ES421182A1 - Propanolamine derivatives - Google Patents

Propanolamine derivatives

Info

Publication number
ES421182A1
ES421182A1 ES421182A ES421182A ES421182A1 ES 421182 A1 ES421182 A1 ES 421182A1 ES 421182 A ES421182 A ES 421182A ES 421182 A ES421182 A ES 421182A ES 421182 A1 ES421182 A1 ES 421182A1
Authority
ES
Spain
Prior art keywords
group
nhr2
halogen atom
general formula
hydroxy group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES421182A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Original Assignee
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp filed Critical Pfizer Corp
Publication of ES421182A1 publication Critical patent/ES421182A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for preparing 1-phenoxy-3-phenoxyethylamino-2-propanoles, of general formula: **(See formula)** where R represents a hydrogen atom or a protecting group for a hydroxy group; R1 represents a halogen atom or a lower alkyl, alkenyl, alkoxy or alkenoxy group; and R2 represents a hydrogen atom or a benzyl group; characterized in that it comprises reacting a compound of the general formula: **(See formula)** with a compound of general formula: **(See formula)** where R and R1 are defined as above; one of the radicals Z1 and Z3 is a group -NHR2 where R2 is defined as above; in the event that Z1 is a -NHR2 group, then R2 is a hydroxy group and Z3 is a halogen atom or other suitable "leaving" group; in the event that Z3 is a -NHR2 group, then Z1 is a halogen atom or other suitable leaving group and Z2 is a hydroxy group, or Z1 and Z2 together represent an epoxy group and R is a protecting group for a hydroxy group . (Machine-translation by Google Translate, not legally binding)
ES421182A 1972-12-05 1973-12-05 Propanolamine derivatives Expired ES421182A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5604672A GB1398738A (en) 1972-12-05 1972-12-05 Propanolamine derivatives

Publications (1)

Publication Number Publication Date
ES421182A1 true ES421182A1 (en) 1976-04-16

Family

ID=10475588

Family Applications (1)

Application Number Title Priority Date Filing Date
ES421182A Expired ES421182A1 (en) 1972-12-05 1973-12-05 Propanolamine derivatives

Country Status (13)

Country Link
JP (1) JPS49100046A (en)
AU (1) AU473444B2 (en)
BE (1) BE808094A (en)
CA (1) CA1020946A (en)
CH (1) CH591424A5 (en)
DE (1) DE2357849A1 (en)
ES (1) ES421182A1 (en)
FR (1) FR2208668B1 (en)
GB (1) GB1398738A (en)
IE (1) IE38872B1 (en)
IL (1) IL43726A (en)
LU (1) LU68914A1 (en)
NL (1) NL7316652A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165384A (en) * 1974-11-01 1979-08-21 Aktiebolaget Hassle Amide substituted phenoxy propanol amines
FI791727A (en) * 1978-06-05 1979-12-06 Ciba Geigy Ag FOER REFRIGERATION FOR AMMOAL ALCOHOL
DD150456A5 (en) * 1979-03-01 1981-09-02 Ciba Geigy Ag PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-AMINO-1,2-PROPANDIOL
JPS5726653A (en) * 1980-05-09 1982-02-12 Ciba Geigy Ag Substituted phenyl ether
GR74992B (en) * 1980-08-13 1984-07-12 Ciba Geigy Ag
US5254595A (en) * 1988-12-23 1993-10-19 Elf Sanofi Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE368197B (en) * 1968-11-18 1974-06-24 Pfizer
DE2023829C3 (en) * 1970-05-15 1979-06-21 Pfizer Corp., Colon (Panama) Nuclear-substituted 3-phenoxy-lphenoxyalkyl-aminopropane-2-oIe, process for their production and pharmaceuticals

Also Published As

Publication number Publication date
IL43726A (en) 1977-07-31
BE808094A (en) 1974-05-30
AU6298973A (en) 1975-05-29
FR2208668A1 (en) 1974-06-28
FR2208668B1 (en) 1977-01-28
CH591424A5 (en) 1977-09-15
NL7316652A (en) 1974-06-07
DE2357849A1 (en) 1974-06-06
LU68914A1 (en) 1975-08-20
IE38872L (en) 1974-06-05
AU473444B2 (en) 1976-06-24
IL43726A0 (en) 1974-03-14
GB1398738A (en) 1975-06-25
IE38872B1 (en) 1978-06-21
JPS49100046A (en) 1974-09-20
CA1020946A (en) 1977-11-15

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