JP6657098B2 - 自己免疫疾患の診断と治療 - Google Patents

自己免疫疾患の診断と治療 Download PDF

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JP6657098B2
JP6657098B2 JP2016549205A JP2016549205A JP6657098B2 JP 6657098 B2 JP6657098 B2 JP 6657098B2 JP 2016549205 A JP2016549205 A JP 2016549205A JP 2016549205 A JP2016549205 A JP 2016549205A JP 6657098 B2 JP6657098 B2 JP 6657098B2
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hmwk
truncated
protein
percentage
assay
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JP2017500584A (ja
JP2017500584A5 (enExample
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セックストン，ダニエル，ジェー．
エーデルマン，バート
ニクソン，アンドリュー
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ダイアックス コーポレーション
ダイアックス コーポレーション
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Rehabilitation Therapy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016549205A 2013-10-21 2014-10-17 自己免疫疾患の診断と治療 Active JP6657098B2 (ja)

Applications Claiming Priority (3)

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US201361893542P 2013-10-21 2013-10-21
US61/893,542 2013-10-21
PCT/US2014/061242 WO2015061182A1 (en) 2013-10-21 2014-10-17 Diagnosis and treatment of autoimmune diseases

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JP2017500584A JP2017500584A (ja) 2017-01-05
JP2017500584A5 JP2017500584A5 (enExample) 2017-11-30
JP6657098B2 true JP6657098B2 (ja) 2020-03-04

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JP2016549205A Active JP6657098B2 (ja) 2013-10-21 2014-10-17 自己免疫疾患の診断と治療
JP2020018129A Active JP7157089B2 (ja) 2013-10-21 2020-02-05 自己免疫疾患の診断と治療
JP2022161469A Active JP7541560B2 (ja) 2013-10-21 2022-10-06 自己免疫疾患の診断と治療

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JP2022161469A Active JP7541560B2 (ja) 2013-10-21 2022-10-06 自己免疫疾患の診断と治療

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US (3) US10101344B2 (enExample)
EP (2) EP3913364A1 (enExample)
JP (3) JP6657098B2 (enExample)
KR (3) KR102295623B1 (enExample)
CN (2) CN110658337B (enExample)
AU (4) AU2014340449B2 (enExample)
BR (1) BR112016008975B1 (enExample)
CA (1) CA2927695C (enExample)
DK (1) DK3060908T3 (enExample)
ES (1) ES2873204T3 (enExample)
IL (4) IL284969B (enExample)
PL (1) PL3060908T3 (enExample)
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BR112016008975B1 (pt) 2023-02-28
AU2014340449B2 (en) 2019-10-31
AU2020200423B2 (en) 2022-03-31
BR112016008975A2 (pt) 2017-09-19
AU2020200423A1 (en) 2020-02-13
EP3060908A4 (en) 2017-03-22
JP2020091296A (ja) 2020-06-11
US20190120862A1 (en) 2019-04-25
US20200371120A1 (en) 2020-11-26
EP3060908A1 (en) 2016-08-31
JP2022191343A (ja) 2022-12-27
KR20160089368A (ko) 2016-07-27
PT3060908T (pt) 2021-05-27
US10101344B2 (en) 2018-10-16
AU2022204649A1 (en) 2022-07-21
CN105874332B (zh) 2019-11-12
IL245206B (en) 2020-06-30
PL3060908T3 (pl) 2021-10-25
JP2017500584A (ja) 2017-01-05
AU2022204649B2 (en) 2024-08-22
JP7157089B2 (ja) 2022-10-19
IL284969A (en) 2021-08-31
EP3060908B1 (en) 2021-02-24
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WO2015061182A1 (en) 2015-04-30
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IL275368B (en) 2021-08-31
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DK3060908T3 (da) 2021-05-25
US10648990B2 (en) 2020-05-12
KR102485948B1 (ko) 2023-01-06
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IL275368A (en) 2020-07-30
ES2873204T3 (es) 2021-11-03
US12061206B2 (en) 2024-08-13
KR20210107182A (ko) 2021-08-31
AU2024266697A1 (en) 2024-12-12
KR102665705B1 (ko) 2024-05-14
CN105874332A (zh) 2016-08-17
KR20230010003A (ko) 2023-01-17
EP3913364A1 (en) 2021-11-24
IL245206A0 (en) 2016-06-30
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AU2014340449A1 (en) 2016-06-02
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