ES2972934T3 - Combinación de sepetaprost y ripasudil para su uso en la profilaxis o tratamiento del glaucoma o hipertensión ocular - Google Patents
Combinación de sepetaprost y ripasudil para su uso en la profilaxis o tratamiento del glaucoma o hipertensión ocular Download PDFInfo
- Publication number
- ES2972934T3 ES2972934T3 ES18891292T ES18891292T ES2972934T3 ES 2972934 T3 ES2972934 T3 ES 2972934T3 ES 18891292 T ES18891292 T ES 18891292T ES 18891292 T ES18891292 T ES 18891292T ES 2972934 T3 ES2972934 T3 ES 2972934T3
- Authority
- ES
- Spain
- Prior art keywords
- sepetaprost
- ripasudil
- combination
- rho
- glaucoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017244847 | 2017-12-21 | ||
| JP2018180658 | 2018-09-26 | ||
| PCT/JP2018/046970 WO2019124488A1 (ja) | 2017-12-21 | 2018-12-20 | セペタプロストとＲｈｏキナーゼ阻害剤との組み合わせ医薬 |
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| ES2972934T3 true ES2972934T3 (es) | 2024-06-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| ES18891292T Active ES2972934T3 (es) | 2017-12-21 | 2018-12-20 | Combinación de sepetaprost y ripasudil para su uso en la profilaxis o tratamiento del glaucoma o hipertensión ocular |
| ES24153812T Active ES3041644T3 (en) | 2017-12-21 | 2018-12-20 | Combination of sepetaprost and netarsudil for use in the prophylaxis or treatment of glaucoma or ocular hypertension |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES24153812T Active ES3041644T3 (en) | 2017-12-21 | 2018-12-20 | Combination of sepetaprost and netarsudil for use in the prophylaxis or treatment of glaucoma or ocular hypertension |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11446273B2 (https=) |
| EP (2) | EP4338751B1 (https=) |
| JP (2) | JPWO2019124488A1 (https=) |
| KR (1) | KR102792934B1 (https=) |
| CN (1) | CN111479568A (https=) |
| CA (1) | CA3086457A1 (https=) |
| ES (2) | ES2972934T3 (https=) |
| TW (2) | TWI788484B (https=) |
| WO (1) | WO2019124488A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019124488A1 (ja) | 2017-12-21 | 2019-06-27 | 参天製薬株式会社 | セペタプロストとＲｈｏキナーゼ阻害剤との組み合わせ医薬 |
| CN111217834B (zh) * | 2020-02-21 | 2021-10-26 | 维眸生物科技（上海）有限公司 | Rock激酶抑制剂的硝基氧衍生物 |
| KR20230051199A (ko) * | 2020-08-13 | 2023-04-17 | 산텐 세이야꾸 가부시키가이샤 | 세페타프로스트를 함유하는 의약 제제 |
| TW202404569A (zh) | 2022-04-22 | 2024-02-01 | 日商參天製藥股份有限公司 | 含有賽佩普斯特(Sepetaprost)之眼科用組合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4952581A (en) | 1987-04-03 | 1990-08-28 | The Trustees Of Columbia University In The City Of New York | Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure |
| DE3871596T3 (de) | 1987-04-03 | 2000-09-07 | Pharmacia & Upjohn Ab, Stockholm | Anwendung eines Prostaglandins in Mischung mit einem adrenergischen Blocker zur Verminderung des Augen-Innendruckes. |
| ATE289815T1 (de) | 1995-12-21 | 2005-03-15 | Alcon Lab Inc | Verwendung von substituierten isochinolinsulfonyl-verbindungen zur herstellung eines medikaments für die behandlung von glaukom und okularer ischämie |
| BR9711154A (pt) | 1996-08-12 | 1999-08-17 | Yoshitomi Pharmaceutical | Agente farmac-utico contendo inibidor cinase rho |
| JP4212149B2 (ja) | 1998-06-11 | 2009-01-21 | 株式会社デ・ウエスタン・セラピテクス研究所 | 医薬 |
| CA2307285C (en) | 1998-08-17 | 2009-03-31 | Senju Pharmaceutical Co., Ltd. | Agent for prophylaxis and treatment of glaucoma |
| US7217722B2 (en) | 2000-02-01 | 2007-05-15 | Kirin Beer Kabushiki Kaisha | Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same |
