ES453963A2 - Procedimiento para la preparacion de anilidas de acido 2-hi-droxietilidencianoacetico. - Google Patents
Procedimiento para la preparacion de anilidas de acido 2-hi-droxietilidencianoacetico.Info
- Publication number
- ES453963A2 ES453963A2 ES453963A ES453963A ES453963A2 ES 453963 A2 ES453963 A2 ES 453963A2 ES 453963 A ES453963 A ES 453963A ES 453963 A ES453963 A ES 453963A ES 453963 A2 ES453963 A2 ES 453963A2
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- cyanoacetic acid
- acid anilide
- anilide derivatives
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XCTQPMCULSZKLT-UHFFFAOYSA-N 2-cyano-n-phenylacetamide Chemical class N#CCC(=O)NC1=CC=CC=C1 XCTQPMCULSZKLT-UHFFFAOYSA-N 0.000 title 1
- GLPCMJHDPXSCPC-UHFFFAOYSA-N 2-cyano-4-hydroxy-n-phenylbut-2-enamide Chemical class OCC=C(C#N)C(=O)NC1=CC=CC=C1 GLPCMJHDPXSCPC-UHFFFAOYSA-N 0.000 abstract 1
- OPXYNEYEDHAXOM-UHFFFAOYSA-N 3-oxobutanenitrile Chemical compound CC(=O)CC#N OPXYNEYEDHAXOM-UHFFFAOYSA-N 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 239000002543 antimycotic Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000855 fungicidal effect Effects 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752555685 DE2555685A1 (de) | 1975-12-11 | 1975-12-11 | Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
| DE19752557003 DE2557003A1 (de) | 1975-12-18 | 1975-12-18 | Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES453963A2 true ES453963A2 (es) | 1978-05-01 |
Family
ID=25769723
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES453963A Expired ES453963A2 (es) | 1975-12-11 | 1976-12-04 | Procedimiento para la preparacion de anilidas de acido 2-hi-droxietilidencianoacetico. |
| ES466542A Expired ES466542A2 (es) | 1975-12-11 | 1978-02-01 | Mejoras introducidas en el objeto de la patente principal num. 448.385 presentada el 31-5-76, por:procedimiento para la preparacion de anilidas de acido 2-hidroxietilidenciano- acetico |
| ES475109A Expired ES475109A1 (es) | 1975-12-11 | 1978-11-15 | Procedimiento para la preparacion de aniladas de acido hi- droxietilidencianoacetico. |
| ES475111A Expired ES475111A1 (es) | 1975-12-11 | 1978-11-15 | Procedimiento para la preparacion de anilidas de acido hi- droxietilidencianoacetico. |
| ES475110A Expired ES475110A1 (es) | 1975-12-11 | 1978-11-15 | Procedimiento para la preparacion de anilinas de acido hi- droxietilidencianoacrtico. |
| ES475108A Expired ES475108A2 (es) | 1975-12-11 | 1978-11-15 | Mejoras introducidas en el objeto de la patente principal por procedimiento para la preparacion de anilidas de acido 2-hidroxietilidencianoacetico. |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466542A Expired ES466542A2 (es) | 1975-12-11 | 1978-02-01 | Mejoras introducidas en el objeto de la patente principal num. 448.385 presentada el 31-5-76, por:procedimiento para la preparacion de anilidas de acido 2-hidroxietilidenciano- acetico |
| ES475109A Expired ES475109A1 (es) | 1975-12-11 | 1978-11-15 | Procedimiento para la preparacion de aniladas de acido hi- droxietilidencianoacetico. |
| ES475111A Expired ES475111A1 (es) | 1975-12-11 | 1978-11-15 | Procedimiento para la preparacion de anilidas de acido hi- droxietilidencianoacetico. |
| ES475110A Expired ES475110A1 (es) | 1975-12-11 | 1978-11-15 | Procedimiento para la preparacion de anilinas de acido hi- droxietilidencianoacrtico. |
