ES2988280T3 - Formulaciones y métodos relacionados para el tratamiento de enfermedades de la superficie ocular - Google Patents

Formulaciones y métodos relacionados para el tratamiento de enfermedades de la superficie ocular Download PDF

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Publication number
ES2988280T3
ES2988280T3 ES17868628T ES17868628T ES2988280T3 ES 2988280 T3 ES2988280 T3 ES 2988280T3 ES 17868628 T ES17868628 T ES 17868628T ES 17868628 T ES17868628 T ES 17868628T ES 2988280 T3 ES2988280 T3 ES 2988280T3
Authority
ES
Spain
Prior art keywords
formulation
ambroxol
use according
formulations
ocular surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17868628T
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English (en)
Spanish (es)
Inventor
Mingwu Wang
Cindy A Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neuvision Dev LLC
Original Assignee
Neuvision Dev LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuvision Dev LLC filed Critical Neuvision Dev LLC
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Publication of ES2988280T3 publication Critical patent/ES2988280T3/es
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES17868628T 2016-11-14 2017-11-10 Formulaciones y métodos relacionados para el tratamiento de enfermedades de la superficie ocular Active ES2988280T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662421822P 2016-11-14 2016-11-14
US201762463717P 2017-02-26 2017-02-26
PCT/US2017/061108 WO2018089797A1 (en) 2016-11-14 2017-11-10 Formulations for the treatment of ocular surface diseases and related methods

Publications (1)

Publication Number Publication Date
ES2988280T3 true ES2988280T3 (es) 2024-11-19

Family

ID=62107036

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17868628T Active ES2988280T3 (es) 2016-11-14 2017-11-10 Formulaciones y métodos relacionados para el tratamiento de enfermedades de la superficie ocular

Country Status (9)

Country Link
US (5) US10265280B2 (enExample)
EP (1) EP3538083B1 (enExample)
JP (1) JP6871400B2 (enExample)
KR (1) KR102116303B1 (enExample)
CN (2) CN109982692A (enExample)
AU (1) AU2017357755B2 (enExample)
CA (1) CA3043327C (enExample)
ES (1) ES2988280T3 (enExample)
WO (1) WO2018089797A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108969511A (zh) * 2018-07-12 2018-12-11 图桑医疗科技（深圳）有限公司 溴已新及其衍生物在治疗和预防眼表疾病上的应用
US11326176B2 (en) 2019-11-22 2022-05-10 Mozza Foods, Inc. Recombinant micelle and method of in vivo assembly
US12359212B2 (en) 2019-11-22 2025-07-15 Mozza Foods, Inc. Recombinant micelle and method of in vivo assembly
CN112915090A (zh) * 2019-12-07 2021-06-08 王明武 用于治疗眼表疾病的一类化合物及其相关制剂和应用方法
AU2023277608A1 (en) * 2022-05-21 2024-11-28 Neuvision Development Llc Topical ocular administration of ambroxol for ocular pain

Family Cites Families (37)

