ES326315A1 - Procedure for the preparation of new substitute methanobenzazcines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new substitute methanobenzazcines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES326315A1
ES326315A1 ES0326315A ES326315A ES326315A1 ES 326315 A1 ES326315 A1 ES 326315A1 ES 0326315 A ES0326315 A ES 0326315A ES 326315 A ES326315 A ES 326315A ES 326315 A1 ES326315 A1 ES 326315A1
Authority
ES
Spain
Prior art keywords
radical
compound
formula
group
alkanoyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0326315A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES326315A1 publication Critical patent/ES326315A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Connections Arranged To Contact A Plurality Of Conductors (AREA)
  • Clamps And Clips (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Abstract

Process for the preparation of new substituted metanobezazocins, of the general formula I ** (See formula) ** in which R1 means hydrogen, halogen, the trifluoromethyl group or the hydroxyl group, R 2 means hydrogen, the hydroxy group or a lower alkoxy or lower alkanoyloxy radical, and Y means nitrogen or an alkyl, alkenyl or lower alkynyl radical, the alkyl or alkenyl radical may be substituted by a halogen atom, a hydroxylic group or a phenyl, nitrophenyl or aminophenyl radical, or else it means a cycloalkylmethyl radical, and its acid addition salts, characterized by treating a compound of the general formula II ** (See formula) ** in which Y, R1 and R2 have the meaning already stated, with a reducing agent suitable for the reduction of a carbonyl group to a methylene group and, if desired, a compound of the formula I in which R2 means a lower alkoxy radical or alkanoyloxy, by cleavage with ether or by hydrolysis, in a compound also encompassed by formula I, in which R2 signifies the hydroxyl group; and, if desired, converting such a compound, by treatment with an alkylating or alkanoylating agent corresponding to the meaning of R2, into a compound of the formula I in which R2 signifies a lower alkoxy or alkanoyloxy radical; and, if desired, to transform a compound thus obtained into an acid addition salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES0326315A 1965-05-05 1966-05-04 Procedure for the preparation of new substitute methanobenzazcines. (Machine-translation by Google Translate, not legally binding) Expired ES326315A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45347265A 1965-05-05 1965-05-05

Publications (1)

Publication Number Publication Date
ES326315A1 true ES326315A1 (en) 1967-07-01

Family

ID=23800715

Family Applications (3)

Application Number Title Priority Date Filing Date
ES0326314A Expired ES326314A1 (en) 1965-05-05 1966-05-04 Procedure for the synthesis of new substitute methanobenzazokins. (Machine-translation by Google Translate, not legally binding)
ES0326316A Expired ES326316A1 (en) 1965-05-05 1966-05-04 Procedure for the synthesis of new metanobenzazocines. (Machine-translation by Google Translate, not legally binding)
ES0326315A Expired ES326315A1 (en) 1965-05-05 1966-05-04 Procedure for the preparation of new substitute methanobenzazcines. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES0326314A Expired ES326314A1 (en) 1965-05-05 1966-05-04 Procedure for the synthesis of new substitute methanobenzazokins. (Machine-translation by Google Translate, not legally binding)
ES0326316A Expired ES326316A1 (en) 1965-05-05 1966-05-04 Procedure for the synthesis of new metanobenzazocines. (Machine-translation by Google Translate, not legally binding)

Country Status (12)

Country Link
AT (2) AT260266B (en)
BE (2) BE680526A (en)
BR (2) BR6679232D0 (en)
CH (2) CH469712A (en)
DE (2) DE1695073A1 (en)
DK (2) DK124200B (en)
ES (3) ES326314A1 (en)
GB (2) GB1152984A (en)
IL (2) IL25700A (en)
NL (2) NL6606057A (en)
NO (2) NO123721B (en)
SE (2) SE341188B (en)

Also Published As

Publication number Publication date
BE680525A (en) 1966-11-04
SE341188B (en) 1971-12-20
NO123387B (en) 1971-11-08
CH469712A (en) 1969-03-15
DK125092B (en) 1972-12-27
AT260265B (en) 1968-02-26
CH470395A (en) 1969-03-31
NL6606057A (en) 1966-11-07
GB1152984A (en) 1969-05-21
IL25700A (en) 1971-02-25
NL6606056A (en) 1966-11-07
IL25699A (en) 1971-05-26
DK124200B (en) 1972-09-25
ES326316A1 (en) 1967-03-01
SE341189B (en) 1971-12-20
BR6679232D0 (en) 1973-10-23
NO123721B (en) 1972-01-03
GB1154570A (en) 1969-06-11
BR6679231D0 (en) 1973-09-18
BE680526A (en) 1966-11-04
DE1695072A1 (en) 1970-12-10
ES326314A1 (en) 1967-03-01
DE1695073A1 (en) 1970-12-10
AT260266B (en) 1968-02-26

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