ES2989969T3 - Uso novedoso de mononucleótido de nicotinamida (NMN) y ribósido de nicotinamida (NR) - Google Patents
Uso novedoso de mononucleótido de nicotinamida (NMN) y ribósido de nicotinamida (NR) Download PDFInfo
- Publication number
- ES2989969T3 ES2989969T3 ES20832373T ES20832373T ES2989969T3 ES 2989969 T3 ES2989969 T3 ES 2989969T3 ES 20832373 T ES20832373 T ES 20832373T ES 20832373 T ES20832373 T ES 20832373T ES 2989969 T3 ES2989969 T3 ES 2989969T3
- Authority
- ES
- Spain
- Prior art keywords
- meibomian gland
- composition
- nmn
- present disclosure
- nicotinamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019117642 | 2019-06-25 | ||
| PCT/JP2020/024916 WO2020262497A1 (ja) | 2019-06-25 | 2020-06-24 | ニコチンアミドモノヌクレオチド（ｎｍｎ）およびニコチンアミドリボシド（ｎｒ）の新規用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2989969T3 true ES2989969T3 (es) | 2024-11-28 |
Family
ID=74060627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES20832373T Active ES2989969T3 (es) | 2019-06-25 | 2020-06-24 | Uso novedoso de mononucleótido de nicotinamida (NMN) y ribósido de nicotinamida (NR) |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220370484A1 (https=) |
| EP (1) | EP3991795B1 (https=) |
| JP (1) | JP7572007B2 (https=) |
| CN (1) | CN114007693B (https=) |
| ES (1) | ES2989969T3 (https=) |
| PL (1) | PL3991795T3 (https=) |
| WO (1) | WO2020262497A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119792334A (zh) * | 2025-02-25 | 2025-04-11 | 中国农业大学 | 组合物及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2609549A1 (en) * | 2005-05-25 | 2006-11-30 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| EP2968306B1 (en) * | 2013-03-15 | 2023-06-07 | Washington University | Administration of nicotinamide mononucleotide in the treatment of dry eye |
| JP2018100222A (ja) * | 2015-04-20 | 2018-06-28 | 学校法人慶應義塾 | 角膜損傷の治療剤、改善剤または予防剤 |
| CA3288232A1 (en) * | 2015-10-23 | 2025-11-29 | Jackson Lab | Nicotinamide is used in the treatment and prevention of neurodegenerative eye disorders (for example, glaucoma). |
| US20170326161A1 (en) * | 2015-12-10 | 2017-11-16 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical formulations for treating skin disorders and methods for fabricating and using thereof |
| WO2018052019A1 (ja) * | 2016-09-13 | 2018-03-22 | めぐみ 田中 | 視覚機能改善剤及び視覚機能の改善方法 |
| KR20210153027A (ko) * | 2018-09-14 | 2021-12-16 | 메구미 타나카 | 노화방지제 및 노화방지방법 |
| JP6831407B2 (ja) | 2019-02-22 | 2021-02-17 | 能美防災株式会社 | 火災受信機 |
-
2020
- 2020-06-24 CN CN202080047245.3A patent/CN114007693B/zh active Active
- 2020-06-24 US US17/621,114 patent/US20220370484A1/en active Pending
- 2020-06-24 WO PCT/JP2020/024916 patent/WO2020262497A1/ja not_active Ceased
- 2020-06-24 JP JP2021527709A patent/JP7572007B2/ja active Active
- 2020-06-24 PL PL20832373.3T patent/PL3991795T3/pl unknown
- 2020-06-24 EP EP20832373.3A patent/EP3991795B1/en active Active
- 2020-06-24 ES ES20832373T patent/ES2989969T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3991795A1 (en) | 2022-05-04 |
| US20220370484A1 (en) | 2022-11-24 |
| WO2020262497A1 (ja) | 2020-12-30 |
| CN114007693A (zh) | 2022-02-01 |
| EP3991795B1 (en) | 2024-09-11 |
| JPWO2020262497A1 (https=) | 2020-12-30 |
| JP7572007B2 (ja) | 2024-10-23 |
| CN114007693B (zh) | 2024-07-12 |
| EP3991795A4 (en) | 2023-07-19 |
| PL3991795T3 (pl) | 2025-01-13 |
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