ES2973864T3 - Composiciones, métodos y/o kits que comprenden un dominio extracelular de CD38 recombinante humano - Google Patents

Composiciones, métodos y/o kits que comprenden un dominio extracelular de CD38 recombinante humano Download PDF

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Publication number
ES2973864T3
ES2973864T3 ES19184018T ES19184018T ES2973864T3 ES 2973864 T3 ES2973864 T3 ES 2973864T3 ES 19184018 T ES19184018 T ES 19184018T ES 19184018 T ES19184018 T ES 19184018T ES 2973864 T3 ES2973864 T3 ES 2973864T3
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Spain
Prior art keywords
cd38ecd
seq
tag
oligomerization
recombinant
Prior art date
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Active
Application number
ES19184018T
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English (en)
Spanish (es)
Inventor
Vincenzo Favaloro
Matteo Binda
John A Hall
Elizabeth Booth
Jody Berry
Peter Schwind
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Grifols Diagnostic Solutions Inc
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Grifols Diagnostic Solutions Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES19184018T 2017-08-10 2018-06-01 Composiciones, métodos y/o kits que comprenden un dominio extracelular de CD38 recombinante humano Active ES2973864T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762543788P 2017-08-10 2017-08-10

Publications (1)

Publication Number Publication Date
ES2973864T3 true ES2973864T3 (es) 2024-06-24

Family

ID=62846219

Family Applications (2)

Application Number Title Priority Date Filing Date
ES19184018T Active ES2973864T3 (es) 2017-08-10 2018-06-01 Composiciones, métodos y/o kits que comprenden un dominio extracelular de CD38 recombinante humano
ES18738376T Active ES2911243T3 (es) 2017-08-10 2018-06-01 Composiciones, procedimientos y/o kits que comprenden un dominio extracelular recombinante de cd38 humano

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES18738376T Active ES2911243T3 (es) 2017-08-10 2018-06-01 Composiciones, procedimientos y/o kits que comprenden un dominio extracelular recombinante de cd38 humano

Country Status (18)

Country Link
US (3) US11708418B2 (enExample)
EP (3) EP3587445B1 (enExample)
JP (3) JP6833851B2 (enExample)
KR (2) KR20240015159A (enExample)
CN (2) CN117820498A (enExample)
AR (1) AR112357A1 (enExample)
AU (2) AU2018313028B2 (enExample)
BR (1) BR112020002636A2 (enExample)
CA (1) CA3070789A1 (enExample)
EA (1) EA202090265A1 (enExample)
ES (2) ES2973864T3 (enExample)
HU (1) HUE065510T2 (enExample)
MX (3) MX2020001489A (enExample)
PL (1) PL3587445T3 (enExample)
PT (1) PT3587445T (enExample)
TW (1) TW201910349A (enExample)
UY (1) UY37757A (enExample)
WO (1) WO2019030581A1 (enExample)

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* Cited by examiner, † Cited by third party
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AR112357A1 (es) * 2017-08-10 2019-10-23 Grifols Diagnostic Solutions Inc Composiciones, procedimientos y/o kits que comprenden un dominio extracelular recombinante de cd38 humano
TW202000692A (zh) * 2018-02-20 2020-01-01 美商格里佛診斷方法股份有限公司 包含GpIbα的多肽和組合物、編碼該多肽的核酸及包含該多肽或該核酸的細胞
CN112048019B (zh) * 2019-06-06 2023-05-09 鲁南制药集团股份有限公司 抗人cd47单克隆抗体
AU2021338773A1 (en) * 2020-09-10 2023-05-25 Casi Pharmaceuticals, Inc. Methods of blood screening
CN112285361B (zh) * 2020-09-27 2023-12-05 中国人民解放军空军军医大学 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂
CN114917413B (zh) * 2022-06-14 2023-04-28 健诺维(成都)生物科技有限公司 一种负载重组多肽的羊膜及其制备方法
WO2024172419A1 (ko) * 2023-02-16 2024-08-22 주식회사 디엔티 Cd38 또는 이의 단편을 포함하는 자가면역질환 치료용 조성물
CN117723749B (zh) * 2024-02-07 2024-06-04 南昌大学 基于分子粘合剂的动态光散射免疫传感检测方法

