ES2989969T3 - Uso novedoso de mononucleótido de nicotinamida (NMN) y ribósido de nicotinamida (NR) - Google Patents

Uso novedoso de mononucleótido de nicotinamida (NMN) y ribósido de nicotinamida (NR) Download PDF

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Publication number
ES2989969T3
ES2989969T3 ES20832373T ES20832373T ES2989969T3 ES 2989969 T3 ES2989969 T3 ES 2989969T3 ES 20832373 T ES20832373 T ES 20832373T ES 20832373 T ES20832373 T ES 20832373T ES 2989969 T3 ES2989969 T3 ES 2989969T3
Authority
ES
Spain
Prior art keywords
meibomian gland
composition
nmn
present disclosure
nicotinamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES20832373T
Other languages
English (en)
Spanish (es)
Inventor
Masao Doi
Takeshi Nakajima
Mamiko Machida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Kyoto University NUC
Original Assignee
Senju Pharmaceutical Co Ltd
Kyoto University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd, Kyoto University NUC filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2989969T3 publication Critical patent/ES2989969T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ES20832373T 2019-06-25 2020-06-24 Uso novedoso de mononucleótido de nicotinamida (NMN) y ribósido de nicotinamida (NR) Active ES2989969T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019117642 2019-06-25
PCT/JP2020/024916 WO2020262497A1 (ja) 2019-06-25 2020-06-24 ニコチンアミドモノヌクレオチド(nmn)およびニコチンアミドリボシド(nr)の新規用途

Publications (1)

Publication Number Publication Date
ES2989969T3 true ES2989969T3 (es) 2024-11-28

Family

ID=74060627

Family Applications (1)

Application Number Title Priority Date Filing Date
ES20832373T Active ES2989969T3 (es) 2019-06-25 2020-06-24 Uso novedoso de mononucleótido de nicotinamida (NMN) y ribósido de nicotinamida (NR)

Country Status (7)

Country Link
US (1) US20220370484A1 (https=)
EP (1) EP3991795B1 (https=)
JP (1) JP7572007B2 (https=)
CN (1) CN114007693B (https=)
ES (1) ES2989969T3 (https=)
PL (1) PL3991795T3 (https=)
WO (1) WO2020262497A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119792334A (zh) * 2025-02-25 2025-04-11 中国农业大学 组合物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006127987A2 (en) * 2005-05-25 2006-11-30 Sirtris Pharmaceuticals, Inc. Treatment of eye disorders with sirtuin modulators
PL2968306T3 (pl) * 2013-03-15 2024-01-29 Washington University Podawanie mononukleotydu nikotynamidu do leczenia zespołu suchego oka
JP2018100222A (ja) * 2015-04-20 2018-06-28 学校法人慶應義塾 角膜損傷の治療剤、改善剤または予防剤
EP3364973A1 (en) * 2015-10-23 2018-08-29 The Jackson Laboratory Nicotinamide for use in the treatment and prevention of ocular neurodegenerative disorder (e.g. glaucoma)
US20170326161A1 (en) * 2015-12-10 2017-11-16 Imprimis Pharmaceuticals, Inc. Pharmaceutical formulations for treating skin disorders and methods for fabricating and using thereof
US10898738B2 (en) * 2016-09-13 2021-01-26 Megumi Tanaka Visual function printing agent, and method for improving visual functions
EP3850954A4 (en) * 2018-09-14 2022-06-08 Megumi Tanaka ANTI-AGEING AGENTS AND PROCESSES
JP6831407B2 (ja) 2019-02-22 2021-02-17 能美防災株式会社 火災受信機

Also Published As

Publication number Publication date
JP7572007B2 (ja) 2024-10-23
EP3991795A1 (en) 2022-05-04
EP3991795A4 (en) 2023-07-19
CN114007693B (zh) 2024-07-12
EP3991795B1 (en) 2024-09-11
PL3991795T3 (pl) 2025-01-13
CN114007693A (zh) 2022-02-01
US20220370484A1 (en) 2022-11-24
JPWO2020262497A1 (https=) 2020-12-30
WO2020262497A1 (ja) 2020-12-30

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