ES2873204T3 - Diagnóstico y tratamiento de enfermedades autoinmunes - Google Patents

Diagnóstico y tratamiento de enfermedades autoinmunes Download PDF

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Publication number
ES2873204T3
ES2873204T3 ES14855002T ES14855002T ES2873204T3 ES 2873204 T3 ES2873204 T3 ES 2873204T3 ES 14855002 T ES14855002 T ES 14855002T ES 14855002 T ES14855002 T ES 14855002T ES 2873204 T3 ES2873204 T3 ES 2873204T3
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Spain
Prior art keywords
hmwk
cleaved
protein
autoimmune disease
human
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ES14855002T
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English (en)
Spanish (es)
Inventor
Daniel Sexton
Burt Adelman
Andrew Nixon
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81Protease inhibitors
    • G01N2333/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Rehabilitation Therapy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES14855002T 2013-10-21 2014-10-17 Diagnóstico y tratamiento de enfermedades autoinmunes Active ES2873204T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361893542P 2013-10-21 2013-10-21
PCT/US2014/061242 WO2015061182A1 (en) 2013-10-21 2014-10-17 Diagnosis and treatment of autoimmune diseases

Publications (1)

Publication Number Publication Date
ES2873204T3 true ES2873204T3 (es) 2021-11-03

Family

ID=52993412

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14855002T Active ES2873204T3 (es) 2013-10-21 2014-10-17 Diagnóstico y tratamiento de enfermedades autoinmunes

Country Status (14)

Country Link
US (3) US10101344B2 (enExample)
EP (2) EP3913364A1 (enExample)
JP (3) JP6657098B2 (enExample)
KR (3) KR102295623B1 (enExample)
CN (2) CN110658337B (enExample)
AU (4) AU2014340449B2 (enExample)
BR (1) BR112016008975B1 (enExample)
CA (1) CA2927695C (enExample)
DK (1) DK3060908T3 (enExample)
ES (1) ES2873204T3 (enExample)
IL (4) IL284969B (enExample)
PL (1) PL3060908T3 (enExample)
PT (1) PT3060908T (enExample)
WO (1) WO2015061182A1 (enExample)

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CA3037154A1 (en) * 2016-09-16 2018-03-22 Dyax Corp. Protein biomarkers for diseases associated with the contact activation system
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EP4548103A2 (en) * 2022-06-30 2025-05-07 Takeda Pharmaceutical Company Limited Protein biomarkers for lanadelumab treatment

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BR112016008975B1 (pt) 2023-02-28
AU2014340449B2 (en) 2019-10-31
AU2020200423B2 (en) 2022-03-31
BR112016008975A2 (pt) 2017-09-19
AU2020200423A1 (en) 2020-02-13
EP3060908A4 (en) 2017-03-22
JP2020091296A (ja) 2020-06-11
US20190120862A1 (en) 2019-04-25
US20200371120A1 (en) 2020-11-26
EP3060908A1 (en) 2016-08-31
JP2022191343A (ja) 2022-12-27
KR20160089368A (ko) 2016-07-27
PT3060908T (pt) 2021-05-27
US10101344B2 (en) 2018-10-16
AU2022204649A1 (en) 2022-07-21
CN105874332B (zh) 2019-11-12
IL245206B (en) 2020-06-30
PL3060908T3 (pl) 2021-10-25
JP6657098B2 (ja) 2020-03-04
JP2017500584A (ja) 2017-01-05
AU2022204649B2 (en) 2024-08-22
JP7157089B2 (ja) 2022-10-19
IL284969A (en) 2021-08-31
EP3060908B1 (en) 2021-02-24
IL293948A (en) 2022-08-01
WO2015061182A1 (en) 2015-04-30
CA2927695A1 (en) 2015-04-30
IL275368B (en) 2021-08-31
IL284969B (en) 2022-07-01
DK3060908T3 (da) 2021-05-25
US10648990B2 (en) 2020-05-12
KR102485948B1 (ko) 2023-01-06
KR102295623B1 (ko) 2021-08-31
IL275368A (en) 2020-07-30
US12061206B2 (en) 2024-08-13
KR20210107182A (ko) 2021-08-31
AU2024266697A1 (en) 2024-12-12
KR102665705B1 (ko) 2024-05-14
CN105874332A (zh) 2016-08-17
KR20230010003A (ko) 2023-01-17
EP3913364A1 (en) 2021-11-24
IL245206A0 (en) 2016-06-30
CN110658337A (zh) 2020-01-07
AU2014340449A1 (en) 2016-06-02
CA2927695C (en) 2022-03-01
US20160252533A1 (en) 2016-09-01
JP7541560B2 (ja) 2024-08-28
CN110658337B (zh) 2023-06-16

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