| JP4342704B2 (ja) | 2000-07-21 | 2009-10-14 | 富士フイルム株式会社 | 液晶分子の配向方法 |
| US20030018079A1 (en) | 2000-11-13 | 2003-01-23 | Richardson Helene | Treatment |
| PE20020958A1 (es) | 2001-03-23 | 2002-11-14 | Bayer Corp | Inhibidores de la rho-quinasa |
| UY27224A1 (es) | 2001-03-23 | 2002-10-31 | Bayer Corp | Inhibidores de la rho-quinasa |
| WO2002100833A1 (en) | 2001-06-12 | 2002-12-19 | Sumitomo Pharmaceuticals Company, Limited | Rho KINASE INHIBITORS |
| JP4017921B2 (ja) | 2002-06-12 | 2007-12-05 | 高砂熱学工業株式会社 | 暖房室内の空気循環装置 |
| JP4128038B2 (ja) | 2002-07-10 | 2008-07-30 | 富士フイルム株式会社 | 電子ペーパー |
| JP4482726B2 (ja) | 2002-08-29 | 2010-06-16 | 参天製薬株式会社 | Ｒｈｏキナーゼ阻害剤とプロスタグランジン類からなる緑内障治療剤 |
| AU2003257588A1 (en) | 2002-08-29 | 2004-03-19 | Santen Pharmaceutical Co., Ltd. | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND PROSTAGLANDINS |
| AU2003280812A1 (en) | 2002-11-18 | 2004-06-15 | Santen Pharmaceutical Co., Ltd. | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND Beta-BLOCKER |
| TWI367098B (en) | 2004-12-23 | 2012-07-01 | Kowa Co | Treating agent for glaucoma |
| EP1792622A1 (en) * | 2005-11-11 | 2007-06-06 | GPC Biotech AG | Anti-proliferative combination therapy comprising a platinum-based chemotherapeutic agent and EGFR inhibitors or pyrimidine analogues |
| EP2127638A1 (en) * | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| JP2011530511A (ja) * | 2008-08-05 | 2011-12-22 | メルク・シャープ・エンド・ドーム・コーポレイション | 治療用化合物 |
| JP2010113957A (ja) | 2008-11-06 | 2010-05-20 | Ntt Docomo Inc | コネクタ |
| PT2415763E (pt) | 2009-03-30 | 2016-03-30 | Ube Industries | Composição farmacêutica para tratamento ou prevenção do glaucoma |
| EP3828172A1 (en) | 2009-05-01 | 2021-06-02 | Aerie Pharmaceuticals, Inc. | Dual mechanism inhibitors for the treatment of disease |
| JP2011013651A (ja) | 2009-07-03 | 2011-01-20 | Mitsumasa Maeda | フレキシブルディスプレイのれん |
| RU2540330C2 (ru) | 2009-07-28 | 2015-02-10 | Оно Фармасьютикал Ко., Лтд. | Бициклическое соединение и его применение для медицинских целей |
| JP5835236B2 (ja) | 2011-01-27 | 2015-12-24 | 小野薬品工業株式会社 | 二環式化合物およびその医薬用途 |
| ES2684351T3 (es) * | 2011-02-04 | 2018-10-02 | Kowa Co., Ltd. | Terapia farmacológica para prevenir o tratar glaucoma |
| WO2019124488A1 (ja) | 2017-12-21 | 2019-06-27 | 参天製薬株式会社 | セペタプロストとＲｈｏキナーゼ阻害剤との組み合わせ医薬 |
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- 2018-12-20 US US16/955,857 patent/US11446273B2/en active Active
- 2018-12-20 TW TW107146097A patent/TWI788484B/zh active
- 2018-12-20 CN CN201880081551.1A patent/CN111479568A/zh active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2019124488A1 (ja) | 2019-06-27 |
| EP4338751A2 (en) | 2024-03-20 |
| US11446273B2 (en) | 2022-09-20 |
| TW201927298A (zh) | 2019-07-16 |
| EP3730138A1 (en) | 2020-10-28 |
| EP3730138A4 (en) | 2021-08-25 |
| US20220387372A1 (en) | 2022-12-08 |
| CA3086457A1 (en) | 2019-06-27 |
| US20200316009A1 (en) | 2020-10-08 |
| EP4338751C0 (en) | 2025-09-03 |
| TWI833535B (zh) | 2024-02-21 |
| JPWO2019124488A1 (ja) | 2020-12-17 |
| KR20200103042A (ko) | 2020-09-01 |
| ES3041644T3 (en) | 2025-11-13 |
| EP4338751B1 (en) | 2025-09-03 |
| EP4338751A3 (en) | 2024-05-22 |
| EP3730138B1 (en) | 2024-02-14 |
| CN111479568A (zh) | 2020-07-31 |
| KR102792934B1 (ko) | 2025-04-07 |
| US12201602B2 (en) | 2025-01-21 |
| JP2023110030A (ja) | 2023-08-08 |
| TW202320747A (zh) | 2023-06-01 |
| TWI788484B (zh) | 2023-01-01 |
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