ES2975662T3 - Biomarcadores y métodos de uso para la lesión pulmonar inducida por radiación - Google Patents
Biomarcadores y métodos de uso para la lesión pulmonar inducida por radiación Download PDFInfo
- Publication number
- ES2975662T3 ES2975662T3 ES19802268T ES19802268T ES2975662T3 ES 2975662 T3 ES2975662 T3 ES 2975662T3 ES 19802268 T ES19802268 T ES 19802268T ES 19802268 T ES19802268 T ES 19802268T ES 2975662 T3 ES2975662 T3 ES 2975662T3
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- Spain
- Prior art keywords
- nampt
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- rili
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/02012—Nicotinamide phosphoribosyltransferase (2.4.2.12), i.e. visfatin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/12—Pulmonary diseases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/40—Disorders due to exposure to physical agents, e.g. heat disorders, motion sickness, radiation injuries, altitude sickness, decompression illness
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862753802P | 2018-10-31 | 2018-10-31 | |
| US201962896483P | 2019-09-05 | 2019-09-05 | |
| PCT/IB2019/059379 WO2020089841A1 (en) | 2018-10-31 | 2019-10-31 | Biomarkers and methods of use for radiation-induced lung injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2975662T3 true ES2975662T3 (es) | 2024-07-11 |
Family
ID=68542675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19802268T Active ES2975662T3 (es) | 2018-10-31 | 2019-10-31 | Biomarcadores y métodos de uso para la lesión pulmonar inducida por radiación |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11733242B2 (enExample) |
| EP (2) | EP3874273B1 (enExample) |
| JP (1) | JP7534293B2 (enExample) |
| CN (1) | CN113614535B (enExample) |
| AU (1) | AU2019371161A1 (enExample) |
| CA (1) | CA3117112A1 (enExample) |
| ES (1) | ES2975662T3 (enExample) |
| WO (1) | WO2020089841A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220403412A1 (en) * | 2021-06-11 | 2022-12-22 | Hui JING | Baculovirus Of Recombinant Superoxide Dismutase Gene, Preparation And Application Thereof |
| CN114578058A (zh) * | 2022-02-09 | 2022-06-03 | 中国人民解放军军事科学院军事医学研究院 | 一种放射损伤标志物bpifa2的应用及其相关试剂盒及试剂 |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4415723A (en) | 1982-03-19 | 1983-11-15 | General Electric Company | Randomly branched aromatic polycarbonate from triphenol |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| ATE88761T1 (de) | 1986-01-10 | 1993-05-15 | Amoco Corp | Kompetitiver homogener test. |
| IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| ATE92538T1 (de) | 1988-01-21 | 1993-08-15 | Genentech Inc | Verstaerkung und nachweis von nukleinsaeuresequenzen. |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5932413A (en) | 1988-04-01 | 1999-08-03 | Celebuski; Joseph Eugene | DNA probe assay using neutrally charged probe strands |
| US5187260A (en) | 1988-09-06 | 1993-02-16 | Sharifa Karali | Process for the preparation of a high purity protamine-DNA complex and process for use of same |
| US5856092A (en) | 1989-02-13 | 1999-01-05 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
| US5075212A (en) | 1989-03-27 | 1991-12-24 | University Of Patents, Inc. | Methods of detecting picornaviruses in biological fluids and tissues |
| US5849481A (en) | 1990-07-27 | 1998-12-15 | Chiron Corporation | Nucleic acid hybridization assays employing large comb-type branched polynucleotides |
| US5645987A (en) | 1990-09-21 | 1997-07-08 | Amgen Inc. | Enzymatic synthesis of oligonucleotides |
| US5846717A (en) | 1996-01-24 | 1998-12-08 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
| US5849486A (en) | 1993-11-01 | 1998-12-15 | Nanogen, Inc. | Methods for hybridization analysis utilizing electrically controlled hybridization |
| US5846708A (en) | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
| FR2685346B1 (fr) | 1991-12-18 | 1994-02-11 | Cis Bio International | Procede de preparation d'arn double-brin, et ses applications. |
| JP3633932B2 (ja) | 1992-04-01 | 2005-03-30 | ザ ジョーンズ ホプキンズ ユニバーシティー スクール オブ メディシン | 糞便試料から単離した哺乳類の核酸を検出する方法、およびその検出用試薬 |
| US5843640A (en) | 1992-06-19 | 1998-12-01 | Northwestern University | Method of simultaneously detecting amplified nucleic acid sequences and cellular antigens in cells |
| US5861244A (en) | 1992-10-29 | 1999-01-19 | Profile Diagnostic Sciences, Inc. | Genetic sequence assay using DNA triple strand formation |
| US5658751A (en) | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
| US5279721A (en) | 1993-04-22 | 1994-01-18 | Peter Schmid | Apparatus and method for an automated electrophoresis system |
