ES305739A1 - Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES305739A1 ES305739A1 ES0305739A ES305739A ES305739A1 ES 305739 A1 ES305739 A1 ES 305739A1 ES 0305739 A ES0305739 A ES 0305739A ES 305739 A ES305739 A ES 305739A ES 305739 A1 ES305739 A1 ES 305739A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- radical
- general formula
- phenyl
- hydroxyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heat Sensitive Colour Forming Recording (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Catalysts (AREA)
Abstract
Process for the preparation of new substituted 5-phenyl-6,7-benzomorpans, of the general formula I ** (See formula) ** in which R1 means hydrogen, halogen or the hydroxyl group, r2 means hydrogen, the hydroxyl group, an alkoxy or lower alkanoyloxy radical, Y means an alkyl, alkenyl or lower alkynyl radical, wherein the alkyl or alkenyl radical may be substituted by a halogen atom, a hydroxyl group, a cycloalkylmethyl, phenyl, nitrophenyl or aminophenyl radical, as well as X means hydrogen or a lower alkyl radical, and its acid addition salts, characterized in that a compound of the general formula II, ** (See formula) ** in which X, R1 and R2 have the significance indicated above, it is reacted in the presence of an acid-binding agent, with a compound of the general formula III, Y - Hal (III) in which And it has the significance indicated above and Hal means a halogen atom, * whereby a compound of the general formula I is originated, and if desired a compound of the general formula I, in which R 2 signifies an alkoxy or lower alkanoyloxy radical, is transformed by cleavage of ether or hydrolysis in a compound that falls in particular under formula I, in which R2 signifies the hydroxyl group, and in addition, if desired, a compound thus obtained, is transformed with an inorganic or organic acid, into a salt. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32206363A | 1963-11-07 | 1963-11-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES305739A1 true ES305739A1 (en) | 1965-04-16 |
Family
ID=23253254
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0305739A Expired ES305739A1 (en) | 1963-11-07 | 1964-11-06 | Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) |
| ES0305740A Expired ES305740A1 (en) | 1963-11-07 | 1964-11-06 | Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) |
| ES0305738A Expired ES305738A1 (en) | 1963-11-07 | 1964-11-06 | Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0305740A Expired ES305740A1 (en) | 1963-11-07 | 1964-11-06 | Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) |
| ES0305738A Expired ES305738A1 (en) | 1963-11-07 | 1964-11-06 | Procedure for the preparation of new 5-phenyl-6,7-benzomorphanes replaced. (Machine-translation by Google Translate, not legally binding) |
Country Status (3)
| Country | Link |
|---|---|
| AT (5) | AT254399B (en) |
| ES (3) | ES305739A1 (en) |
| FR (2) | FR4024M (en) |
-
1964
- 1964-11-06 ES ES0305739A patent/ES305739A1/en not_active Expired
- 1964-11-06 AT AT954965A patent/AT254399B/en active
- 1964-11-06 AT AT406865A patent/AT257055B/en active
- 1964-11-06 ES ES0305740A patent/ES305740A1/en not_active Expired
- 1964-11-06 ES ES0305738A patent/ES305738A1/en not_active Expired
- 1964-11-06 AT AT407065A patent/AT255033B/en active
- 1964-11-06 AT AT406965A patent/AT254398B/en active
- 1964-11-06 AT AT942864A patent/AT251201B/en active
-
1965
- 1965-02-05 FR FR4501A patent/FR4024M/fr not_active Expired
- 1965-02-05 FR FR4500A patent/FR4040M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES305740A1 (en) | 1965-04-16 |
| AT251201B (en) | 1966-12-27 |
| FR4040M (en) | 1966-03-28 |
| FR4024M (en) | 1966-03-21 |
| AT257055B (en) | 1967-09-25 |
| AT254398B (en) | 1967-05-26 |
| AT254399B (en) | 1967-05-26 |
| AT255033B (en) | 1967-06-26 |
| ES305738A1 (en) | 1965-05-01 |
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