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AU574360B2 (en) 1983-05-13 1988-07-07 Reichert, D. Antisnoring agent
DE3610997A1 (de) 1986-04-02 1987-10-15 Krewel Werke Gmbh Ambroxol-nasenspray
DE3731528A1 (de) * 1987-09-18 1989-04-13 Krewel Werke Gmbh Verwendung von trans-4- ((2-amino-3,5-dibrom-benzyl)-amino) -cyclohexanol zur lokalen behandlung von erkrankungen des auges
JPH08509725A (ja) 1993-04-30 1996-10-15 ザ、プロクター、エンド、ギャンブル、カンパニー コートされた医薬組成物
US5458879A (en) 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
IT1303671B1 (it) 1998-07-28 2001-02-23 Nicox Sa Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio
AU770803B2 (en) 1998-12-23 2004-03-04 Idea Ag Improved formulation for topical non-invasive application in vivo
DE19933148A1 (de) 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
US7179849B2 (en) 1999-12-15 2007-02-20 C. R. Bard, Inc. Antimicrobial compositions containing colloids of oligodynamic metals
CA2373171A1 (en) 2000-03-07 2001-09-13 Teijin Limited Stretch plaster
US20030216423A1 (en) 2000-05-24 2003-11-20 Sergio Ulloa Stable liquid and solid formulations
ITRM20010438A1 (it) * 2001-07-23 2003-01-23 Farmigea Spa Preparato oftalmico a base di n-acetilcisteina per il trattamento della sindrome dell'occhio secco.
DE10140320A1 (de) 2001-08-16 2003-03-06 Udo Zirfas Potenzfördernder und vitaltonisierender Wirkstoff
DE10203104A1 (de) 2002-01-25 2003-08-07 Boehringer Ingelheim Pharma Ambroxol für die Behandlung chronischer Schmerzen
US20030171391A1 (en) 2002-01-25 2003-09-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of chronic pain
DE10208313A1 (de) 2002-02-27 2003-09-11 Boehringer Ingelheim Pharma Ambroxol für die Behandlung von schmerzhaften Zuständen im Mund und Rachenraum
US20030166732A1 (en) 2002-02-27 2003-09-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
JP2004175749A (ja) * 2002-11-28 2004-06-24 Senju Pharmaceut Co Ltd ドライアイおよびドライアイを伴う疾病の治療剤
DE10332487A1 (de) 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung von chronisch nozizeptiven Schmerzen
DE10332486A1 (de) 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung akuter Schmerzen
DE10332473A1 (de) 2003-07-16 2005-02-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung von Epilepsie
AU2003904192A0 (en) * 2003-08-11 2003-08-21 Adelaide Research and Innovaiton Pty Ltd Method for inhibiting bacterial colonisation
KR20050036166A (ko) * 2003-10-15 2005-04-20 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 인두내 염증 치료용 암브록솔
US9016221B2 (en) 2004-02-17 2015-04-28 University Of Florida Research Foundation, Inc. Surface topographies for non-toxic bioadhesion control
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US20070014833A1 (en) * 2005-03-30 2007-01-18 Sirtris Pharmaceuticals, Inc. Treatment of eye disorders with sirtuin modulators
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JP5337405B2 (ja) 2007-09-17 2013-11-06 ザ・ホスピタル・フォー・シック・チルドレン ゴーシェ病の治療方法
GB0801876D0 (en) 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
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EP2793872B1 (en) 2011-12-22 2021-03-10 Centogene IP GmbH Combination of a compound having the ability to rearrange a lysosomal enzyme and ambroxol and/or a derivative of ambroxol
CN102670607A (zh) 2012-05-28 2012-09-19 海南卫康制药(潜山)有限公司 复方盐酸氨溴索组合物及其制备方法
US20140235554A1 (en) * 2013-02-12 2014-08-21 Brian Lawrence Ophthalmic formulation derived from silk protein
HU231191B1 (hu) 2013-04-15 2021-08-30 Szegedi Tudományegyetem Izotóp tartalmú morfin molekulák
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Also Published As

Publication number Publication date
CN115607531A (zh) 2023-01-17
US20210046022A1 (en) 2021-02-18
JP6871400B2 (ja) 2021-05-12
KR102116303B1 (ko) 2020-05-29
AU2017357755B2 (en) 2019-06-13
WO2018089797A1 (en) 2018-05-17
EP3538083B1 (en) 2024-07-10
US20220378723A1 (en) 2022-12-01
US20180133173A1 (en) 2018-05-17
CA3043327A1 (en) 2018-05-17
AU2017357755A1 (en) 2019-05-30
US20190209496A1 (en) 2019-07-11
CN109982692A (zh) 2019-07-05
US10265280B2 (en) 2019-04-23
EP3538083A4 (en) 2020-05-27
JP2019534335A (ja) 2019-11-28
US20240374540A1 (en) 2024-11-14
KR20190085038A (ko) 2019-07-17
CA3043327C (en) 2020-08-11
EP3538083A1 (en) 2019-09-18

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