ES369805A1 - Procedure for the preparation of new indolinas basically replaced. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new indolinas basically replaced. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES369805A1 ES369805A1 ES369805A ES369805A ES369805A1 ES 369805 A1 ES369805 A1 ES 369805A1 ES 369805 A ES369805 A ES 369805A ES 369805 A ES369805 A ES 369805A ES 369805 A1 ES369805 A1 ES 369805A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- radicals
- radical
- alcohol
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procedure for the preparation of new basically substituted indolines of the general formula I **(See formula)** wherein R1 signifies an alcohol radical with 1 to 5 carbon atoms; R2 and R3 which may be the same or different, mean hydrogen or chlorine atoms, alcohol radicals or lower alkoxy with 1 to 2 carbon atoms; R4 and R5, which may be the same or different, mean alcohol radicals with 1 to 5 carbon atoms, which may optionally be substituted by a cycloalcohyl radical; alkenyl radicals with 3 to 5 carbon atoms, or cycloalkoxy radicals with 5 to 7 carbon atoms, R4 and R5 may also form, together with the nitrogen atom located between them, a saturated 5-or 6-membered ring, monocyclic, monocyclic, which may optionally be further interrupted by an oxygen atom or by another nitrogen atom and/or may be substituted by an alcohol radical with 1 to 3 carbon atoms or by a phenyl radical, A has the meaning of an aliphatic hydrocarbon radical bivalent with 2 to 4 carbon atoms and n means the numbers 1 or 2, as well as their acid addition salts with organic or inorganic acids, characterized in that a pseudoindole of the general formula II is reduced **(See formula)** wherein the radicals R1 to R5, A and n are, as defined above, and the stereoisomer mixtures obtained are optionally separated, and/or if desired, the compounds obtained are transformed into their salts by addition of acid. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19681795034 DE1795034C3 (en) | 1968-07-31 | Racemic cis-3- (2-dimethylamino-1-propyl) -2-methyl-3-phenylindoline, its salts, process for their preparation and pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES369805A1 true ES369805A1 (en) | 1971-07-16 |
Family
ID=5708032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES369805A Expired ES369805A1 (en) | 1968-07-31 | 1969-07-23 | Procedure for the preparation of new indolinas basically replaced. (Machine-translation by Google Translate, not legally binding) |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS4943960B1 (en) |
| AT (1) | AT285598B (en) |
| CH (1) | CH513851A (en) |
| ES (1) | ES369805A1 (en) |
| NL (1) | NL162069C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS514065U (en) * | 1974-06-26 | 1976-01-13 |
-
1969
- 1969-07-23 ES ES369805A patent/ES369805A1/en not_active Expired
- 1969-07-30 JP JP5971869A patent/JPS4943960B1/ja active Pending
- 1969-07-30 AT AT735269A patent/AT285598B/en not_active IP Right Cessation
- 1969-07-31 CH CH1169569A patent/CH513851A/en not_active IP Right Cessation
- 1969-07-31 NL NL6911685A patent/NL162069C/en active
Also Published As
| Publication number | Publication date |
|---|---|
| AT285598B (en) | 1970-11-10 |
| NL162069B (en) | 1979-11-15 |
| NL6911685A (en) | 1970-02-03 |
| DE1795034A1 (en) | 1972-01-27 |
| NL162069C (en) | 1980-04-15 |
| CH513851A (en) | 1971-10-15 |
| JPS4943960B1 (en) | 1974-11-25 |
| DE1795034B2 (en) | 1977-06-23 |
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