| ES475108A Expired ES475108A2 (es) | 1975-12-11 | 1978-11-15 | Mejoras introducidas en el objeto de la patente principal por procedimiento para la preparacion de anilidas de acido 2-hidroxietilidencianoacetico. |
Country Status (12)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0088545B1 (en) * | 1982-03-05 | 1985-12-11 | Fbc Limited | Fungicidal cyanopropenoates and compositions containing them |
| DE3534440A1 (de) * | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
| GB8619432D0 (en) * | 1986-08-08 | 1986-09-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| GB8619433D0 (en) * | 1986-08-08 | 1986-09-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| US6355678B1 (en) * | 1998-06-29 | 2002-03-12 | Parker Hughes Institute | Inhibitors of the EGF-receptor tyrosine kinase and methods for their use |
| WO2010013159A1 (en) * | 2008-07-29 | 2010-02-04 | Alembic Limited | A process for the preparation of teriflunomide |
-
1976
- 1976-12-03 DK DK545976A patent/DK545976A/da not_active Application Discontinuation
- 1976-12-04 ES ES453963A patent/ES453963A2/es not_active Expired
- 1976-12-06 NL NL7613547A patent/NL7613547A/xx not_active Application Discontinuation
- 1976-12-09 LU LU76354A patent/LU76354A1/xx unknown
- 1976-12-09 IT IT30233/76A patent/IT1124789B/it active
- 1976-12-10 CH CH1560476A patent/CH632487A5/de not_active IP Right Cessation
- 1976-12-10 CA CA267,670A patent/CA1092133A/en not_active Expired
- 1976-12-10 IE IE2706/76A patent/IE44047B1/en unknown
- 1976-12-10 MX MX765215U patent/MX4758E/es unknown
- 1976-12-11 JP JP51148336A patent/JPS5273830A/ja active Pending
- 1976-12-13 GB GB51910/76A patent/GB1571990A/en not_active Expired
- 1976-12-13 FR FR7637514A patent/FR2334350A2/fr active Granted
-
1978
- 1978-02-01 ES ES466542A patent/ES466542A2/es not_active Expired
- 1978-11-15 ES ES475109A patent/ES475109A1/es not_active Expired
- 1978-11-15 ES ES475111A patent/ES475111A1/es not_active Expired
- 1978-11-15 ES ES475110A patent/ES475110A1/es not_active Expired
- 1978-11-15 ES ES475108A patent/ES475108A2/es not_active Expired
-
1981
- 1981-04-14 CH CH250681A patent/CH630342A5/de not_active IP Right Cessation
- 1981-04-14 CH CH250881A patent/CH629757A5/de not_active IP Right Cessation
- 1981-04-14 CH CH250481A patent/CH630341A5/de not_active IP Right Cessation
- 1981-04-14 CH CH250781A patent/CH629756A5/de not_active IP Right Cessation
- 1981-04-14 CH CH250581A patent/CH629755A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK545976A (da) | 1977-06-12 |
| MX4758E (es) | 1982-09-03 |
| ES475108A2 (es) | 1979-08-01 |
| CH629756A5 (en) | 1982-05-14 |
| CA1092133A (en) | 1980-12-23 |
| GB1571990A (en) | 1980-07-23 |
| CH629755A5 (en) | 1982-05-14 |
| IE44047L (en) | 1977-06-11 |
| ES475110A1 (es) | 1979-05-01 |
| NL7613547A (nl) | 1977-06-14 |
| FR2334350B2 (enrdf_load_stackoverflow) | 1980-03-07 |
| CH630342A5 (en) | 1982-06-15 |
| JPS5273830A (en) | 1977-06-21 |
| CH632487A5 (en) | 1982-10-15 |
| ES466542A2 (es) | 1979-01-16 |
| CH629757A5 (en) | 1982-05-14 |
| CH630341A5 (en) | 1982-06-15 |
| LU76354A1 (enrdf_load_stackoverflow) | 1977-06-24 |
| ES475109A1 (es) | 1979-04-16 |
| ES475111A1 (es) | 1979-05-01 |
| IE44047B1 (en) | 1981-07-29 |
| FR2334350A2 (fr) | 1977-07-08 |
| IT1124789B (it) | 1986-05-14 |
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