carbonyl substituted n,n'-di-(trimethoxybenzol)piperazines, process for preparing the same and therapeutical compounds containing them
ATE29496T1 (de) Tetrahydro-beta-carbolin-derivate und verfahren fuer ihre herstellung.
ES8201528A1 (es) Un procedimiento para la preparacion de nuevos derivados de 1,1'-bifenil-2-il-alquilamina
SE8301785L (sv) Sett att framstella 2-tiofen-ettiksyraderivat och mellanprodukter erforderliga for deras framstellning
IE810080L (en) Triazolobenzopyrans
ES2024332A6 (es) Procedimiento para la obtencion de nuevas sulfonamidas.
US4027030A (en) Certain thiazole-carboxamides and their pharmaceutical utility
GB1469410A (en) Benzodioxole derivatives
SE7901034L (sv) Nya anilider med antitussiv verkan och forfarande for framstellning derav
ES488388A1 (es) Procedimiento de preparacion de derivados hidroxilados del tiazol
SE8903313L (sv) Nya 2-metoxikarbonyl-substituerade n,n'-di-(trimetoxibensoyl)-piperaziner, foerfarande foer framstaellning daerav och terapeutiska foereningar innehaallande dem
IE40836B1 (en) Benzoxazoline derivatives,their preparation and use as plant growth regulants