ES305738A1 - Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES305738A1
ES305738A1 ES0305738A ES305738A ES305738A1 ES 305738 A1 ES305738 A1 ES 305738A1 ES 0305738 A ES0305738 A ES 0305738A ES 305738 A ES305738 A ES 305738A ES 305738 A1 ES305738 A1 ES 305738A1
Authority
ES
Spain
Prior art keywords
phenyl
radical
translation
preparation
means hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0305738A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES305738A1 publication Critical patent/ES305738A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Process for the preparation of new substituted 5-phenyl-6,7-benzomorpans, of the general formula I ** (See formula) ** in which R1 means hydrogen, halogen or the hydroxyl group, R2 means hydrogen, the hydroxyl group, an alkoxy or lower alkanoyloxy radical, Y means hydrogen, an alkyl, alkenyl or lower alkinyl radical, wherein the alkyl or alkenyl radical can be substituted by a halogen atom, a hydroxyl group, a cycloalkylmethyl radical, phenyl, nitrophenyl or aminophenyl, and X means hydrogen or a lower alkyl radical, and its acid addition salts, characterized in that a compound of the general formula II, ** (See formula) ** it is cyclized by treatment with a Lewis acid and the obtained compound of the general formula I, if desired, is transformed with an inorganic or organic acid into a salt. (Machine-translation by Google Translate, not legally binding)
ES0305738A 1963-11-07 1964-11-06 Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) Expired ES305738A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32206363A 1963-11-07 1963-11-07

Publications (1)

Publication Number Publication Date
ES305738A1 true ES305738A1 (en) 1965-05-01

Family

ID=23253254

Family Applications (3)

Application Number Title Priority Date Filing Date
ES0305740A Expired ES305740A1 (en) 1963-11-07 1964-11-06 Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding)
ES0305738A Expired ES305738A1 (en) 1963-11-07 1964-11-06 Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding)
ES0305739A Expired ES305739A1 (en) 1963-11-07 1964-11-06 Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES0305740A Expired ES305740A1 (en) 1963-11-07 1964-11-06 Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES0305739A Expired ES305739A1 (en) 1963-11-07 1964-11-06 Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding)

Country Status (3)

Country Link
AT (5) AT251201B (en)
ES (3) ES305740A1 (en)
FR (2) FR4040M (en)

Also Published As

Publication number Publication date
AT255033B (en) 1967-06-26
AT257055B (en) 1967-09-25
ES305740A1 (en) 1965-04-16
AT251201B (en) 1966-12-27
AT254399B (en) 1967-05-26
FR4024M (en) 1966-03-21
FR4040M (en) 1966-03-28
ES305739A1 (en) 1965-04-16
AT254398B (en) 1967-05-26

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