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US6506551B1 (en) * 1999-10-08 2003-01-14 North Shore - Long Island Jewish Research Institute CD38 as a prognostic indicator in B cell chronic lymphocytic leukemia
AU2001273121A1 (en) * 2000-06-30 2002-01-14 Pharmacia And Upjohn Company Recombinant staphylococcus aureus peptide deformylase
EP1697520A2 (en) * 2003-12-22 2006-09-06 Xencor, Inc. Fc polypeptides with novel fc ligand binding sites
SI2511297T1 (sl) * 2004-02-06 2015-07-31 Morphosys Ag Proti -CD38 humana protitelesa in njihova uporaba
EP3753576A1 (en) * 2006-09-26 2020-12-23 Genmab A/S Combination treatment of cd38-expressing tumors
EP1914242A1 (en) * 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
CN103897063B (zh) * 2007-06-01 2017-04-12 马里兰大学巴尔的摩分校 免疫球蛋白恒定区Fc受体结合剂
EP2388270A3 (en) * 2007-10-11 2012-04-25 The Hospital For Sick Children Modulation of SIRPa - CD47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor
WO2010037837A2 (en) * 2008-10-01 2010-04-08 Micromet Ag Bispecific single chain antibodies with specificity for high molecular weight target antigens
SG194399A1 (en) * 2008-10-01 2013-11-29 Amgen Res Munich Gmbh Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxcd3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody
WO2010083253A2 (en) * 2009-01-14 2010-07-22 Viral Logic Systems Technology Corp. Cd47 related compositions and methods for treating immunological diseases and disorders
PL3053932T3 (pl) * 2010-02-19 2021-03-08 Xencor, Inc. Nowe immunoadhezyny CTLA4-IG
US20130029358A1 (en) * 2010-04-01 2013-01-31 Ludwig Institute For Cancer Research Ltd. Immunodominant mhc dr52b restricted ny-eso-1 epitopes, mhc class ii monomers and multimers, and uses thereof
SG188328A1 (en) * 2010-09-03 2013-04-30 Stem Centrx Inc Novel modulators and methods of use
EP2530089A1 (en) * 2011-06-03 2012-12-05 Bayer Pharma Aktiengesellschaft Neutralising prolactin receptor antibody Mat3 and its therapeutical use
EP2812443B1 (en) * 2012-02-06 2019-05-29 Inhibrx, Inc. Cd47 antibodies and methods of use thereof
ES2857900T3 (es) * 2012-04-27 2021-09-29 Novo Nordisk As Proteínas de unión a antígeno de ligando CD30 humano
SG11201408646VA (en) * 2012-07-06 2015-01-29 Genmab Bv Dimeric protein with triple mutations
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KR102252119B1 (ko) * 2014-06-18 2021-05-17 앨버트 아인슈타인 컬리지 오브 메디신 Syntac 폴리펩티드 및 이의 용도
MA40894A (fr) * 2014-11-04 2017-09-12 Glenmark Pharmaceuticals Sa Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production
WO2016081423A1 (en) * 2014-11-18 2016-05-26 Janssen Pharmaceutica Nv Cd47 antibodies, methods, and uses
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AR112357A1 (es) * 2017-08-10 2019-10-23 Grifols Diagnostic Solutions Inc Composiciones, procedimientos y/o kits que comprenden un dominio extracelular recombinante de cd38 humano

Also Published As

Publication number Publication date
EP4296680A2 (en) 2023-12-27
US20210198376A1 (en) 2021-07-01
JP2021088567A (ja) 2021-06-10
KR20240015159A (ko) 2024-02-02
AU2018313028A1 (en) 2020-02-20
KR20200035194A (ko) 2020-04-02
CA3070789A1 (en) 2019-02-14
MX2024005669A (es) 2024-05-30
EA202090265A1 (ru) 2020-06-05
WO2019030581A1 (en) 2019-02-14
HUE065510T2 (hu) 2024-05-28
PT3587445T (pt) 2024-03-14
JP6833851B2 (ja) 2021-02-24
AU2018313028B2 (en) 2023-05-25
BR112020002636A2 (pt) 2020-07-28
MX2024008109A (es) 2024-07-19
CN109790210A (zh) 2019-05-21
CN109790210B (zh) 2024-03-26
US11708418B2 (en) 2023-07-25
KR102631281B1 (ko) 2024-01-30
CN117820498A (zh) 2024-04-05
US20240132616A1 (en) 2024-04-25
US20240228651A9 (en) 2024-07-11
JP2019527533A (ja) 2019-10-03
UY37757A (es) 2018-11-30
ES2911243T3 (es) 2022-05-18
EP3464343A1 (en) 2019-04-10
EP3587445B1 (en) 2023-12-13
AU2023204121A1 (en) 2023-07-20
MX2020001489A (es) 2020-03-20
US20240092929A1 (en) 2024-03-21
EP3464343B1 (en) 2022-03-23
JP7289328B2 (ja) 2023-06-09
EP4296680A3 (en) 2024-03-20
EP3587445A1 (en) 2020-01-01
PL3587445T3 (pl) 2024-04-29
TW201910349A (zh) 2019-03-16
AR112357A1 (es) 2019-10-23
JP2023041802A (ja) 2023-03-24

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