| GB9311386D0 (en) | 1993-06-02 | 1993-07-21 | Pna Diagnostics As | Nucleic acid analogue assay procedures |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| GB2284208A (en) | 1993-11-25 | 1995-05-31 | Pna Diagnostics As | Nucleic acid analogues with a chelating functionality for metal ions |
| DE69432919T2 (de) | 1993-12-28 | 2004-05-27 | Tanabe Seiyaku Co., Ltd. | Verfahren für den Nachweis spezifischer Polynukleotiden |
| US5599668A (en) | 1994-09-22 | 1997-02-04 | Abbott Laboratories | Light scattering optical waveguide method for detecting specific binding events |
| DE69535240T2 (de) | 1994-10-28 | 2007-06-06 | Gen-Probe Inc., San Diego | Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen |
| US5889136A (en) | 1995-06-09 | 1999-03-30 | The Regents Of The University Of Colorado | Orthoester protecting groups in RNA synthesis |
| US5929227A (en) | 1995-07-12 | 1999-07-27 | The Regents Of The University Of California | Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores |
| US5916779A (en) | 1995-09-21 | 1999-06-29 | Becton, Dickinson And Company | Strand displacement amplification of RNA targets |
| US5866331A (en) | 1995-10-20 | 1999-02-02 | University Of Massachusetts | Single molecule detection by in situ hybridization |
| US5851772A (en) | 1996-01-29 | 1998-12-22 | University Of Chicago | Microchip method for the enrichment of specific DNA sequences |
| US5912124A (en) | 1996-06-14 | 1999-06-15 | Sarnoff Corporation | Padlock probe detection |
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| US20050143336A1 (en) | 2003-12-30 | 2005-06-30 | Board Of Regents, The University Of Texas System | Methods and compositions for improved non-viral gene therapy |
| US9409983B2 (en) | 2009-07-23 | 2016-08-09 | The Board Of Trustess Of The University Of Illinois | Methods and compositions involving PBEF inhibitors for lung inflammation conditions and diseases |
| WO2011109650A1 (en) | 2010-03-03 | 2011-09-09 | The Board Of Trustees Of The University Of Illinois | Method of treating acute lung injury using sphingosine 1 phosphate analoges or sphingosine 1 phosphate receptor agonists |
| CN103961691A (zh) * | 2013-02-03 | 2014-08-06 | 复旦大学 | 尼克酰胺磷酸核糖转移酶在制备神经保护药物中的用途 |
| ITTO20130356A1 (it) * | 2013-05-03 | 2014-11-04 | Uni Degli Studi Del Piemonte Orientale Ame | Inibitori di nicotinamide fosforibosil transferasi, relative composizioni, prodotti ed usi |
| JP6793451B2 (ja) | 2014-11-14 | 2020-12-02 | キヤノンメディカルシステムズ株式会社 | 被検細胞の細胞特性を評価するための遺伝子マーカー、方法、レポーターベクター、プライマーセットおよびアッセイキット、並びに細胞特性評価装置 |
| US20190023809A1 (en) | 2015-09-03 | 2019-01-24 | The Children's Mercy Hospital | Anti-nicotinamide phosphoribosyltransferase antibody genes and methods of use thereof |
| WO2018191747A1 (en) | 2017-04-14 | 2018-10-18 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating pulmonary arterial hypertension |
| CN110945128B (zh) | 2017-04-14 | 2023-11-03 | 代表亚利桑那大学的亚利桑那董事会 | 用于治疗肺纤维化的组合物和方法 |
| CA3147020A1 (en) | 2019-08-07 | 2021-02-11 | Joe G.N. Garcia | Anti-nampt antibodies and uses thereof |
| EP4010486A4 (en) | 2019-08-07 | 2023-11-01 | Arizona Board of Regents on behalf of the University of Arizona | MONONUCLEOTIDE POLYMORPHISMS AND THEIR USES |
| CA3188685A1 (en) | 2020-08-07 | 2022-02-10 | Joe G.N. Garcia | Single nucleotide polymorphisms and treatment of inflammatory conditions |
-
2019
- 2019-10-31 CN CN201980087173.2A patent/CN113614535B/zh active Active
- 2019-10-31 US US16/670,880 patent/US11733242B2/en active Active
- 2019-10-31 WO PCT/IB2019/059379 patent/WO2020089841A1/en not_active Ceased
- 2019-10-31 EP EP19802268.3A patent/EP3874273B1/en active Active
- 2019-10-31 JP JP2021523754A patent/JP7534293B2/ja active Active
- 2019-10-31 AU AU2019371161A patent/AU2019371161A1/en not_active Abandoned
- 2019-10-31 ES ES19802268T patent/ES2975662T3/es active Active
- 2019-10-31 CA CA3117112A patent/CA3117112A1/en active Pending
- 2019-10-31 EP EP24166259.2A patent/EP4439066A2/en not_active Withdrawn
-
2023
- 2023-08-21 US US18/453,286 patent/US20240085422A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3874273B1 (en) | 2024-03-27 |
| EP3874273A1 (en) | 2021-09-08 |
| JP2022509018A (ja) | 2022-01-20 |
| AU2019371161A1 (en) | 2021-06-17 |
| JP7534293B2 (ja) | 2024-08-14 |
| EP4439066A2 (en) | 2024-10-02 |
| CN113614535B (zh) | 2024-08-16 |
| US11733242B2 (en) | 2023-08-22 |
| WO2020089841A1 (en) | 2020-05-07 |
| CN113614535A (zh) | 2021-11-05 |
| US20240085422A1 (en) | 2024-03-14 |
| EP3874273C0 (en) | 2024-03-27 |
| CA3117112A1 (en) | 2020-05-07 |
| US20200132689A1 (en) | 2020-04-30 |
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