ES385774A1 - Procedure for the preparation of new 2- (5-nitro-2- furil) -the (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new 2- (5-nitro-2- furil) -the (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES385774A1
ES385774A1 ES385774A ES385774A ES385774A1 ES 385774 A1 ES385774 A1 ES 385774A1 ES 385774 A ES385774 A ES 385774A ES 385774 A ES385774 A ES 385774A ES 385774 A1 ES385774 A1 ES 385774A1
Authority
ES
Spain
Prior art keywords
pyrimidines
nitro
translation
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES385774A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES385774A1 publication Critical patent/ES385774A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Procedure for the preparation of new 2- (5-nitro-2-furyl) -thiene [3,2-d] pyrimidines of the general formula I **(See formula)** in which the radical R means a lower aliphatic acylamino group optionally substituted by 1 or 2 chlorine atoms and R1 represents a hydrogen atom or the methyl group, and of its salts by addition of acid with organic or inorganic acids, characterized in that a compound of the general formula II is acylated **(See formula)** wherein R1 is as initially defined, and if desired, the compounds thus obtained are then transformed by organic or inorganic acids into their acid addition salts. (Machine-translation by Google Translate, not legally binding)
ES385774A 1970-10-16 1970-11-21 Procedure for the preparation of new 2- (5-nitro-2- furil) -the (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding) Expired ES385774A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702050814 DE2050814A1 (en) 1970-10-16 1970-10-16 New process for the preparation of 2- (5-nitro-2-furyl) -thieno square bracket on 3.2-square bracket to pyrimidines

Publications (1)

Publication Number Publication Date
ES385774A1 true ES385774A1 (en) 1973-11-16

Family

ID=5785287

Family Applications (3)

Application Number Title Priority Date Filing Date
ES385773A Expired ES385773A1 (en) 1970-10-16 1970-11-21 Procedure for the preparation of new 2- (5-nitro-2- furil) - tieno (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)
ES385774A Expired ES385774A1 (en) 1970-10-16 1970-11-21 Procedure for the preparation of new 2- (5-nitro-2- furil) -the (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)
ES385772A Expired ES385772A1 (en) 1970-10-16 1970-11-21 Procedure for the preparation of new 2- (5-nitro-2- furil) -the (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES385773A Expired ES385773A1 (en) 1970-10-16 1970-11-21 Procedure for the preparation of new 2- (5-nitro-2- furil) - tieno (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES385772A Expired ES385772A1 (en) 1970-10-16 1970-11-21 Procedure for the preparation of new 2- (5-nitro-2- furil) -the (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
DE (1) DE2050814A1 (en)
ES (3) ES385773A1 (en)
RO (2) RO58536A (en)
SU (2) SU419028A3 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101507182B1 (en) * 2006-12-07 2015-03-30 제넨테크, 인크. Phosphoinositide 3-kinase inhibitor compounds and methods of use
ES2544082T3 (en) 2006-12-07 2015-08-27 F. Hoffmann-La Roche Ag Phosphoinositide 3-kinase inhibitor compounds and methods of use
SG11201804901WA (en) 2015-12-22 2018-07-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
EA201992780A1 (en) 2017-06-21 2020-06-02 ШАЙ ТЕРАПЬЮТИКС ЭлЭлСи COMPOUNDS THAT INTERACT WITH THE RAS SUPERFAMILY FOR TREATMENT OF CANCER, INFLAMMATORY DISEASES, RAS OPATIAS AND FIBROUS DISEASE

Also Published As

Publication number Publication date
RO58553A (en) 1975-09-15
DE2050814A1 (en) 1972-04-20
ES385773A1 (en) 1973-11-16
RO58536A (en) 1975-10-15
SU419028A3 (en) 1974-03-05
SU425393A3 (en) 1974-04-25
ES385772A1 (en) 1973-11-16

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