ES2877186T3 - Comprimido orodispersable que contiene estetrol - Google Patents

Comprimido orodispersable que contiene estetrol Download PDF

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Publication number
ES2877186T3
ES2877186T3 ES16729601T ES16729601T ES2877186T3 ES 2877186 T3 ES2877186 T3 ES 2877186T3 ES 16729601 T ES16729601 T ES 16729601T ES 16729601 T ES16729601 T ES 16729601T ES 2877186 T3 ES2877186 T3 ES 2877186T3
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ES
Spain
Prior art keywords
weight
dosage unit
estetrol
particles
combinations
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Active
Application number
ES16729601T
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English (en)
Spanish (es)
Inventor
Séverine Francine Isabelle Jaspart
Johannes Jan Platteeuw
Den Heuvel Denny Johan Marijn Van
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Estetra SRL
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Estetra SRL
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Publication of ES2877186T3 publication Critical patent/ES2877186T3/es
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES16729601T 2015-06-18 2016-06-17 Comprimido orodispersable que contiene estetrol Active ES2877186T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15172751 2015-06-18
PCT/EP2016/064071 WO2016203009A1 (en) 2015-06-18 2016-06-17 Orodispersible tablet containing estetrol

Publications (1)

Publication Number Publication Date
ES2877186T3 true ES2877186T3 (es) 2021-11-16

Family

ID=53476700

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16729601T Active ES2877186T3 (es) 2015-06-18 2016-06-17 Comprimido orodispersable que contiene estetrol

Country Status (19)

Country Link
US (1) US10894014B2 (enExample)
EP (1) EP3310345B1 (enExample)
JP (1) JP6866561B2 (enExample)
CN (1) CN107810001A (enExample)
CA (1) CA2988485A1 (enExample)
CY (1) CY1124104T1 (enExample)
DK (1) DK3310345T3 (enExample)
ES (1) ES2877186T3 (enExample)
HR (1) HRP20210668T1 (enExample)
HU (1) HUE054589T2 (enExample)
LT (1) LT3310345T (enExample)
MA (1) MA44205B1 (enExample)
MD (1) MD3310345T2 (enExample)
PL (1) PL3310345T3 (enExample)
PT (1) PT3310345T (enExample)
RS (1) RS61812B1 (enExample)
SI (1) SI3310345T1 (enExample)
SM (1) SMT202100370T1 (enExample)
WO (1) WO2016203009A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
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SG195118A1 (en) 2011-06-01 2013-12-30 Estetra S A Process for the production of estetrol intermediates
PT2714712T (pt) 2011-06-01 2016-11-08 Estetra Sprl Processo para a produção de intermediários de estetrol
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
LT3310346T (lt) 2015-06-18 2021-06-10 Estetra Sprl Burnoje disperguojama tabletė, turinti estetrolio
LT3310345T (lt) 2015-06-18 2021-06-25 Estetra Sprl Burnoje disperguojama tabletė, turinti estetrolio
DK3701944T3 (da) * 2015-06-18 2022-03-14 Estetra Srl Oro-dispergerbar doseringsenhed indeholdende en estetrolkomponent
CR20180042A (es) 2015-06-18 2018-05-03 Mithra Pharmaceuticals S A Unidad de dosificación orodispersable que contiene un componente estetrol.
KR102712911B1 (ko) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
CN111989105B (zh) 2018-04-19 2024-07-19 埃斯特拉私人有限责任公司 化合物以及它们在缓解绝经相关症状中的用途
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
CN112770779B (zh) * 2019-11-07 2022-07-22 旭化成株式会社 纤维素组合物、片剂及口腔崩解片
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
US20230346695A1 (en) 2020-09-29 2023-11-02 Millicent Pharma Limited Orodispersible formulations

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SMT202100370T1 (it) 2021-07-12
MD3310345T2 (ro) 2021-07-31
PL3310345T3 (pl) 2021-10-18
RS61812B1 (sr) 2021-06-30
MA44205A (fr) 2018-04-25
EP3310345B1 (en) 2021-03-31
EP3310345A1 (en) 2018-04-25
WO2016203009A1 (en) 2016-12-22
CA2988485A1 (en) 2016-12-22
CY1124104T1 (el) 2022-05-27
JP6866561B2 (ja) 2021-04-28
SI3310345T1 (sl) 2021-05-31
JP2018517718A (ja) 2018-07-05
CN107810001A (zh) 2018-03-16
LT3310345T (lt) 2021-06-25
HRP20210668T1 (hr) 2021-05-28
DK3310345T3 (da) 2021-05-25
US20180185271A1 (en) 2018-07-05
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HUE054589T2 (hu) 2021-09-28
MA44205B1 (fr) 2021-04-30

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