ES457385A1 - Procedimiento para preparar derivados de prostaglandinas. - Google Patents

Procedimiento para preparar derivados de prostaglandinas.

Info

Publication number
ES457385A1
ES457385A1 ES457385A ES457385A ES457385A1 ES 457385 A1 ES457385 A1 ES 457385A1 ES 457385 A ES457385 A ES 457385A ES 457385 A ES457385 A ES 457385A ES 457385 A1 ES457385 A1 ES 457385A1
Authority
ES
Spain
Prior art keywords
methyl
same
ethyl
preparing
prostaglandin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES457385A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of ES457385A1 publication Critical patent/ES457385A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126Acids containing more than four carbon atoms
    • C07C53/128Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
ES457385A 1976-03-31 1977-03-31 Procedimiento para preparar derivados de prostaglandinas. Expired ES457385A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49325A IL49325A (en) 1976-03-31 1976-03-31 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ES457385A1 true ES457385A1 (es) 1978-02-01

Family

ID=11048789

Family Applications (1)

Application Number Title Priority Date Filing Date
ES457385A Expired ES457385A1 (es) 1976-03-31 1977-03-31 Procedimiento para preparar derivados de prostaglandinas.

Country Status (18)

Country Link
US (1) US4115401A (enEXAMPLES)
JP (1) JPS52142060A (enEXAMPLES)
BE (1) BE852941A (enEXAMPLES)
CA (1) CA1074804A (enEXAMPLES)
CH (2) CH624101A5 (enEXAMPLES)
DD (1) DD130352A5 (enEXAMPLES)
DE (1) DE2714129A1 (enEXAMPLES)
ES (1) ES457385A1 (enEXAMPLES)
FR (1) FR2346332A1 (enEXAMPLES)
GB (1) GB1574246A (enEXAMPLES)
HU (1) HU178040B (enEXAMPLES)
IL (1) IL49325A (enEXAMPLES)
IT (1) IT1075373B (enEXAMPLES)
NL (1) NL7703503A (enEXAMPLES)
NO (1) NO149428C (enEXAMPLES)
PL (3) PL107643B1 (enEXAMPLES)
SE (1) SE417603B (enEXAMPLES)
SU (3) SU676162A3 (enEXAMPLES)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7905375A (nl) * 1978-07-11 1980-01-15 Glaxo Group Ltd Prostanoiden, werkwijze voor het bereiden daarvan, en daarop gebaseerde farmaceutische preparaten.
US4320136A (en) * 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4530933A (en) * 1982-12-27 1985-07-23 E. I. Du Pont De Nemours And Company 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents
US4456613A (en) * 1982-12-27 1984-06-26 E. I. Du Pont De Nemours And Company 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof
OA12117A (en) 1999-12-22 2006-05-04 Pfizer Prod Inc EP4 receptor selective agonists in the treatment of osteoporosis.
EA200300379A1 (ru) * 2000-11-27 2003-08-28 Пфайзер Продактс Инк. Селективные агонисты рецептора ep4 в лечении остеопороза
JP2004521954A (ja) 2001-07-16 2004-07-22 エフ.ホフマン−ラ ロシュ アーゲー Ep4受容体作用薬としてのプロスタグランジン類似体
CN100371322C (zh) * 2001-07-16 2008-02-27 霍夫曼-拉罗奇有限公司 作为前列腺素类化合物激动剂的2-吡咯烷酮衍生物
US7608637B2 (en) * 2001-07-23 2009-10-27 Ono Pharmaceutical Co., Ltd. Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as the active ingredient
EP1481976B1 (en) 2002-03-05 2012-11-07 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
AU2003209571A1 (en) * 2002-03-18 2003-09-29 Pfizer Products Inc. Use of selective ep4 receptor agonists for the treatment of liver failure, loss of patency of the ductus arteriosus, glaucoma or ocular hypertension
AU2004203905A1 (en) * 2003-01-10 2004-07-29 F. Hoffmann-La Roche Ag 2-piperidone derivatives as prostaglandin agonists
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US20080058375A1 (en) * 2004-01-08 2008-03-06 Elworthy Todd R 2-Piperidone derivatives as prostaglandin antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones

Also Published As

Publication number Publication date
NL7703503A (nl) 1977-10-04
SE7703698L (sv) 1977-10-01
SE417603B (sv) 1981-03-30
CH624101A5 (enEXAMPLES) 1981-07-15
NO149428B (no) 1984-01-09
PL197005A1 (pl) 1978-10-09
PL107544B1 (pl) 1980-02-29
SU676162A3 (ru) 1979-07-25
IT1075373B (it) 1985-04-22
CA1074804A (en) 1980-04-01
GB1574246A (en) 1980-09-03
FR2346332A1 (fr) 1977-10-28
BE852941A (fr) 1977-09-28
DE2714129A1 (de) 1977-10-13
PL107643B1 (pl) 1980-02-29
NO149428C (no) 1984-04-18
US4115401A (en) 1978-09-19
HU178040B (en) 1982-02-28
IL49325A0 (en) 1976-05-31
SU715019A3 (ru) 1980-02-05
JPS52142060A (en) 1977-11-26
NO771134L (no) 1977-10-03
CH628032A5 (fr) 1982-02-15
IL49325A (en) 1979-11-30
SU837321A3 (ru) 1981-06-07
PL108289B1 (pl) 1980-03-31
FR2346332B1 (enEXAMPLES) 1980-05-09
DD130352A5 (de) 1978-03-22

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